Sökning: onr:"swepub:oai:DiVA.org:uu-512601" > Investigating the d...
Fältnamn | Indikatorer | Metadata |
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000 | 05067naa a2200469 4500 | |
001 | oai:DiVA.org:uu-512601 | |
003 | SwePub | |
008 | 230927s2023 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5126012 URI |
024 | 7 | a https://doi.org/10.1007/s00702-023-02616-72 DOI |
040 | a (SwePub)uu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a de Vries, Lyssau Katholieke Univ Leuven, Ctr Dev Psychiat, Dept Neurosci, Herestr 49,Box 1029, B-3000 Louvain, Belgium.;Univ Hosp Leuven, Louvain, Belgium.;Katholieke Univ Leuven, Leuven Autism Res LAuRes, Louvain, Belgium.4 aut |
245 | 1 0 | a Investigating the development of the autonomic nervous system in infancy through pupillometry |
264 | c 2023-03-12 | |
264 | 1 | b Springer,c 2023 |
338 | a print2 rdacarrier | |
520 | a We aim to investigate early developmental trajectories of the autonomic nervous system (ANS) as indexed by the pupillary light reflex (PLR) in infants with (i.e. preterm birth, feeding difficulties, or siblings of children with autism spectrum disorder) and without (controls) increased likelihood for atypical ANS development. We used eye-tracking to capture the PLR in 216 infants in a longitudinal follow-up study spanning 5 to 24 months of age, and linear mixed models to investigate effects of age and group on three PLR parameters: baseline pupil diameter, latency to constriction and relative constriction amplitude. An increase with age was found in baseline pupil diameter (F(3,273.21) = 13.15, p < 0.001, eta(2)(p) = 0.13), latency to constriction (F(3,326.41) =3.84, p = 0.010,eta(2)(p) = 0.03) and relative constriction amplitude(F(3,282.53) =3.70, p = 0.012,eta(2)(p)= 0.04). Group differences were found for baseline pupil diameter (F(3,235.91) = 9.40, p < 0.001,eta(2)(p) = 0.11), with larger diameter in preterms and siblings than in controls, and for latency to constriction (F(3,237.10) = 3.48, p = 0.017, eta(2)(p) = 0.04), with preterms having a longer latency than controls. The results align with previous evidence, with development over time that could be explained by ANS maturation. To better understand the cause of the group differences, further research in a larger sample is necessary, combining pupillometry with other measures to further validate its value. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Pediatrik0 (SwePub)302212 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Pediatrics0 (SwePub)302212 hsv//eng |
653 | a Pupillometry | |
653 | a Infant development | |
653 | a Autonomic nervous system | |
653 | a Autism spectrum disorder | |
653 | a Preterm birth | |
700 | 1 | a Amelynck, Steffieu Katholieke Univ Leuven, Ctr Dev Psychiat, Dept Neurosci, Herestr 49,Box 1029, B-3000 Louvain, Belgium.;Katholieke Univ Leuven, Leuven Autism Res LAuRes, Louvain, Belgium.4 aut |
700 | 1 | a Nyström, Pär,d 1975-u Uppsala universitet,Institutionen för psykologi4 aut0 (Swepub:uu)panys031 |
700 | 1 | a van Esch, Lotteu Katholieke Univ Leuven, Leuven Autism Res LAuRes, Louvain, Belgium.;Katholieke Univ Leuven, Fac Psychol & Educ Sci, Parenting & Special Educ Res Unit, Louvain, Belgium.4 aut |
700 | 1 | a Van Lierde, Thijsu Univ Ghent, Dept Expt Clin & Hlth Psychol, RIDDL Lab, Ghent, Belgium.4 aut |
700 | 1 | a Warreyn, Petrau Univ Ghent, Dept Expt Clin & Hlth Psychol, RIDDL Lab, Ghent, Belgium.4 aut |
700 | 1 | a Roeyers, Herbertu Univ Ghent, Dept Expt Clin & Hlth Psychol, RIDDL Lab, Ghent, Belgium.4 aut |
700 | 1 | a Noens, Ilseu Katholieke Univ Leuven, Leuven Autism Res LAuRes, Louvain, Belgium.;Katholieke Univ Leuven, Fac Psychol & Educ Sci, Parenting & Special Educ Res Unit, Louvain, Belgium.4 aut |
700 | 1 | a Naulaers, Gunnaru Univ Hosp Leuven, Louvain, Belgium.;Katholieke Univ Leuven, Dept Dev & Regenerat, Woman & Child, Louvain, Belgium.4 aut |
700 | 1 | a Boets, Bartu Katholieke Univ Leuven, Ctr Dev Psychiat, Dept Neurosci, Herestr 49,Box 1029, B-3000 Louvain, Belgium.;Katholieke Univ Leuven, Leuven Autism Res LAuRes, Louvain, Belgium.4 aut |
700 | 1 | a Steyaert, Jeanu Katholieke Univ Leuven, Ctr Dev Psychiat, Dept Neurosci, Herestr 49,Box 1029, B-3000 Louvain, Belgium.;Univ Hosp Leuven, Louvain, Belgium.;Katholieke Univ Leuven, Leuven Autism Res LAuRes, Louvain, Belgium.4 aut |
710 | 2 | a Katholieke Univ Leuven, Ctr Dev Psychiat, Dept Neurosci, Herestr 49,Box 1029, B-3000 Louvain, Belgium.;Univ Hosp Leuven, Louvain, Belgium.;Katholieke Univ Leuven, Leuven Autism Res LAuRes, Louvain, Belgium.b Katholieke Univ Leuven, Ctr Dev Psychiat, Dept Neurosci, Herestr 49,Box 1029, B-3000 Louvain, Belgium.;Katholieke Univ Leuven, Leuven Autism Res LAuRes, Louvain, Belgium.4 org |
773 | 0 | t Journal of neural transmissiond : Springerg 130, s. 723-734q 130<723-734x 0300-9564x 1435-1463 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-512601 |
856 | 4 8 | u https://doi.org/10.1007/s00702-023-02616-7 |
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