Sökning: onr:"swepub:oai:DiVA.org:uu-394056" > Rationale and Study...
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000 | 14055naa a2202749 4500 | |
001 | oai:DiVA.org:uu-394056 | |
003 | SwePub | |
008 | 191003s2019 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3940562 URI |
024 | 7 | a https://doi.org/10.1053/j.jvca.2019.01.0562 DOI |
040 | a (SwePub)uu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Carraminana, Albertu Hosp Clin Barcelona, Dept Anesthesia & Crit Care, Villarroel 170, Barcelona 08036, Spain4 aut |
245 | 1 0 | a Rationale and Study Design for an Individualized Perioperative Open Lung Ventilatory Strategy in Patients on One-Lung Ventilation (iPROVE-OLV) |
264 | 1 | b W B SAUNDERS CO-ELSEVIER INC,c 2019 |
338 | a print2 rdacarrier | |
520 | a Objective: The aim of this clinical trial is to examine whether it is possible to reduce postoperative complications using an individualized perioperative ventilatory strategy versus using a standard lung-protective ventilation strategy in patients scheduled for thoracic surgery requiring one-lung ventilation. Design: International, multicenter, prospective, randomized controlled clinical trial. Setting: A network of university hospitals. Participants: The study comprises 1,380 patients scheduled for thoracic surgery. Interventions: The individualized group will receive intraoperative recruitment maneuvers followed by individualized positive end-expiratory pressure (open lung approach) during the intraoperative period plus postoperative ventilatory support with high-flow nasal cannula, whereas the control group will be managed with conventional lung-protective ventilation. Measurements and Main Results: Individual and total number of postoperative complications, including atelectasis, pneumothorax, pleural effusion, pneumonia, acute lung injury; unplanned readmission and reintubation; length of stay and death in the critical care unit and in the hospital will be analyzed for both groups. The authors hypothesize that the intraoperative application of an open lung approach followed by an individual indication of high-flow nasal cannula in the postoperative period will reduce pulmonary complications and length of hospital stay in high-risk surgical patients. (C) 2019 Published by Elsevier Inc. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Anestesi och intensivvård0 (SwePub)302012 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Anesthesiology and Intensive Care0 (SwePub)302012 hsv//eng |
653 | a mechanical ventilation | |
653 | a postoperative pulmonary complications | |
653 | a one-lung ventilation | |
653 | a positive end-expiratory pressure | |
653 | a recruitment maneuvers | |
700 | 1 | a Ferrando, Carlosu Hosp Clin Barcelona, Dept Anesthesia & Crit Care, Villarroel 170, Barcelona 08036, Spain;Inst Salud Carlos III, CIBER Enfermedades Resp, Madrid, Spain4 aut |
700 | 1 | a Unzueta, M. Carmenu Hosp Santa Creu & Sant Pau, Dept Anesthesia & Crit Care, Barcelona, Spain4 aut |
700 | 1 | a Navarro, Ricardu Hosp Clin Barcelona, Dept Anesthesia & Crit Care, Villarroel 170, Barcelona 08036, Spain4 aut |
700 | 1 | a Suarez-Sipmann, Fernandou Uppsala universitet,Hedenstiernalaboratoriet,Inst Salud Carlos III, CIBER Enfermedades Resp, Madrid, Spain;Hosp La Princesa, Intens Care Unit, Madrid, Spain;4 aut0 (Swepub:uu)fersi946 |
700 | 1 | a Tusman, Gerardou Hosp Privado Mar De Plata, Dept Anesthesia, Mar De Plata, Argentina4 aut |
700 | 1 | a Garutti, Ignaciou Hosp Univ Gregorio Maranon, Dept Anesthesia & Crit Care, Madrid, Spain4 aut |
700 | 1 | a Soro, Marinau Hosp Clin Valencia, Dept Anesthesia & Crit Care, Valencia, Spain4 aut |
700 | 1 | a Pozo, Natividadu Hosp Clin Univ Valencia, Inst INCLIVA, Valencia, Spain4 aut |
700 | 1 | a Librero, Julianu Red Invest Serv Salud Enfermedades Cron REDISSEC, Navarrabiomed Fdn Miguel Servet, Pamplona, Spain4 aut |
700 | 1 | a Gallego, Luciau Hosp Miguel Servet, Dept Anesthesia & Crit Care, Zaragoza, Spain4 aut |
700 | 1 | a Ramasco, Fernandou Hosp La Princesa, Dept Anesthesia & Crit Care, Madrid, Spain4 aut |
700 | 1 | a Rabanal, Jose M.u Hosp Marques Valdecilla, Dept Anesthesia & Crit Care, Santander, Spain4 aut |
700 | 1 | a Rodriguez, Aureliou Hosp Univ Dr Negrin, Dept Anesthesia, Las Palmas Gran Canaria, Spain4 aut |
700 | 1 | a Sastre, Joseu Hosp Salamanca, Dept Anesthesia & Crit Care T, Salamanca, Spain4 aut |
700 | 1 | a Martinez, Jesusu Hosp Univ Mutua Terrassa, Dept Anesthesia & Crit Care, Terrassa, Spain4 aut |
700 | 1 | a Coves, Silviau Hosp Univ Vinalopo, Dept Anesthesia & Crit Care, Elche, Spain4 aut |
700 | 1 | a Garcia, Pablou Hosp 12 Octubre, Dept Anesthesia & Crit Care, Madrid, Spain4 aut |
700 | 1 | a Aguirre-Puig, Pilaru Hosp Alvaro Cunqueiro, Dept Anesthesia & Crit Care, Vigo, Spain4 aut |
700 | 1 | a Yepes, Joseu Clin Univ Pamplona, Dept Anesthesia & Crit Care, Pamplona, Spain4 aut |
700 | 1 | a Lluch, Aitanau Hosp Univ La Fe, Dept Anesthesia & Crit Care, Valencia, Spain4 aut |
700 | 1 | a Lopez-Herrera, Danielu Hosp Viigen Rocio, Dept Anesthesia & Crit Care, Seville, Spain4 aut |
700 | 1 | a Leal, Sonsolesu Hosp Povisa, Dept Anesthesia & Crit Care, Vigo, Spain4 aut |
700 | 1 | a Vives, Marcu Hosp Dr Josep Trueta, Dept Anesthesia & Crit Care, Girona, Spain4 aut |
700 | 1 | a Bellas, Soledadu Fdn Jimenez Diaz, Dept Anesthesia & Crit Care, Madrid, Spain4 aut |
700 | 1 | a Socorro, Taniau Complejo Univ MaternoInsular, Dept Anesthesia, Las Palmas Gran Canaria, Spain4 aut |
700 | 1 | a Trespalacios, Ramonu Hosp Univ Cent Asturias, Dept Anesthesia & Crit Care, Oviedo, Spain4 aut |
700 | 1 | a Salazar, Claudia J.u Hosp Univ Canarias, Dept Anesthesia & Crit Care, Tenerife, Spain4 aut |
700 | 1 | a Mugarra, Anau Hosp Clin Valencia, Dept Anesthesia & Crit Care, Valencia, Spain4 aut |
700 | 1 | a Cinnella, Gildau Univ Foggia, Dept Anesthesia & Crit Care, Foggia, Italy4 aut |
700 | 1 | a Spadaro, Savinou Univ Ferrara, Dept Anesthesia & Crit Care, Ferrara, Italy4 aut |
700 | 1 | a Futier, Emmanuelu CHU Clermont Ferrand, Anesthesia & Crit Care, Clermont Ferrand, France4 aut |
700 | 1 | a Ferrer, Leopoldou Univ El Basque, Dept Anesthesia, Bogota, Colombia4 aut |
700 | 1 | a Cabrera, Mariau Hosp Clin Fuerza Aerea Chile, Dept Anesthesia, Los Condes, Chile4 aut |
700 | 1 | a Ribeiro, Helderu Ctr Hosp Sao Joao, Dept Anesthesia & Crit Care, Porto, Portugal4 aut |
700 | 1 | a Celestino, Catarinau Ctr Hosp Vila Nova Gaia Espinho, Dept Anesthesia & Crit Care, Vila Nova De Gaia, Portugal4 aut |
700 | 1 | a Kucur, Evrimu Med Pk Bahcelievler Hosp, Anesthesia & Crit Care, Istanbul, Turkey4 aut |
700 | 1 | a Cervantes, Oriolu Hosp Badalona Germans Trias & Pujol, Dept Anesthesia & Crit Care, Badalona, Spain4 aut |
700 | 1 | a Morocho, Diegou Hosp Especialidades Eugenio Espejo, Crit Care Dept, Quito, Ecuador4 aut |
700 | 1 | a Delphy, Daliau Alexandria Univ Hosp, Dept Anesthesia, Alexandria, Egypt;Kafrelsheikh Univ Hosp, Alexandria, Egypt4 aut |
700 | 1 | a Ramos, Carolinau Hosp Univ Ntra Sra Candelaria, Dept Anesthesia & Crit Care, Santa Cruz De Tenerife, Spain4 aut |
700 | 1 | a Villar, Jesusu Inst Salud Carlos III, CIBER Enfermedades Resp, Madrid, Spain;Hosp Univ Dr Negrin, Res Unit, Las Palmas Gran Canaria, Spain4 aut |
700 | 1 | a Belda, Javieru Hosp Clin Valencia, Dept Anesthesia & Crit Care, Valencia, Spain4 aut |
700 | 1 | a Monedero, Pablo4 aut |
700 | 1 | a Martinez, Samira4 aut |
700 | 1 | a Comino, Oscar4 aut |
700 | 1 | a Coy, Alberto4 aut |
700 | 1 | a Armengol, Laura4 aut |
700 | 1 | a Pineiro, Patricia4 aut |
700 | 1 | a Cruz, Patricia4 aut |
700 | 1 | a Duque, Patricia4 aut |
700 | 1 | a Andres de la Gala, Francisco4 aut |
700 | 1 | a Sanchez, Guillermo4 aut |
700 | 1 | a Olmedilla, Luis4 aut |
700 | 1 | a de la Fuente, Elena4 aut |
700 | 1 | a Erquicia, Inaqui4 aut |
700 | 1 | a Reyes, Almudena4 aut |
700 | 1 | a Lopez, Elena4 aut |
700 | 1 | a Palencia, Maria4 aut |
700 | 1 | a Bunger, Beatriz4 aut |
700 | 1 | a Ramos, Rafael4 aut |
700 | 1 | a Terradillos, Estrella4 aut |
700 | 1 | a Almaraz, Carolina4 aut |
700 | 1 | a Minguez Lujan, Laura4 aut |
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700 | 1 | a Femenia, Francisco4 aut |
700 | 1 | a Botella, Santiago4 aut |
700 | 1 | a Cimadevilla, Bonifacio4 aut |
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700 | 1 | a Lopez, Carlos4 aut |
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700 | 1 | a Hernandez, Jessica4 aut |
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700 | 1 | a Solera, Jorge4 aut |
700 | 1 | a Guerra, Elisabet4 aut |
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700 | 1 | a Pilar Arribas, Maria4 aut |
700 | 1 | a Alfonso Sastre, Jose4 aut |
700 | 1 | a de Celis, Isabel4 aut |
700 | 1 | a Jesus Pascual, Maria4 aut |
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700 | 1 | a Arango, Enrique4 aut |
700 | 1 | a Amaya, Oswaldo4 aut |
700 | 1 | a Madrid, Guillermo4 aut |
700 | 1 | a Triana, Carlos4 aut |
700 | 1 | a Pabon, Stefanie4 aut |
700 | 1 | a Paola Diaz, Diana4 aut |
700 | 1 | a Ortells, Fernando4 aut |
700 | 1 | a Perez, Bernardino4 aut |
700 | 1 | a Aracil, Ruth4 aut |
700 | 1 | a Sanchez, Raquel4 aut |
700 | 1 | a Acosta, Jesus4 aut |
700 | 1 | a de la Matta, Manuel4 aut |
700 | 1 | a Gonzalez, Domingo4 aut |
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700 | 1 | a Rauseo, Michela4 aut |
700 | 1 | a Lamanna, Angela4 aut |
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700 | 1 | a Ragazzi, Riccardo4 aut |
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700 | 1 | a Azparren, Gonzalo4 aut |
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700 | 1 | a Visiedo, Sara4 aut |
700 | 1 | a Cordoba, Jose4 aut |
700 | 1 | a Pintor, Jestis4 aut |
700 | 1 | a Planas, Antonio4 aut |
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700 | 1 | a Jose Parra, Maria4 aut |
700 | 1 | a Antonio Carbonell, Jose4 aut |
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700 | 1 | a Cuervo, Javier4 aut |
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700 | 1 | a Martinez, Sara4 aut |
700 | 1 | a Monleon, Berta4 aut |
700 | 1 | a Garcia, Laura4 aut |
700 | 1 | a Hurtado, Luis4 aut |
700 | 1 | a Pardo, Pablo4 aut |
700 | 1 | a Segura, Nasara4 aut |
700 | 1 | a Utrera, Esther4 aut |
700 | 1 | a Martin, Beatriz4 aut |
700 | 1 | a Mellado, Patricia4 aut |
700 | 1 | a Juan Arcas, Jose4 aut |
700 | 1 | a Martinez, Nuria4 aut |
700 | 1 | a Maric, Marina4 aut |
700 | 1 | a Enrique Munoz, Luis4 aut |
700 | 1 | a Callejas Gonzalez, Raquel4 aut |
700 | 1 | a Busquets, Jordi4 aut |
700 | 1 | a Homs, Marta4 aut |
700 | 1 | a Jimenez, Anabel4 aut |
700 | 1 | a Pintanel, Teresa4 aut |
700 | 1 | a Martinez, Esther4 aut |
700 | 1 | a Moret, Enric4 aut |
700 | 1 | a Sercakacilar, Gokhan4 aut |
700 | 1 | a Diaz, Maria4 aut |
700 | 1 | a Tiago Souteiro, Joao4 aut |
700 | 1 | a Benito, Alba4 aut |
700 | 1 | a Cebrian, Alba4 aut |
700 | 1 | a Mestres, Gerard4 aut |
700 | 1 | a Ibrahim Mohamed, Mohamed4 aut |
700 | 1 | a Ahmed Yousef, Shahira4 aut |
700 | 1 | a Mohamed Osman, Yasser4 aut |
700 | 1 | a Moreno, Andres4 aut |
700 | 1 | a Tutillo, Andres4 aut |
700 | 1 | a Pilco, Henry4 aut |
700 | 1 | a Pena, Andrea4 aut |
700 | 1 | a Llano, Miguel4 aut |
700 | 1 | a Carrillo, Elizabeth4 aut |
700 | 1 | a Salazar, Claudia4 aut |
700 | 1 | a Dominguez, David4 aut |
700 | 1 | a Espinosa, Elena4 aut |
710 | 2 | a Hosp Clin Barcelona, Dept Anesthesia & Crit Care, Villarroel 170, Barcelona 08036, Spainb Hosp Clin Barcelona, Dept Anesthesia & Crit Care, Villarroel 170, Barcelona 08036, Spain;Inst Salud Carlos III, CIBER Enfermedades Resp, Madrid, Spain4 org |
773 | 0 | t Journal of Cardiothoracic and Vascular Anesthesiad : W B SAUNDERS CO-ELSEVIER INCg 33:9, s. 2492-2502q 33:9<2492-2502x 1053-0770x 1532-8422 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-394056 |
856 | 4 8 | u https://doi.org/10.1053/j.jvca.2019.01.056 |
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