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Sex differences in ...
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Kimenai, Dorien M.Univ Edinburgh, Usher Inst, Edinburgh EH16 4SA, Midlothian, Scotland.
(författare)
Sex differences in investigations and outcomes among patients with type 2 myocardial infarction
- Artikel/kapitelEngelska2021
Förlag, utgivningsår, omfång ...
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2021-04-20
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BMJ Publishing Group Ltd,2021
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electronicrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:uu-456922
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-456922URI
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https://doi.org/10.1136/heartjnl-2021-319118DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:147690798URI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:art swepub-publicationtype
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Objectives: Type 2 myocardial infarction (MI) is a heterogenous condition and whether there are differences between women and men is unknown. We evaluated sex differences in clinical characteristics, investigations and outcomes in patients with type 2 MI.Methods: In the Swedish Web based system for Enhancement and Development of Evidence based care in Heart disease Evaluated According to Recommended Therapies (SWEDEHEART) registry, we compared patients admitted to coronary care units with a diagnosis of type 1 or type 2 MI. Sex-stratified Cox regression models evaluated the association with all-cause death in men and women separately.Results: We included 57 264 (median age 73 years, 65% men) and 6485 (median age 78 years, 50% men) patients with type 1 and type 2 MI, respectively. No differences were observed in the proportion of men and women with type 2 MI who underwent echocardiography and coronary angiography, but women were less likely than men to have left ventricular (LV) impairment and obstructive coronary artery disease (CAD). Compared with type 1 MI, patients with type 2 MI had higher risk of death regardless of sex (men: adjusted HR 1.55 (95% CI 1.44 to 1.67); women: adjusted HR 1.34 (95% CI 1.24 to 1.45)). In those with type 2 MI, the risk of death was lower for women than men (adjusted HR 0.85 (95% CI 0.76 to 0.92) (men, reference)).Conclusions: Type 2 MI occurred in men and women equally and we found no evidence of sex bias in the selection of patients for cardiac investigations. Patients with type 2 MI had worse outcomes, but women were less likely to have obstructive CAD or severe LV impairment and were more likely to survive than men.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Lindahl, Bertil,1957-Uppsala universitet,Kardiologi,Uppsala kliniska forskningscentrum (UCR)(Swepub:uu)belin227
(författare)
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Chapman, Andrew R.Univ Edinburgh, BHF, Ctr Cardiovasc Sci, Edinburgh, Midlothian, Scotland.
(författare)
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Baron, TomaszUppsala universitet,Kardiologi(Swepub:uu)tomba515
(författare)
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Gard, AntonUppsala universitet,Kardiologi(Swepub:uu)antga822
(författare)
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Wereski, RyanUniv Edinburgh, BHF, Ctr Cardiovasc Sci, Edinburgh, Midlothian, Scotland.
(författare)
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Meex, Steven J. R.Maastricht Univ, Med Ctr, Cent Diagnost Lab, Maastricht, Netherlands.;Maastricht Univ, CARIM, Sch Cardiovasc Dis, Maastricht, Netherlands.
(författare)
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Jernberg, TomasKarolinska Institutet,Danderyd Hosp, Karolinska Inst, Dept Clin Sci, Stockholm, Sweden.
(författare)
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Mills, Nicholas L.Univ Edinburgh, Usher Inst, Edinburgh EH16 4SA, Midlothian, Scotland.;Univ Edinburgh, BHF, Ctr Cardiovasc Sci, Edinburgh, Midlothian, Scotland.
(författare)
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Eggers, Kai M.,1962-Uppsala universitet,Kardiologi(Swepub:uu)kaieg561
(författare)
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Univ Edinburgh, Usher Inst, Edinburgh EH16 4SA, Midlothian, Scotland.Kardiologi
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Heart: BMJ Publishing Group Ltd107:18, s. 1480-14861355-60371468-201X
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Kimenai, Dorien ...
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Lindahl, Bertil, ...
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Chapman, Andrew ...
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Baron, Tomasz
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Gard, Anton
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Wereski, Ryan
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Meex, Steven J. ...
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Jernberg, Tomas
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Mills, Nicholas ...
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Eggers, Kai M., ...
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- MEDICIN OCH HÄLSOVETENSKAP
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och Klinisk medicin
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Heart
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