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Prevention and earl...
Prevention and early detection of prostate cancer.
- Article/chapterEnglish2014
Publisher, publication year, extent ...
Numbers
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LIBRIS-ID:oai:DiVA.org:uu-238801
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-238801URI
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https://doi.org/10.1016/S1470-2045(14)70211-6DOI
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https://lup.lub.lu.se/record/4738199URI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:129930456URI
Supplementary language notes
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Language:English
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Summary in:English
Part of subdatabase
Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Prostate cancer is a common malignancy in men and the worldwide burden of this disease is rising. Lifestyle modifications such as smoking cessation, exercise, and weight control offer opportunities to reduce the risk of developing prostate cancer. Early detection of prostate cancer by prostate-specific antigen (PSA) screening is controversial, but changes in the PSA threshold, frequency of screening, and the use of other biomarkers have the potential to minimise the overdiagnosis associated with PSA screening. Several new biomarkers for individuals with raised PSA concentrations or those diagnosed with prostate cancer are likely to identify individuals who can be spared aggressive treatment. Several pharmacological agents such as 5α-reductase inhibitors and aspirin could prevent development of prostate cancer. In this Review, we discuss the present evidence and research questions regarding prevention, early detection of prostate cancer, and management of men either at high risk of prostate cancer or diagnosed with low-grade prostate cancer.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
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Thorat, Mangesh A
(author)
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Andriole, Gerald
(author)
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Brawley, Otis W
(author)
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Brown, Powel H
(author)
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Culig, Zoran
(author)
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Eeles, Rosalind A
(author)
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Ford, Leslie G
(author)
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Hamdy, Freddie C
(author)
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Holmberg, LarsUppsala universitet,Institutionen för kirurgiska vetenskaper(Swepub:uu)larsholmb
(author)
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Ilic, Dragan
(author)
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Key, Timothy J
(author)
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La Vecchia, Carlo
(author)
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Lilja, HansLund University,Lunds universitet,Klinisk kemi, Malmö,Forskargrupper vid Lunds universitet,Clinical Chemistry, Malmö,Lund University Research Groups(Swepub:lu)klke-hli
(author)
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Marberger, Michael
(author)
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Meyskens, Frank L
(author)
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Minasian, Lori M
(author)
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Parker, Chris
(author)
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Parnes, Howard L
(author)
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Perner, Sven
(author)
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Rittenhouse, Harry
(author)
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Schalken, Jack
(author)
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Schmid, Hans-Peter
(author)
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Schmitz-Dräger, Bernd J
(author)
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Schröder, Fritz H
(author)
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Stenzl, Arnulf
(author)
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Tombal, Bertrand
(author)
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Wilt, Timothy J
(author)
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Wolk, AlicjaKarolinska Institutet
(author)
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Uppsala universitetInstitutionen för kirurgiska vetenskaper
(creator_code:org_t)
Related titles
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In:The Lancet Oncology15:11, s. e484-921470-20451474-5488
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Cuzick, Jack
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Thorat, Mangesh ...
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Andriole, Gerald
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Brawley, Otis W
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Brown, Powel H
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Culig, Zoran
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Eeles, Rosalind ...
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Ford, Leslie G
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Hamdy, Freddie C
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Holmberg, Lars
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Ilic, Dragan
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Key, Timothy J
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La Vecchia, Carl ...
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Lilja, Hans
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Marberger, Micha ...
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Meyskens, Frank ...
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Minasian, Lori M
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Parker, Chris
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Parnes, Howard L
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Perner, Sven
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Rittenhouse, Har ...
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Schalken, Jack
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Schmid, Hans-Pet ...
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Schmitz-Dräger, ...
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Schröder, Fritz ...
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Stenzl, Arnulf
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Tombal, Bertrand
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Wilt, Timothy J
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Wolk, Alicja
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The Lancet Oncol ...
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Uppsala University
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Karolinska Institutet