Sökning: onr:"swepub:oai:DiVA.org:uu-470192" > Decreased renal per...
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000 | 04625naa a2200457 4500 | |
001 | oai:DiVA.org:uu-470192 | |
003 | SwePub | |
008 | 220321s2022 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4701922 URI |
024 | 7 | a https://doi.org/10.1186/s13054-022-04132-82 DOI |
040 | a (SwePub)uu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Luther, Tomasu Uppsala universitet,Anestesiologi och intensivvård4 aut0 (Swepub:uu)tomek221 |
245 | 1 0 | a Decreased renal perfusion during acute kidney injury in critical COVID-19 assessed by magnetic resonance imaging :b a prospective case control study |
264 | c 2022-09-01 | |
264 | 1 | b Springer Nature,c 2022 |
338 | a electronic2 rdacarrier | |
500 | a Title in dissertation list of papers: Decreased perfusion during acute kidney injury in critical COVID-19 assessed by magnetic resonance imaging.De två första författarna delar förstaförfattarskapet.De två sista författarna delar sistaförfattarskapet. | |
520 | a Renal hypoperfusion has been suggested to contribute to the development of acute kidney injury (AKI) in critical COVID-19. However, limited data support this. In this prospective case-control study we aimed to investigate differences in renal perfusion, oxygenation and water diffusion using multiparametric magnetic resonance imaging (mpMRI) in critically ill COVID-19 patients with and without AKI. Nineteen patients without prior kidney disease treated in intensive care for respiratory failure were examined. Ten patients had AKI and nine patients did not have AKI using Kidney Disease: Improving Global Outcomes Creatinine criteria. Age and baseline Plasma-Creatinine were similar in both groups. Total renal blood flow was lower in patients with AKI compared with patients without (median 645 quartile range [423-753] vs. 859 [746-920] ml/min, P = 0.037). Regional perfusion was reduced in both cortex (76 [51-112] vs. 146 [123-169] mL/100g/min, P = 0.015) and medulla (28 [18-47] vs. 47 [38-73] mL/100g/min, P = 0.03). Renal venous saturation was similar in both groups (72% [64-75] vs. 72% [63-84], ns.), as was regional oxygenation (R2*) in cortex (17 [16-19] vs. 17 [16-18] 1/s, ns.) and medulla (29 [24-39] vs. 27 [23-29] 1/s, ns.). We conclude that in critically ill COVID-19 patients with AKI, the total, cortical and medullary renal blood flow are reduced compared with similar patients without AKI, whereas no differences in renal oxygenation were demonstrable in this setting. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Radiologi och bildbehandling0 (SwePub)302082 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Radiology, Nuclear Medicine and Medical Imaging0 (SwePub)302082 hsv//eng |
700 | 1 | a Eckerbom, Per,d 1974-u Uppsala universitet,Radiologi4 aut0 (Swepub:uu)perec430 |
700 | 1 | a Cox, Eleanoru Sir Peter Mansfield Imaging Centre, School of Physics & Astronomy, University of Nottingham, Nottingham, UK4 aut |
700 | 1 | a Lipcsey, Miklósu Uppsala universitet,Hedenstiernalaboratoriet4 aut0 (Swepub:uu)milip123 |
700 | 1 | a Bülow, Sarau Uppsala universitet,Anestesiologi och intensivvård4 aut0 (Swepub:uu)sarbu486 |
700 | 1 | a Hultström, Michael,d 1978-u Uppsala universitet,Institutionen för medicinsk cellbiologi,Anestesiologi och intensivvård4 aut0 (Swepub:uu)mihul498 |
700 | 1 | a Martinez Torrente, Franciscou Uppsala universitet,Anestesiologi och intensivvård4 aut0 (Swepub:uu)frama294 |
700 | 1 | a Weis, Jan,d 1956-u Uppsala universitet,Radiologi4 aut0 (Swepub:uu)janweis |
700 | 1 | a Palm, Fredrik,d 1973-u Uppsala universitet,Institutionen för medicinsk cellbiologi4 aut0 (Swepub:uu)fredpalm |
700 | 1 | a Francis, Susanu Sir Peter Mansfield Imaging Centre, School of Physics & Astronomy, University of Nottingham, Nottingham, UK4 aut |
700 | 1 | a Frithiof, Robertu Uppsala universitet,Anestesiologi och intensivvård4 aut0 (Swepub:uu)robfr118 |
700 | 1 | a Liss, Per,d 1960-u Uppsala universitet,Radiologi4 aut0 (Swepub:uu)perliss |
710 | 2 | a Uppsala universitetb Anestesiologi och intensivvård4 org |
773 | 0 | t Critical Cared : Springer Natureg 26q 26x 1364-8535x 1466-609X |
856 | 4 | u https://doi.org/10.1186/s13054-022-04132-8y Fulltext |
856 | 4 | u https://uu.diva-portal.org/smash/get/diva2:1646280/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-470192 |
856 | 4 8 | u https://doi.org/10.1186/s13054-022-04132-8 |
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