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Ancient human genom...
Ancient human genome sequence of an extinct Palaeo-Eskimo
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Rasmussen, Morten (author)
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Li, Yingrui (author)
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Lindgreen, Stinus (author)
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Pedersen, Jakob Skou (author)
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Albrechtsen, Anders (author)
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Moltke, Ida (author)
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Metspalu, Mait (author)
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Metspalu, Ene (author)
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Kivisild, Toomas (author)
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Gupta, Ramneek (author)
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Bertalan, Marcelo (author)
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Nielsen, Kasper (author)
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Gilbert, M. Thomas P. (author)
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Wang, Yong (author)
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Raghavan, Maanasa (author)
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Campos, Paula F. (author)
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Kamp, Hanne Munkholm (author)
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Wilson, Andrew S. (author)
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Gledhill, Andrew (author)
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Tridico, Silvana (author)
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Bunce, Michael (author)
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Lorenzen, Eline D. (author)
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Binladen, Jonas (author)
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Guo, Xiaosen (author)
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Zhao, Jing (author)
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Zhang, Xiuqing (author)
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Zhang, Hao (author)
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Li, Zhuo (author)
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- Villems, Richard (author)
- Uppsala universitet,Kollegiet för avancerade studier (SCAS)
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Chen, Minfeng (author)
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Orlando, Ludovic (author)
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Kristiansen, Karsten (author)
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Bak, Mads (author)
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Tommerup, Niels (author)
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Bendixen, Christian (author)
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Pierre, Tracey L. (author)
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Grønnow, Bjarne (author)
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Meldgaard, Morten (author)
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Andreasen, Claus (author)
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Fedorova, Sardana A. (author)
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Osipova, Ludmila P. (author)
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Higham, Thomas F. G. (author)
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Ramsey, Christopher Bronk (author)
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Hansen, Thomas v. O. (author)
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Nielsen, Finn C. (author)
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Crawford, Michael H. (author)
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Brunak, Søren (author)
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Sicheritz-Pontén, Thomas (author)
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Nielsen, Rasmus (author)
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Krogh, Anders (author)
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Wang, Jun (author)
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Willerslev, Eske (author)
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(creator_code:org_t)
- Springer Science and Business Media LLC, 2010
- 2010
- English.
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In: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 463:7282, s. 757-762
- Related links:
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https://doi.org/10.1...
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https://www.nature.c...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
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- We report here the genome sequence of an ancient human. Obtained from ∼4,000-year-old permafrost-preserved hair, the genome represents a male individual from the first known culture to settle in Greenland. Sequenced to an average depth of 20×, we recover 79% of the diploid genome, an amount close to the practical limit of current sequencing technologies. We identify 353,151 high-confidence single-nucleotide polymorphisms (SNPs), of which 6.8% have not been reported previously. We estimate raw read contamination to be no higher than 0.8%. We use functional SNP assessment to assign possible phenotypic characteristics of the individual that belonged to a culture whose location has yielded only trace human remains. We compare the high-confidence SNPs to those of contemporary populations to find the populations most closely related to the individual. This provides evidence for a migration from Siberia into the New World some 5,500 years ago, independent of that giving rise to the modern Native Americans and Inuit.
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- ref (subject category)
- art (subject category)
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- By the author/editor
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Rasmussen, Morte ...
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Li, Yingrui
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Lindgreen, Stinu ...
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Pedersen, Jakob ...
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Albrechtsen, And ...
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Moltke, Ida
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show more...
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Metspalu, Mait
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Metspalu, Ene
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Kivisild, Toomas
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Gupta, Ramneek
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Bertalan, Marcel ...
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Nielsen, Kasper
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Gilbert, M. Thom ...
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Wang, Yong
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Raghavan, Maanas ...
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Campos, Paula F.
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Kamp, Hanne Munk ...
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Wilson, Andrew S ...
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Gledhill, Andrew
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Tridico, Silvana
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Bunce, Michael
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Lorenzen, Eline ...
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Binladen, Jonas
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Guo, Xiaosen
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Zhao, Jing
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Zhang, Xiuqing
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Zhang, Hao
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Li, Zhuo
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Villems, Richard
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Chen, Minfeng
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Orlando, Ludovic
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Kristiansen, Kar ...
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Bak, Mads
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Tommerup, Niels
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Bendixen, Christ ...
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Pierre, Tracey L ...
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Grønnow, Bjarne
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Meldgaard, Morte ...
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Andreasen, Claus
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Fedorova, Sardan ...
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Osipova, Ludmila ...
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Higham, Thomas F ...
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Ramsey, Christop ...
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Hansen, Thomas v ...
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Nielsen, Finn C.
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Crawford, Michae ...
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Brunak, Søren
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Sicheritz-Pontén ...
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Nielsen, Rasmus
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Krogh, Anders
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Wang, Jun
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Willerslev, Eske
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show less...
- Articles in the publication
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Nature
- By the university
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Uppsala University