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Phadiatop, Phadiato...
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Pierotti, Felipe FariaUniv Fed Sao Paulo, Sao Paulo, SP, Brazil.
(author)
Phadiatop, Phadiatop Infant and total IgE evaluated in allergic Brazilian children and adolescents
- Article/chapterEnglish2020
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ELSEVIER ESPANA SLU,2020
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printrdacarrier
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LIBRIS-ID:oai:DiVA.org:uu-418025
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-418025URI
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https://doi.org/10.1016/j.aller.2019.06.013DOI
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Language:English
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Summary in:English
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
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The clinical history is of importance in the investigation of allergic diseases but does have limitations. Many allergic conditions will be over-diagnosed if anamnesis alone is used for diagnostic criteria. Serum total immunoglobulin E (TIgE) quantification, as well as panels containing allergens prevalent in the studied population, may serve as screening tests and facilitate the diagnosis of allergic disease or its exclusion. We assessed the positivity of two versions of these tests, Phadiatop Europe (R) (PhEU) and Phadiatop Infant (R) (PhInf), as well as total IgE (TigE) values in patients with a medical diagnosis of allergic disease and non-allergic individuals. Methods: A cross-sectional study performed in eleven Brazilian pediatric allergy centers with patients divided into groups according to the primary condition and a group of assessed control subjects. They were submitted to TIgE measurement and screening tests (PhEu and PhInf). Results: TIgE mean serum levels were significantly higher among allergic patients, especially those with asthma/rhinitis or atopic dermatitis. The positivity of the screening tests, considering the total population, was 63.8% for PhEU and 72.6% for PhInf. These increased when we evaluated only the allergic subjects. The concordance index of the two tests was Kappa=0.7 and higher among those of greater age. Conclusions: In the assessed population, there were significantly higher levels among those with positive screening tests and PhInf showed better performance in the identification of sensitized individuals, regardless of age. This is the first study to evaluate Phadiatop and Phadiatop Infant in the same population. (C) 2019 SEICAP. Published by Elsevier Espana, S.L.U. All rights reserved.
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Aranda, Carolina SanchezUniv Fed Sao Paulo, Sao Paulo, SP, Brazil.
(author)
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Cocco, Renata RodriguesUniv Fed Sao Paulo, Sao Paulo, SP, Brazil.
(author)
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Sarinho, EmanuelUniv Fed Pernambuco, Recife, PE, Brazil.
(author)
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Sano, FlavioNipo Brasileiro Hosp, Sao Paulo, SP, Brazil.
(author)
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Porto, ArnaldoUniv Passo Fundo, Passo Fundo, RS, Brazil.
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Rosario, NelsonUniv Fed Parana, Curitiba, Parana, Brazil.
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Chong Neto, Herberto JoseUniv Fed Parana, Curitiba, Parana, Brazil.
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Goudouris, EkateriniUniv Fed Rio de Janeiro, Rio De Janeiro, RJ, Brazil.
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Moraes, Lilian SanchesUniv Fed Mato Grosso, Cuiaba, Mato Grosso, Brazil.
(author)
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Wandalsen, Neusa FalboMed Univ Santo Andre, Sao Paulo, SP, Brazil.
(author)
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Mallozi, Marcia CarvalhoMed Univ Santo Andre, Sao Paulo, SP, Brazil.
(author)
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Pastorino, Antonio CarlosUniv Sao Paulo, Sao Paulo, SP, Brazil.
(author)
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Franco, Jackeline MottaUniv Fed Sergipe, Sao Cristovao, Sergipe, Brazil.
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Chavarria, Maria LeticiaUniv Fed Goias, Goiania, Go, Brazil.
(author)
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Borres, Magnus P,1956-Uppsala universitet,Pediatrisk inflammations- och metabolismforskning samt barnhälsa,Thermo Fisher Sci, Uppsala, Sweden(Swepub:uu)magbo385
(author)
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Sole, DirceuUniv Fed Sao Paulo, Sao Paulo, SP, Brazil.
(author)
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Univ Fed Sao Paulo, Sao Paulo, SP, Brazil.Univ Fed Pernambuco, Recife, PE, Brazil.
(creator_code:org_t)
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In:Allergologia et Immunopathologia: ELSEVIER ESPANA SLU48:3, s. 259-2640301-05461578-1267
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