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Sökning: onr:"swepub:oai:DiVA.org:uu-489606" > Identifying a core ...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005234naa a2200769 4500
001oai:DiVA.org:uu-489606
003SwePub
008221201s2023 | |||||||||||000 ||eng|
009oai:prod.swepub.kib.ki.se:150232834
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4896062 URI
0247 a https://doi.org/10.1093/dote/doac0382 DOI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1502328342 URI
040 a (SwePub)uud (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Chidambaram, Swathikan4 aut
2451 0a Identifying a core symptom set triggering radiological and endoscopic investigations for suspected recurrent esophago-gastric cancer :b a modified Delphi consensus process
264 c 2022-07-21
264 1b Oxford University Press,c 2023
338 a electronic2 rdacarrier
520 a BACKGROUND: There is currently a lack of evidence-based guidelines regarding surveillance for recurrence after esophageal and gastric (OG) cancer surgical resection, and which symptoms should prompt endoscopic or radiological investigations for recurrence. The aim of this study was to develop a core symptom set using a modified Delphi consensus process that should guide clinicians to carry out investigations to look for suspected recurrent OG cancer in previously asymptomatic patients.METHODS: A web-based survey of 42 questions was sent to surgeons performing OG cancer resections at high volume centers. The first section evaluated the structure of follow-up and the second, determinants of follow-up. Two rounds of a modified Delphi consensus process and a further consensus workshop were used to determine symptoms warranting further investigations. Symptoms with a 75% consensus agreement as suggestive of recurrent cancer were included in the core symptom set.RESULTS: 27 surgeons completed the questionnaires. A total of 70.3% of centers reported standardized surveillance protocols, whereas 3.7% of surgeons did not undertake any surveillance in asymptomatic patients after OG cancer resection. In asymptomatic patients, 40.1% and 25.9% of centers performed routine imaging and endoscopy, respectively. The core set that reached consensus, consisted of eight symptoms that warranted further investigations included; dysphagia to solid food, dysphagia to liquids, vomiting, abdominal pain, chest pain, regurgitation of foods, unexpected weight loss and progressive hoarseness of voice.CONCLUSION: There is global variation in monitoring patients after OG cancer resection. Eight symptoms were identified by the consensus process as important in prompting radiological or endoscopic investigation for suspected recurrent malignancy. Further randomized controlled trials are necessary to link surveillance strategies to survival outcomes and evaluate prognostic value.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kirurgi0 (SwePub)302122 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Surgery0 (SwePub)302122 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng
653 a endoscopic
653 a esophageal cancer
653 a gastric cancer
653 a surveillance
653 a symptom
7001 a Patel, Nikhil M4 aut
7001 a Sounderajah, Viknesh4 aut
7001 a Alfieri, Rita4 aut
7001 a Bonavina, Luigi4 aut
7001 a Cheong, Edward4 aut
7001 a Cockbain, Andy4 aut
7001 a D'Journo, Xavier Benoit4 aut
7001 a Ferri, Lorenzo4 aut
7001 a Griffiths, Ewen A4 aut
7001 a Grimminger, Peter4 aut
7001 a Gronnier, Caroline4 aut
7001 a Gutschow, Christian4 aut
7001 a Hedberg, Jakob,d 1972-u Karolinska Institutet,Uppsala universitet,Gastrointestinalkirurgi4 aut0 (Swepub:uu)jakhe890
7001 a Kauppila, Joonas H4 aut
7001 a Lagarde, Sjoerd4 aut
7001 a Low, Donald4 aut
7001 a Nafteux, Philippe4 aut
7001 a Nieuwenhuijzen, Grard4 aut
7001 a Nilsson, Magnusu Karolinska Institutet4 aut
7001 a Rosati, Riccardo4 aut
7001 a Schroeder, Wolfgang4 aut
7001 a Smithers, B Mark4 aut
7001 a van Berge Henegouwen, Mark I4 aut
7001 a van Hillegesberg, Richard4 aut
7001 a Watson, David I4 aut
7001 a Vohra, Ravinder4 aut
7001 a Maynard, Nick4 aut
7001 a Markar, Sheraz R4 aut
7102 a Uppsala universitetb Gastrointestinalkirurgi4 org
7730 t Diseases of the esophagusd : Oxford University Pressg 36:1q 36:1x 1120-8694x 1442-2050
8564 u https://doi.org/10.1093/dote/doac038y Fulltext
8564 u https://uu.diva-portal.org/smash/get/diva2:1715274/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-489606
8564 8u https://doi.org/10.1093/dote/doac038
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:150232834

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