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Critical age window...
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Erbas, BircanLa Trobe Univ, Dept Publ Hlth, Melbourne, Vic, Australia
(författare)
Critical age windows in the impact of lifetime smoking exposure on respiratory symptoms and disease among ever smokers
- Artikel/kapitelEngelska2018
Förlag, utgivningsår, omfång ...
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ACADEMIC PRESS INC ELSEVIER SCIENCE,2018
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printrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:uu-356376
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-356376URI
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https://doi.org/10.1016/j.envres.2018.02.028DOI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
Anmärkningar
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Background: Despite extensive knowledge of smoking effects on respiratory disease, there is no study including all age windows of exposure among ever smokers. The objective of this study was to assess the effects from smoking exposure in utero, early childhood, adolescence and adulthood on respiratory health outcomes in adult male and female ever smokers. Methods: Respiratory health outcomes were assessed in 10,610 participants of the European Community Respiratory Health Survey (ECRHS) I who reported a history of ever smoking by questionnaire. The associations of maternal smoking in utero, maternal smoking during childhood, age of smoking debut and pack-years of smoking with respiratory symptoms, obstructive diseases and bronchial hyperreactivity were analysed using generalized linear regression, non-linearity between age of smoking debut and outcomes were assessed by Generalized additive mixed models. Results: Respiratory symptoms and asthma were more frequent in adults if their mother smoked during pregnancy, and, in men, also if mother smoked in childhood. Wheeze and >= 3 respiratory symptoms declined with later smoking debut among women [<= 10 years: OR = 3.51, 95% CI 1.26, 9.73; 11-12 years: 1.57[1.01-2.44]; 13-15 years: 1.11[0.94-1.32] and <= 10 years: 3.74[1.56-8.83]; 11-12 years: 1.76[1.19-2.56]; 13-15 years: 1.12[0.94-1.35], respectively]. Effects of increasing number of packyears were pronounced in women (Chronic Obstructive Pulmonary Disease (COPD): OR/10 packyears women: 1.33 [1.18, 1.50], men: 1.14 [1.04, 1.26] P-interaction = 0.01). Conclusions: Among ever smokers, smoking exposure in each stage of the lifespan show persistent harmful effects for adult respiratory health, while women appeared to be more vulnerable to an early age of smoking debut and amount of smoking in adulthood.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Knudsen, Toril MorkveUniv Bergen, Dept Clin Sci, Bergen, Norway
(författare)
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Janson, ChristerUppsala universitet,Lung- allergi- och sömnforskning(Swepub:uu)chrisjn
(författare)
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Nilsen, Roy M.Haukeland Hosp, Ctr Clin Res, Bergen, Norway
(författare)
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Accordini, SimoneUniv Verona, Dept Publ Hlth & Community Med, Unit Epidemiol & Med Stat, Verona, Italy
(författare)
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Benediktdottir, BryndisUniv Iceland, Landspitali Univ Hosp, Fac Med, Dept Resp Med & Sleep, Reykjavik, Iceland
(författare)
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Dratva, JuliaSwiss Trop & Publ Hlth Inst, Dept Publ Hlth & Epidemiol, Basel, Switzerland;Univ Basel, Basel, Switzerland
(författare)
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Heinrich, JoachimHelmholtz Zentrum, Inst Epidemiol 1, Munich, Germany;Ludwig Maximilian Univ Munich, Univ Hosp Munich, Inst & Outpatient Clin Occupat Social & Environm, Inner City Clin, Munich, Germany
(författare)
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Jarvis, DebbieImperial Coll, Natl Heart & Lung Inst, Dept Resp Epidemiol Occupat Med & Publ Hlth, London, England
(författare)
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Leynaert, BenedciteINSERM, UMR1152, Team Epidemiol, Paris, France
(författare)
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Matheson, Melanie C.Univ Melbourne, Allergy & Lung Hlth Unit, Sch Populat & Global Hlth, Ctr Epidemiol & Biostat, Melbourne, Vic, Australia
(författare)
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Norbäck, DanUppsala universitet,Arbets- och miljömedicin(Swepub:uu)dagnorba
(författare)
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Real, Francisco G.Univ Bergen, Dept Clin Sci, Bergen, Norway;Haukeland Hosp, Dept Gynecol & Obstet, Bergen, Norway
(författare)
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Raherison-Semjen, ChantalBordeaux Univ, Inst Publ Hlth & Epidemiol, INSERM, U897, Bordeaux, France
(författare)
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Villani, SimonaUniv Pavia, Dept Publ Hlth Expt & Forens Med, Unit Biostat & Clin Epidemiol, Pavia, Italy
(författare)
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Dharmage, S. C.Univ Melbourne, Allergy & Lung Hlth Unit, Sch Populat & Global Hlth, Ctr Epidemiol & Biostat, Melbourne, Vic, Australia
(författare)
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Svanes, C.Univ Bergen, Ctr Int Hlth, Bergen, Norway;Haukeland Hosp, Dept Occupat Med, Bergen, Norway
(författare)
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La Trobe Univ, Dept Publ Hlth, Melbourne, Vic, AustraliaUniv Bergen, Dept Clin Sci, Bergen, Norway
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Environmental Research: ACADEMIC PRESS INC ELSEVIER SCIENCE164, s. 241-2470013-93511096-0953
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Erbas, Bircan
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Knudsen, Toril M ...
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Janson, Christer
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Nilsen, Roy M.
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Accordini, Simon ...
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Benediktdottir, ...
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visa fler...
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Dratva, Julia
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Heinrich, Joachi ...
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Jarvis, Debbie
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Leynaert, Benedc ...
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Matheson, Melani ...
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Norbäck, Dan
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Real, Francisco ...
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Raherison-Semjen ...
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Villani, Simona
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Dharmage, S. C.
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Svanes, C.
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