Sökning: onr:"swepub:oai:DiVA.org:uu-490015" > Genetic loci and pr...
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001 | oai:DiVA.org:uu-490015 | |
003 | SwePub | |
008 | 221207s2022 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:151151706 | |
009 | oai:DiVA.org:du-41692 | |
009 | oai:lup.lub.lu.se:f928a6b3-f791-4a10-acf1-27d4afcbc5cf | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4900152 URI |
024 | 7 | a https://doi.org/10.1016/j.kint.2022.05.0212 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1511517062 URI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:du-416922 URI |
024 | 7 | a https://lup.lub.lu.se/record/f928a6b3-f791-4a10-acf1-27d4afcbc5cf2 URI |
040 | a (SwePub)uud (SwePub)kid (SwePub)dud (SwePub)lu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Gorski, Mathiasu Univ Regensburg, Dept Genet Epidemiol, Regensburg, Germany.;Univ Hosp Regensburg, Dept Nephrol, Regensburg, Germany.,University Hospital Regensburg,University of Regensburg4 aut |
245 | 1 0 | a Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies |
264 | 1 | b Elsevier,c 2022 |
338 | a electronic2 rdacarrier | |
520 | a Estimated glomerular filtration rate (eGFR) reflects kidney function. Progressive eGFR-decline can lead to kidney failure, necessitating dialysis or transplantation. Hundreds of loci from genome-wide association studies (GWAS) for eGFR help explain population cross section variability. Since the contribution of these or other loci to eGFR-decline remains largely unknown, we derived GWAS for annual eGFR-decline and meta-analyzed 62 longitudinal studies with eGFR assessed twice over time in all 343,339 individuals and in high-risk groups. We also explored different covariate adjustment. Twelve genomewide significant independent variants for eGFR-decline unadjusted or adjusted for eGFR- baseline (11 novel, one known for this phenotype), including nine variants robustly associated across models were identified. All loci for eGFR-decline were known for cross-sectional eGFR and thus distinguished a subgroup of eGFR loci. Seven of the nine variants showed variant- by-age interaction on eGFR cross section (further about 350,000 individuals), which linked genetic associations for eGFR-decline with agedependency of genetic cross- section associations. Clinically important were two to four-fold greater genetic effects on eGFR-decline in high-risk subgroups. Five variants associated also with chronic kidney disease progression mapped to genes with functional in- silico evidence (UMOD, SPATA7, GALNTL5, TPPP). An unfavorable versus favorable nine-variant genetic profile showed increased risk odds ratios of 1.35 for kidney failure (95% confidence intervals 1.03- 1.77) and 1.27 for acute kidney injury (95% confidence intervals 1.08-1.50) in over 2000 cases each, with matched controls). Thus, we provide a large data resource, genetic loci, and prioritized genes for kidney function decline, which help inform drug development pipelines revealing important insights into the age-dependency of kidney function genetics. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Medicinsk genetik0 (SwePub)301072 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Medical Genetics0 (SwePub)301072 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Urologi och njurmedicin0 (SwePub)302142 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Urology and Nephrology0 (SwePub)302142 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi0 (SwePub)303022 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Public Health, Global Health, Social Medicine and Epidemiology0 (SwePub)303022 hsv//eng |
653 | a acute kidney injury | |
653 | a chronic kidney disease | |
653 | a diabetes | |
653 | a gene expression | |
653 | a acute kidney injury | |
653 | a chronic kidney disease | |
653 | a diabetes | |
653 | a gene expression | |
700 | 1 | a Rasheed, Humairau Norwegian Univ Sci & Technol, KG Jebsen Ctr Genet Epidemiol, Dept Publ Hlth & Nursing, Fac Med & Hlth Sci,NTNU, Trondheim, Norway.;Univ Bristol, Bristol Med Sch, MRC Integrat Epidemiol Unit, Populat Hlth Sci, Bristol, Avon, England.4 aut |
700 | 1 | a Teumer, Alexanderu Univ Med Greifswald, Inst Community Med, Greifswald, Germany.;DZHK German Ctr Cardiovasc Res, Partner Site Greifswald, Greifswald, Germany.;Med Univ Bialystok, Dept Populat Med & Lifestyle Dis Prevent, Bialystok, Poland.4 aut |
700 | 1 | a Thomas, Laurent F.u Norwegian Univ Sci & Technol, KG Jebsen Ctr Genet Epidemiol, Dept Publ Hlth & Nursing, Fac Med & Hlth Sci,NTNU, Trondheim, Norway.;Norwegian Univ Sci & Technol, NTNU, Dept Clin & Mol Med, Trondheim, Norway.;Norwegian Univ Sci & Technol, BioCore Bioinformat Core Facil, Trondheim, Norway.4 aut |
700 | 1 | a Graham, Sarah E.u Univ Michigan, Dept Internal Med, Div Cardiol, Ann Arbor, MI 48109 USA.4 aut |
700 | 1 | a Sveinbjornsson, Gardaru deCODE Genet Amgen Inc, Reykjavik, Iceland.4 aut |
700 | 1 | a Winkler, Thomas W.4 aut |
700 | 1 | a Guenther, Felixu Univ Regensburg, Dept Genet Epidemiol, Regensburg, Germany.;Ludwig Maximilians Univ Munchen, Dept Stat, Stat Consulting Unit StaBLab, Munich, Germany.4 aut |
700 | 1 | a Stark, Klaus J.u Univ Regensburg, Dept Genet Epidemiol, Regensburg, Germany.4 aut |
700 | 1 | a Chai, Jin-Fangu Natl Univ Singapore, Saw Swee Hock Sch Publ Hlth, Singapore, Singapore.;Natl Univ Hlth Syst, Singapore, Singapore.4 aut |
700 | 1 | a Tayo, Bamidele O.u Loyola Univ Chicago, Dept Publ Hlth Sci, Maywood, IL USA.4 aut |
700 | 1 | a Wuttke, Matthiasu Univ Freiburg, Inst Genet Epidemiol, Dept Biometry Epidemiol & Med Bioinformat, Fac Med, Freiburg, Germany.;Univ Freiburg, Med Ctr, Freiburg, Germany.;Univ Freiburg, Div Renal, Dept Med 4, Fac Med, Freiburg, Germany.4 aut |
700 | 1 | a Li, Yongu Univ Freiburg, Inst Genet Epidemiol, Dept Biometry Epidemiol & Med Bioinformat, Fac Med, Freiburg, Germany.;Univ Freiburg, Med Ctr, Freiburg, Germany.4 aut |
700 | 1 | a Tin, Adrienneu Univ Mississippi, Med Ctr, Memory Impairment & Neurodegenerat Dementia MIND, Jackson, MS 39216 USA.;Univ Mississippi, Med Ctr, Dept Med, Div Nephrol, Jackson, MS 39216 USA.4 aut |
700 | 1 | a Ahluwalia, Tarunveer S.u Steno Diabet Ctr Copenhagen, Gentofte, Denmark.;Univ Copenhagen, Dept Biol, Bioinformat Ctr, Copenhagen, Denmark.4 aut |
700 | 1 | a Ärnlöv, Johan,d 1970-u Högskolan Dalarna,Karolinska Institutet,Medicinsk vetenskap,Karolinska Institutet, Stockholm4 aut0 (Swepub:du)jan |
700 | 1 | a Asvold, Bjorn Olavu Norwegian Univ Sci & Technol, KG Jebsen Ctr Genet Epidemiol, Dept Publ Hlth & Nursing, Fac Med & Hlth Sci,NTNU, Trondheim, Norway.;Trondheim Reg & Univ Hosp, St Olavs Hosp, Med Clin, Dept Endocrinol, Trondheim, Norway.4 aut |
700 | 1 | a Bakker, Stephan J. L.u Univ Groningen, Univ Med Ctr Groningen, Dept Internal Med, Div Nephrol, Groningen, Netherlands.4 aut |
700 | 1 | a Banas, Bernhardu Univ Hosp Regensburg, Dept Nephrol, Regensburg, Germany.4 aut |
700 | 1 | a Bansal, Nishau Univ Washington, Div Nephrol, Seattle, WA 98195 USA.;Univ Washington, Kidney Res Inst, Seattle, WA 98195 USA.4 aut |
700 | 1 | a Biggs, Mary L.u Univ Washington, Dept Med, Cardiovasc Hlth Res Unit, Seattle, WA USA.;Univ Washington, Dept Biostat, Seattle, WA 98195 USA.4 aut |
700 | 1 | a Biino, Ginevrau Natl Res Council Italy, Inst Mol Genet, Pavia, Italy.4 aut |
700 | 1 | a Bohnke, Michaelu Univ Michigan, Dept Biostat, Ann Arbor, MI 48109 USA.;Univ Michigan, Ctr Stat Genet, Ann Arbor, MI 48109 USA.4 aut |
700 | 1 | a Boerwinkle, Ericu Univ Texas Hlth Sci Ctr Houston, Ctr Human Genet, Houston, TX 77030 USA.4 aut |
700 | 1 | a Bottinger, Erwin P.u Icahn Sch Med Mt Sinai, Charles Bronfman Inst Personalized Med, New York, NY 10029 USA.;Hasso Plattner Inst, Digital Hlth Ctr, Potsdam, Germany.;Univ Potsdam, Potsdam, Germany.4 aut |
700 | 1 | a Brenner, Hermannu German Canc Res Ctr, Div Clin Epidemiol & Aging Res, Heidelberg, Germany.;Heidelberg Univ, Network Aging Res, Heidelberg, Germany.4 aut |
700 | 1 | a Brumpton, Benu Norwegian Univ Sci & Technol, KG Jebsen Ctr Genet Epidemiol, Dept Publ Hlth & Nursing, Fac Med & Hlth Sci,NTNU, Trondheim, Norway.;Univ Bristol, Bristol Med Sch, MRC Integrat Epidemiol Unit, Populat Hlth Sci, Bristol, Avon, England.;Trondheim Reg & Univ Hosp, St Olavs Hosp, Clin Thorac & Occupat Med, Trondheim, Norway.4 aut |
700 | 1 | a Carroll, Robert J.u Vanderbilt Univ, Med Ctr, Dept Biomed Informat, Nashville, TN USA.4 aut |
700 | 1 | a Chaker, Layalu Univ Med Ctr Rotterdam, Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands.;Univ Med Ctr Rotterdam, Erasmus MC, Dept Internal Med, Rotterdam, Netherlands.4 aut |
700 | 1 | a Chalmers, Johnu Univ New South Wales, George Inst Global Hlth, Sydney, NSW, Australia.4 aut |
700 | 1 | a Chee, Miao-Liu Singapore Natl Eye Ctr, Singapore Eye Res Inst, Singapore, Singapore.4 aut |
700 | 1 | a Chee, Miao-Lingu Singapore Natl Eye Ctr, Singapore Eye Res Inst, Singapore, Singapore.4 aut |
700 | 1 | a Cheng, Ching-Yuu Natl Univ Hlth Syst, Singapore, Singapore.;Singapore Natl Eye Ctr, Singapore Eye Res Inst, Singapore, Singapore.;Duke NUS Med Sch, Ophthalmol & Visual Sci Acad Clin Program Eye ACP, Singapore, Singapore.;Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Ophthalmol, Singapore, Singapore.4 aut |
700 | 1 | a Chu, Audrey Y.u Merck & Co Inc, Genet, Kenilworth, NJ USA.4 aut |
700 | 1 | a Ciullo, Marinau CNR, Inst Genet & Biophys Adriano Buzzati Traverso, Naples, Italy.;IRCCS Neuromed, Pozzilli, Italy.4 aut |
700 | 1 | a Cocca, Massimilianou IRCCS Burlo Garofolo, Inst Maternal & Child Hlth, Trieste, Italy.4 aut |
700 | 1 | a Cook, James P.u Univ Liverpool, Dept Hlth Data Sci, Liverpool, Merseyside, England.4 aut |
700 | 1 | a Coresh, Josefu Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA.4 aut |
700 | 1 | a Cusi, Danieleu Natl Res Council Italy, Inst Biomed Technol, Milan, Italy.;Bio4Dreams Business Nursery Life Sci, Milan, Italy.4 aut |
700 | 1 | a de Borst, Martin H.u Univ Groningen, Univ Med Ctr Groningen, Dept Internal Med, Div Nephrol, Groningen, Netherlands.4 aut |
700 | 1 | a Degenhardt, Fraukeu Christian Albrechts Univ Kiel, Inst Clin Mol Biol, Kiel, Germany.4 aut |
700 | 1 | a Eckardt, Kai-Uweu Charite Univ Med Berlin, Dept Nephrol & Med Intens Care, Berlin, Germany.;Friedrich Alexander Univ Erlangen Nurnberg FAU, Dept Nephrol & Hypertens, Erlangen, Germany.4 aut |
700 | 1 | a Endlich, Karlhansu DZHK German Ctr Cardiovasc Res, Partner Site Greifswald, Greifswald, Germany.;Univ Med Greifswald, Dept Anat & Cell Biol, Greifswald, Germany.4 aut |
700 | 1 | a Evans, Michele K.u NIA, Lab Epidemiol & Populat Sci, Intramural Res Program, US Natl Inst Hlth, Baltimore, MD 21224 USA.4 aut |
700 | 1 | a Feitosa, Mary F.u Washington Univ, Sch Med, Dept Genet, Div Stat Genom, St Louis, MO USA.4 aut |
700 | 1 | a Franke, Andreu Christian Albrechts Univ Kiel, Inst Clin Mol Biol, Kiel, Germany.4 aut |
700 | 1 | a Freitag-Wolf, Sandrau Univ Kiel, Univ Hosp Schleswig Holstein, Inst Med Informat & Stat, Kiel, Germany.4 aut |
700 | 1 | a Fuchsberger, Christianu Univ Michigan, Dept Biostat, Ann Arbor, MI 48109 USA.;Univ Michigan, Ctr Stat Genet, Ann Arbor, MI 48109 USA.;Univ Lubeck, Eurac Res, Inst Biomed, Bolzano, Italy.4 aut |
700 | 1 | a Gampawar, Piyushu Med Univ Graz, Ctr Mol Med, Inst Mol Biol & Biochem, Graz, Austria.4 aut |
700 | 1 | a Gansevoort, Ron T.u Univ Groningen, Univ Med Ctr Groningen, Dept Internal Med, Div Nephrol, Groningen, Netherlands.4 aut |
700 | 1 | a Ghanbari, Mohsenu Univ Med Ctr Rotterdam, Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands.;Mashhad Univ Med Sci, Sch Med, Dept Genet, Mashhad, Razavi Khorasan, Iran.4 aut |
700 | 1 | a Ghasemi, Saharu Univ Med Greifswald, Inst Community Med, Greifswald, Germany.;DZHK German Ctr Cardiovasc Res, Partner Site Greifswald, Greifswald, Germany.4 aut |
700 | 1 | a Giedraitis, Vilmantasu Uppsala universitet,Geriatrik,Molekylär geriatrik4 aut0 (Swepub:uu)vigie517 |
700 | 1 | a Gieger, Christianu German Res Ctr Environm Hlth, Helmholtz Zentrum Munchen, Res Unit Mol Epidemiol, Neuherberg, Germany.;German Res Ctr Environm Hlth, Helmholtz Zentrum Munchen, Inst Epidemiol, Neuherberg, Germany.;German Ctr Diabet Res DZD, Neuherberg, Germany.4 aut |
700 | 1 | a Gudbjartsson, Daniel F.u deCODE Genet Amgen Inc, Reykjavik, Iceland.;Univ Iceland, Iceland Sch Engn & Nat Sci, Reykjavik, Iceland.4 aut |
700 | 1 | a Hallan, Steinu Norwegian Univ Sci & Technol, NTNU, Dept Clin & Mol Med, Trondheim, Norway.;Trondheim Reg & Univ Hosp, St Olavs Hosp, Dept Nephrol, Trondheim, Norway.4 aut |
700 | 1 | a Hamet, Pavelu CHUM, Montreal Univ Hosp Res Ctr, Montreal, PQ, Canada.;Medpharmgene, Montreal, PQ, Canada.;CRCHUM, Montreal, PQ, Canada.4 aut |
700 | 1 | a Hishida, Asahiu Nagoya Univ, Grad Sch Med, Dept Prevent Med, Nagoya, Aichi, Japan.4 aut |
700 | 1 | a Ho, Kevinu Geisinger, KHRI, Danville, PA USA.;Geisinger, Dept Nephrol, Danville, PA USA.4 aut |
700 | 1 | a Hofer, Edithu Med Univ Graz, Clin Div Neurogeriatr, Dept Neurol, Graz, Austria.;Med Univ Graz, Inst Med Informat Stat & Documentat, Graz, Austria.4 aut |
700 | 1 | a Holleczek, Berndu German Canc Res Ctr, Div Clin Epidemiol & Aging Res, Heidelberg, Germany.4 aut |
700 | 1 | a Holm, Hilmau deCODE Genet Amgen Inc, Reykjavik, Iceland.4 aut |
700 | 1 | a Hoppmann, Anselmu Univ Freiburg, Inst Genet Epidemiol, Dept Biometry Epidemiol & Med Bioinformat, Fac Med, Freiburg, Germany.;Univ Freiburg, Med Ctr, Freiburg, Germany.4 aut |
700 | 1 | a Horn, Katrinu Univ Leipzig, Inst Med Informat Stat & Epidemiol, Leipzig, Germany.;Univ Leipzig, LIFE Res Ctr Civilizat Dis, Leipzig, Germany.4 aut |
700 | 1 | a Hutri-Kahonen, Ninau Tampere Univ Hosp, Dept Pediat, Tampere, Finland.;Tampere Univ, Dept Pediat, Fac Med & Hlth Technol, Tampere, Finland.4 aut |
700 | 1 | a Hveem, Kristianu Norwegian Univ Sci & Technol, KG Jebsen Ctr Genet Epidemiol, Dept Publ Hlth & Nursing, Fac Med & Hlth Sci,NTNU, Trondheim, Norway.4 aut |
700 | 1 | a Hwang, Shih-Jenu NHLBI, Framingham Heart Study, Framingham, MA USA.;NHLBI, Populat Sci Branch, Div Intramural Res, NIH, Bldg 10, Bethesda, MD 20892 USA.4 aut |
700 | 1 | a Ikram, M. Arfanu Univ Med Ctr Rotterdam, Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands.4 aut |
700 | 1 | a Josyula, Navya Shilpau Geisinger Res, Biomed & Translat Informat Inst, Rockville, MD USA.4 aut |
700 | 1 | a Jung, Bettinau Univ Hosp Regensburg, Dept Nephrol, Regensburg, Germany.;Kliniken Sudostbayern, Dept Nephrol & Rheumatol, Traunstein, Germany.;KfH Kidney Ctr Traunstein, Traunstein, Germany.4 aut |
700 | 1 | a Kahonen, Mikau Tampere Univ Hosp, Dept Clin Physiol, Tampere, Finland.;Tampere Univ, Finnish Cardiovasc Res Ctr Tampere, Fac Med & Hlth Technol, Dept Clin Physiol, Tampere, Finland.4 aut |
700 | 1 | a Karabegovic, Irmau Univ Med Ctr Rotterdam, Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands.4 aut |
700 | 1 | a Khor, Chiea-Chuenu Singapore Natl Eye Ctr, Singapore Eye Res Inst, Singapore, Singapore.;Agcy Sci Technol & Res, Genome Inst Singapore, Singapore, Singapore.4 aut |
700 | 1 | a Koenig, Wolfgangu Tech Univ Munich, Deutsch Herzzentrum Munchen, Munich, Germany.;DZHK German Ctr Cardiovasc Res, Partner Site Munich Heart Alliance, Munich, Germany.;Univ Ulm, Inst Epidemiol & Med Biometry, Ulm, Germany.4 aut |
700 | 1 | a Kramer, Hollyu Loyola Univ Chicago, Dept Publ Hlth Sci, Maywood, IL USA.;Loyola Univ, Div Nephrol & Hypertens, Chicago, IL 60611 USA.4 aut |
700 | 1 | a Kramer, Bernhard K.u Heidelberg Univ, Med Fac Mannheim, Dept Med Nephrol Hypertensiol Rheumatol Endocrino, Mannheim, Germany.4 aut |
700 | 1 | a Kuehnel, Brigitteu German Res Ctr Environm Hlth, Helmholtz Zentrum Munchen, Res Unit Mol Epidemiol, Neuherberg, Germany.4 aut |
700 | 1 | a Kuusisto, Johannau Kuopio Univ Hosp, Dept Med, Kuopio, Finland.;Univ Eastern Finland, Ctr Med & Clin Res, Sch Med, Kuopio, Finland.4 aut |
700 | 1 | a Laakso, Markkuu Kuopio Univ Hosp, Dept Med, Kuopio, Finland.;Univ Eastern Finland, Ctr Med & Clin Res, Sch Med, Kuopio, Finland.4 aut |
700 | 1 | a Lange, Leslie A.u Univ Colorado Denver Anschutz Med Campus, Sch Med, Div Biomed Informat & Personalized Med, Aurora, CO USA.4 aut |
700 | 1 | a Lehtimaki, Terhou Fimlab Labs, Dept Clin Chem, Tampere, Finland.;Tampere Univ, Dept Clin Chem, Fac Med & Hlth Technol, Finnish Cardiovasc Res Ctr Tampere, Tampere, Finland.4 aut |
700 | 1 | a Li, Manu Univ Utah, Dept Med, Div Nephrol & Hypertens, Salt Lake City, UT 84112 USA.4 aut |
700 | 1 | a Lieb, Wolfgangu Univ Kiel, Inst Epidemiol, Kiel, Germany.;Univ Kiel, Biobank Popgen, Kiel, Germany.4 aut |
700 | 1 | a Lind, Larsu Uppsala universitet,Klinisk epidemiologi4 aut0 (Swepub:uu)larslind |
700 | 1 | a Lindgren, Cecilia M.u Univ Oxford, Nuffield Dept Populat Hlth, Oxford, England.;Broad Inst MIT & Harvard, Cambridge, MA 02142 USA.;Univ Oxford, Wellcome Ctr Human Genet, Oxford, England.;Univ Oxford, Nuffield Dept Womens & Reprod Hlth, Womens Ctr, John Radcliffe Hosp, Level 3, Oxford, England.;Univ Oxford, Li Ka Shing Ctr Hlth Informat & Discovery, Big Data Inst, Oxford, England.4 aut |
700 | 1 | a Loos, Ruth J. F.u Icahn Sch Med Mt Sinai, Charles Bronfman Inst Personalized Med, New York, NY 10029 USA.;Icahn Sch Med Mt Sinai, Mindich Child Hlth & Dev Inst, New York, NY 10029 USA.4 aut |
700 | 1 | a Lukas, Mary Annu GlaxoSmithKline, Clin Sci, Albuquerque, NM USA.4 aut |
700 | 1 | a Lyytikainen, Leo-Pekkau Fimlab Labs, Dept Clin Chem, Tampere, Finland.;Tampere Univ, Dept Clin Chem, Fac Med & Hlth Technol, Finnish Cardiovasc Res Ctr Tampere, Tampere, Finland.4 aut |
700 | 1 | a Mahajan, Anubhau Univ Oxford, Wellcome Ctr Human Genet, Oxford, England.;Univ Oxford, Oxford Ctr Diabet Endocrinol & Metab, Oxford, England.4 aut |
700 | 1 | a Matias-Garcia, Pamela R.u German Res Ctr Environm Hlth, Helmholtz Zentrum Munchen, Res Unit Mol Epidemiol, Neuherberg, Germany.;German Res Ctr Environm Hlth, Helmholtz Zentrum Munchen, Inst Epidemiol, Neuherberg, Germany.;Tech Univ Munich, TUM Sch Med, Munich, Germany.4 aut |
700 | 1 | a Meisinger, Christau German Res Ctr Environm Hlth, Helmholtz Zentrum Munchen, Independent Res Grp Clin Epidemiol, Neuherberg, Germany.;Univ Augsburg, Univ Hosp Augsburg, Chair Epidemiol, Augsburg, Germany.4 aut |
700 | 1 | a Meitinger, Thomasu DZHK German Ctr Cardiovasc Res, Partner Site Munich Heart Alliance, Munich, Germany.;Helmholtz Zentrum Munchen, Inst Human Genet, Neuherberg, Germany.;Tech Univ Munich, Inst Human Genet, Munich, Germany.4 aut |
700 | 1 | a Melander, O.u Lund University,Lunds universitet,Kardiovaskulär forskning - hypertoni,Forskargrupper vid Lunds universitet,Cardiovascular Research - Hypertension,Lund University Research Groups,Diabetes - kardiovaskulär sjukdom,Diabetes - Cardiovascular Disease4 aut0 (Swepub:lu)endo-mor |
700 | 1 | a Milaneschi, Yuriu Vrije Univ, Amsterdam UMC, Dept Psychiat, Amsterdam Publ Hlth, Amsterdam, Netherlands.;Vrije Univ, Amsterdam UMC, Amsterdam Neurosci, Amsterdam, Netherlands.;GGZ inGeest, Amsterdam, Netherlands.4 aut |
700 | 1 | a Mishra, Pashupati P.u Fimlab Labs, Dept Clin Chem, Tampere, Finland.;Tampere Univ, Dept Clin Chem, Fac Med & Hlth Technol, Finnish Cardiovasc Res Ctr Tampere, Tampere, Finland.4 aut |
700 | 1 | a Mononen, Ninau Fimlab Labs, Dept Clin Chem, Tampere, Finland.;Tampere Univ, Dept Clin Chem, Fac Med & Hlth Technol, Finnish Cardiovasc Res Ctr Tampere, Tampere, Finland.4 aut |
700 | 1 | a Morris, Andrew P.u Univ Liverpool, Dept Hlth Data Sci, Liverpool, Merseyside, England.;Univ Oxford, Wellcome Ctr Human Genet, Oxford, England.;Univ Manchester, Ctr Musculoskeletal Res, Ctr Genet & Genom Versus Arthrit, Manchester, Lancs, England.4 aut |
700 | 1 | a Mychaleckyj, Josyf C.u Univ Virginia, Ctr Publ Hlth Genom, Charlottesville, VA USA.4 aut |
700 | 1 | a Nadkarni, Girish N.u Icahn Sch Med Mt Sinai, Charles Bronfman Inst Personalized Med, New York, NY 10029 USA.;Icahn Sch Med Mt Sinai, Dept Med, Div Nephrol, New York, NY 10029 USA.4 aut |
700 | 1 | a Naito, Marikou Nagoya Univ, Grad Sch Med, Dept Prevent Med, Nagoya, Aichi, Japan.;Hiroshima Univ, Grad Sch Biomed & Hlth Sci, Dept Oral Epidemiol, Hiroshima, Japan.4 aut |
700 | 1 | a Nakatochi, Masahirou Nagoya Univ, Grad Sch Med, Dept Integrated Hlth Sci, Publ Hlth Informat Unit, Nagoya, Aichi, Japan.4 aut |
700 | 1 | a Nalls, Mike A.u NIA, Neurogenet Lab, NIH, Bethesda, MD 20892 USA.;Data Tecn Int, Glen Echo, MD USA.4 aut |
700 | 1 | a Nauck, Matthiasu DZHK German Ctr Cardiovasc Res, Partner Site Greifswald, Greifswald, Germany.;Univ Med Greifswald, Inst Clin Chem & Lab Med, Greifswald, Germany.4 aut |
700 | 1 | a Nikus, Kjellu Tampere Univ Hosp, Ctr Heart, Dept Cardiol, Tampere, Finland.;Tampere Univ, Finnish Cardiovasc Res Ctr Tampere, Dept Cardiol, Fac Med & Hlth Technol, Tampere, Finland.4 aut |
700 | 1 | a Ning, Botingu Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA USA.4 aut |
700 | 1 | a Nolte, Ilja M.u Univ Groningen, Univ Med Ctr Groningen, Dept Epidemiol, Groningen, Netherlands.4 aut |
700 | 1 | a Nutile, Teresau CNR, Inst Genet & Biophys Adriano Buzzati Traverso, Naples, Italy.4 aut |
700 | 1 | a O'Donoghue, Michelle L.u Brigham & Womens Hosp, Div Cardiovasc, 75 Francis St, Boston, MA 02115 USA.;TIMI Study Grp, Boston, MA USA.4 aut |
700 | 1 | a O'Connell, Jeffreyu Univ Maryland, Sch Med, Baltimore, MD 21201 USA.4 aut |
700 | 1 | a Olafsson, Isleifuru Landspitali Univ Hosp, Dept Clin Biochem, Reykjavik, Iceland.4 aut |
700 | 1 | a Orho-Melander, Marjuu Lund Univ, Diabet & Cardiovasc Dis Genet Epidemiol, Dept Clin Sci Malmö, Malmö, Sweden.4 aut |
700 | 1 | a Parsa, Afshinu NIDDK, Div Kidney Urol & Hematol Dis, NIH, Bethesda, MD 20892 USA.;Univ Maryland, Sch Med, Dept Med, Baltimore, MD 21201 USA.4 aut |
700 | 1 | a Pendergrass, Sarah A.u Geisinger Res, Biomed & Translat Informat Inst, Danville, PA USA.4 aut |
700 | 1 | a Penninx, Brenda W. J. H.u Vrije Univ, Amsterdam UMC, Dept Psychiat, Amsterdam Publ Hlth, Amsterdam, Netherlands.;Vrije Univ, Amsterdam UMC, Amsterdam Neurosci, Amsterdam, Netherlands.;GGZ inGeest, Amsterdam, Netherlands.4 aut |
700 | 1 | a Pirastu, Mariou UOS Sassari, Natl Res Council Italy, Inst Genet & Biomed Res, Sassari, Italy.4 aut |
700 | 1 | a Preuss, Michael H.u Icahn Sch Med Mt Sinai, Charles Bronfman Inst Personalized Med, New York, NY 10029 USA.4 aut |
700 | 1 | a Psaty, Bruce M.u Univ Washington, Dept Hlth Serv, Dept Epidemiol, Cardiovasc Hlth Res Unit,Dept Med, Seattle, WA 98195 USA.4 aut |
700 | 1 | a Raffield, Laura M.u Univ N Carolina, Dept Genet, Chapel Hill, NC 27515 USA.4 aut |
700 | 1 | a Raitakari, Olli T.u Univ Turku, Ctr Populat Hlth Res, Turku, Finland.;Turku Univ Hosp, Turku, Finland.;Turku Univ Hosp, Dept Clin Physiol & Nucl Med, Turku, Finland.;Univ Turku, Res Ctr Appl & Prevent Cardiovasc Med, Turku, Finland.4 aut |
700 | 1 | a Rheinberger, Myriamu Univ Hosp Regensburg, Dept Nephrol, Regensburg, Germany.;Kliniken Sudostbayern, Dept Nephrol & Rheumatol, Traunstein, Germany.;KfH Kidney Ctr Traunstein, Traunstein, Germany.4 aut |
700 | 1 | a Rice, Kenneth M.u Univ Washington, Dept Biostat, Seattle, WA 98195 USA.4 aut |
700 | 1 | a Rizzi, Federicau Univ Milan, Dept Hlth Sci, Milan, Italy.;ePhood SRL, ePhood Sci Unit, Milan, Italy.4 aut |
700 | 1 | a Rosenkranz, Alexander R.u Med Univ Graz, Div Nephrol, Dept Internal Med, Graz, Austria.4 aut |
700 | 1 | a Rossing, Peteru Steno Diabet Ctr Copenhagen, Gentofte, Denmark.;Univ Copenhagen, Dept Clin Med, Copenhagen, Denmark.4 aut |
700 | 1 | a Rotter, Jerome I.u Harbor UCLA Med Ctr, Inst Translat Genom & Populat Sci, Dept Pediat, Lundquist Inst Biomed Innovat, Torrance, CA 90509 USA.4 aut |
700 | 1 | a Ruggiero, Danielau CNR, Inst Genet & Biophys Adriano Buzzati Traverso, Naples, Italy.;IRCCS Neuromed, Pozzilli, Italy.4 aut |
700 | 1 | a Ryan, Kathleen A.u Univ Maryland, Sch Med, Div Endocrinol Diabet & Nutr, Baltimore, MD 21201 USA.4 aut |
700 | 1 | a Sabanayagam, Charumathiu Singapore Natl Eye Ctr, Singapore Eye Res Inst, Singapore, Singapore.;Duke NUS Med Sch, Ophthalmol & Visual Sci Acad Clin Program Eye ACP, Singapore, Singapore.4 aut |
700 | 1 | a Salvi, Erikau Univ Milan, Dept Hlth Sci, Milan, Italy.;Fdn IRCCS Ist Neurol Carlo Besta, Neuroalgol Unit, Milan, Italy.4 aut |
700 | 1 | a Schmidt, Helenau Med Univ Graz, Ctr Mol Med, Inst Mol Biol & Biochem, Graz, Austria.4 aut |
700 | 1 | a Schmidt, Reinholdu Med Univ Graz, Clin Div Neurogeriatr, Dept Neurol, Graz, Austria.4 aut |
700 | 1 | a Scholz, Markusu Univ Leipzig, Inst Med Informat Stat & Epidemiol, Leipzig, Germany.;Univ Leipzig, LIFE Res Ctr Civilizat Dis, Leipzig, Germany.4 aut |
700 | 1 | a Schoettker, Benu German Canc Res Ctr, Div Clin Epidemiol & Aging Res, Heidelberg, Germany.;Heidelberg Univ, Network Aging Res, Heidelberg, Germany.4 aut |
700 | 1 | a Schulz, C.-A.u Lund University,Lunds universitet,Diabetes - kardiovaskulär sjukdom,Forskargrupper vid Lunds universitet,Diabetes - Cardiovascular Disease,Lund University Research Groups4 aut0 (Swepub:lu)med-csc |
700 | 1 | a Sedaghat, Sanazu Univ Med Ctr Rotterdam, Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands.;Northwestern Univ, Feinberg Sch Med, Dept Prevent Med, Chicago, IL 60611 USA.4 aut |
700 | 1 | a Shaffer, Christian M.u Vanderbilt Univ, Med Ctr, Dept Biomed Informat, Nashville, TN USA.4 aut |
700 | 1 | a Sieber, Karsten B.u GlaxoSmithKline, Human Genet, Collegeville, PA USA.4 aut |
700 | 1 | a Sim, Xuelingu Natl Univ Singapore, Saw Swee Hock Sch Publ Hlth, Singapore, Singapore.;Natl Univ Hlth Syst, Singapore, Singapore.4 aut |
700 | 1 | a Sims, Mariou Univ Mississippi, Med Ctr, Dept Med, Jackson, MS 39216 USA.4 aut |
700 | 1 | a Snieder, Haroldu Univ Groningen, Univ Med Ctr Groningen, Dept Epidemiol, Groningen, Netherlands.4 aut |
700 | 1 | a Stanzick, Kira J.u Univ Regensburg, Dept Genet Epidemiol, Regensburg, Germany.4 aut |
700 | 1 | a Thorsteinsdottir, Unnuru deCODE Genet Amgen Inc, Reykjavik, Iceland.;Univ Iceland, Sch Hlth Sci, Fac Med, Reykjavik, Iceland.4 aut |
700 | 1 | a Stocker, Hannahu German Canc Res Ctr, Div Clin Epidemiol & Aging Res, Heidelberg, Germany.;Heidelberg Univ, Network Aging Res, Heidelberg, Germany.4 aut |
700 | 1 | a Strauch, Konstantinu German Res Ctr Environm Hlth, Helmholtz Zentrum Munchen, Inst Genet Epidemiol, Neuherberg, Germany.;Ludwig Maximilians Univ Munchen, Chair Genet Epidemiol, IBE, Fac Med, Munich, Germany.;Johannes Gutenberg Univ Mainz, Univ Med Ctr, Inst Med Biostat Epidemiol & Informat, Mainz, Germany.4 aut |
700 | 1 | a Stringham, Heather M.u Univ Michigan, Dept Biostat, Ann Arbor, MI 48109 USA.;Univ Michigan, Ctr Stat Genet, Ann Arbor, MI 48109 USA.4 aut |
700 | 1 | a Sulem, Patricku deCODE Genet Amgen Inc, Reykjavik, Iceland.4 aut |
700 | 1 | a Szymczak, Silkeu Univ Kiel, Univ Hosp Schleswig Holstein, Inst Med Informat & Stat, Kiel, Germany.;Univ Lubeck, Univ Hosp Schleswig Holstein, Inst Med Biometry & Stat, Campus Lubeck, Lubeck, Germany.4 aut |
700 | 1 | a Taylor, Kent D.u Harbor UCLA Med Ctr, Inst Translat Genom & Populat Sci, Dept Pediat, Lundquist Inst Biomed Innovat, Torrance, CA 90509 USA.4 aut |
700 | 1 | a Thio, Chris H. L.u Univ Groningen, Univ Med Ctr Groningen, Dept Epidemiol, Groningen, Netherlands.4 aut |
700 | 1 | a Tremblay, Johanneu CHUM, Montreal Univ Hosp Res Ctr, Montreal, PQ, Canada.;Medpharmgene, Montreal, PQ, Canada.;CRCHUM, Montreal, PQ, Canada.4 aut |
700 | 1 | a Vaccargiu, Simonau UOS Sassari, Natl Res Council Italy, Inst Genet & Biomed Res, Sassari, Italy.4 aut |
700 | 1 | a van der Harst, Pimu Univ Groningen, Univ Med Ctr Groningen, Dept Cardiol, Groningen, Netherlands.;Univ Groningen, Univ Med Ctr Groningen, Dept Genet, Groningen, Netherlands.;Netherlands Heart Inst, Durrer Ctr Cardiovasc Res, Utrecht, Netherlands.4 aut |
700 | 1 | a van der Most, Peter J.u Univ Groningen, Univ Med Ctr Groningen, Dept Epidemiol, Groningen, Netherlands.4 aut |
700 | 1 | a Verweij, Nieku Univ Groningen, Univ Med Ctr Groningen, Dept Cardiol, Groningen, Netherlands.4 aut |
700 | 1 | a Volker, Uweu DZHK German Ctr Cardiovasc Res, Partner Site Greifswald, Greifswald, Germany.;Univ Med Greifswald, Interfac Inst Genet & Funct Genom, Greifswald, Germany.4 aut |
700 | 1 | a Wakai, Kenjiu Nagoya Univ, Grad Sch Med, Dept Prevent Med, Nagoya, Aichi, Japan.4 aut |
700 | 1 | a Waldenberger, Melanieu German Res Ctr Environm Hlth, Helmholtz Zentrum Munchen, Res Unit Mol Epidemiol, Neuherberg, Germany.;German Res Ctr Environm Hlth, Helmholtz Zentrum Munchen, Inst Epidemiol, Neuherberg, Germany.;DZHK German Ctr Cardiovasc Res, Partner Site Munich Heart Alliance, Munich, Germany.4 aut |
700 | 1 | a Wallentin, Lars,d 1943-u Uppsala universitet,Kardiologi,Uppsala kliniska forskningscentrum (UCR)4 aut0 (Swepub:uu)larswall |
700 | 1 | a Wallner, Stefanu Univ Hosp Regensburg, Inst Clin Chem & Lab Med, Regensburg, Germany.4 aut |
700 | 1 | a Wang, Judyu Washington Univ, Sch Med, Dept Genet, Div Stat Genom, St Louis, MO USA.4 aut |
700 | 1 | a Waterworth, Dawn M.u GlaxoSmithKline, Human Genet, Collegeville, PA USA.4 aut |
700 | 1 | a White, Harvey D.u Auckland City Hosp, Green Lane Cardiovasc Serv, Auckland, New Zealand.;Univ Auckland, Auckland, New Zealand.4 aut |
700 | 1 | a Willer, Cristen J.u Univ Michigan, Dept Internal Med, Div Cardiol, Ann Arbor, MI 48109 USA.;Univ Michigan, Dept Computat Med & Bioinformat, Ann Arbor, MI 48109 USA.;Univ Michigan, Dept Human Genet, Ann Arbor, MI 48109 USA.4 aut |
700 | 1 | a Wong, Tien-Yinu Singapore Natl Eye Ctr, Singapore Eye Res Inst, Singapore, Singapore.4 aut |
700 | 1 | a Woodward, Marku Univ New South Wales, George Inst Global Hlth, Sydney, NSW, Australia.;Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA.;Univ Oxford, George Inst Global Hlth, Oxford, England.4 aut |
700 | 1 | a Yang, Qiongu Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA USA.4 aut |
700 | 1 | a Yerges-Armstrong, Laura M.u GlaxoSmithKline, Human Genet, Collegeville, PA USA.4 aut |
700 | 1 | a Zimmermann, Martinau Univ Regensburg, Dept Genet Epidemiol, Regensburg, Germany.4 aut |
700 | 1 | a Zonderman, Alan B.u NIA, Lab Epidemiol & Populat Sci, Intramural Res Program, US Natl Inst Hlth, Baltimore, MD 21224 USA.4 aut |
700 | 1 | a Bergler, Tobiasu Univ Hosp Regensburg, Dept Nephrol, Regensburg, Germany.4 aut |
700 | 1 | a Stefansson, Kariu deCODE Genet Amgen Inc, Reykjavik, Iceland.;Univ Iceland, Sch Hlth Sci, Fac Med, Reykjavik, Iceland.4 aut |
700 | 1 | a Boger, Carsten A.u Univ Hosp Regensburg, Dept Nephrol, Regensburg, Germany.;Kliniken Sudostbayern, Dept Nephrol & Rheumatol, Traunstein, Germany.;KfH Kidney Ctr Traunstein, Traunstein, Germany.4 aut |
700 | 1 | a Pattaro, Cristianu Univ Lubeck, Eurac Res, Inst Biomed, Bolzano, Italy.4 aut |
700 | 1 | a Koettgen, Annau Univ Freiburg, Inst Genet Epidemiol, Dept Biometry Epidemiol & Med Bioinformat, Fac Med, Freiburg, Germany.;Univ Freiburg, Med Ctr, Freiburg, Germany.;Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA.4 aut |
700 | 1 | a Kronenberg, Florianu Med Univ Innsbruck, Inst Genet Epidemiol, Dept Genet & Pharmacol, Innsbruck, Austria.4 aut |
700 | 1 | a Heid, Iris M.u Univ Regensburg, Dept Genet Epidemiol, Regensburg, Germany.,University of Regensburg4 aut |
710 | 2 | a Univ Regensburg, Dept Genet Epidemiol, Regensburg, Germany.;Univ Hosp Regensburg, Dept Nephrol, Regensburg, Germany.b University Hospital Regensburg4 org |
710 | 2 | a Lifelines Cohort Study |
710 | 2 | a et al. |
773 | 0 | t Kidney Internationald : Elsevierg 102:3, s. 624-639q 102:3<624-639x 0085-2538x 1523-1755 |
856 | 4 | u https://doi.org/10.1016/j.kint.2022.05.021y Fulltext |
856 | 4 | u https://uu.diva-portal.org/smash/get/diva2:1716880/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
856 | 4 | u https://du.diva-portal.org/smash/get/diva2:1674090/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
856 | 4 | u http://dx.doi.org/10.1016/j.kint.2022.05.021x freey FULLTEXT |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-490015 |
856 | 4 8 | u https://doi.org/10.1016/j.kint.2022.05.021 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:151151706 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:du-41692 |
856 | 4 8 | u https://lup.lub.lu.se/record/f928a6b3-f791-4a10-acf1-27d4afcbc5cf |
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