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Birth weight, ideal...
Birth weight, ideal cardiovascular health metrics in adulthood, and incident cardiovascular disease
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- Sun, Ying (författare)
- Shanghai Jiao Tong Univ, Shanghai Peoples Hosp 9, Sch Med, Inst Endocrinol & Metab,Dept Endocrinol & Metab, Shanghai 200011, Peoples R China.
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- Wang, Bin (författare)
- Shanghai Jiao Tong Univ, Shanghai Peoples Hosp 9, Sch Med, Inst Endocrinol & Metab,Dept Endocrinol & Metab, Shanghai 200011, Peoples R China.
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- Yu, Yuefeng (författare)
- Shanghai Jiao Tong Univ, Shanghai Peoples Hosp 9, Sch Med, Inst Endocrinol & Metab,Dept Endocrinol & Metab, Shanghai 200011, Peoples R China.
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- Wang, Yuying (författare)
- Shanghai Jiao Tong Univ, Shanghai Peoples Hosp 9, Sch Med, Inst Endocrinol & Metab,Dept Endocrinol & Metab, Shanghai 200011, Peoples R China.
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- Tan, Xiao (författare)
- Uppsala universitet,Lung- allergi- och sömnforskning,Zhejiang Univ, Sch Publ Hlth, Hangzhou 310058, Zhejiang, Peoples R China
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- Zhang, Jihui (författare)
- Guangzhou Med Univ, Affiliated Brain Hosp, Ctr Sleep & Circadian Med, Guangzhou 510370, Guangdong, Peoples R China.
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- Qi, Lu (författare)
- Tulane Univ, Sch Publ Hlth & Trop Med, Dept Epidemiol, New Orleans, LA 70118 USA.;Harvard TH Chan Sch Publ Hlth, Dept Nutr, Boston, MA 02138 USA.;Brigham & Womens Hosp, Dept Med, Channing Div Network Med, Boston, MA 02138 USA.;Harvard Med Sch, Boston, MA 02138 USA.
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- Lu, Yingli (författare)
- Shanghai Jiao Tong Univ, Shanghai Peoples Hosp 9, Sch Med, Inst Endocrinol & Metab,Dept Endocrinol & Metab, Shanghai 200011, Peoples R China.
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- Wang, Ningjian (författare)
- Shanghai Jiao Tong Univ, Shanghai Peoples Hosp 9, Sch Med, Inst Endocrinol & Metab,Dept Endocrinol & Metab, Shanghai 200011, Peoples R China.
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Shanghai Jiao Tong Univ, Shanghai Peoples Hosp 9, Sch Med, Inst Endocrinol & Metab,Dept Endocrinol & Metab, Shanghai 200011, Peoples R China Lung- allergi- och sömnforskning (creator_code:org_t)
- Wolters Kluwer, 2024
- 2024
- Engelska.
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Ingår i: Chinese Medical Journal. - : Wolters Kluwer. - 0366-6999. ; 137:10, s. 1160-1168
- Relaterad länk:
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Background: Prenatal and postnatal factors may have joint effects on cardiovascular health, and we aimed to assess the joint association of birth weight and ideal cardiovascular health metrics (ICVHMs) prospectively in adulthood with incident cardiovascular disease (CVD).Methods: In the UK Biobank, 227,833 participants with data on ICVHM components and birth weight and without CVD at baseline were included. The ICVHMs included smoking, body mass index, physical activity, diet information, total cholesterol, blood pressure, and hemoglobin A1c. The Cox proportional hazards model was used to estimate the hazard ratios (HRs) and 95% confidence intervals (CIs) in men and women.Results: Over a median follow-up period of 13.0 years (2,831,236 person-years), we documented 17,477 patients with incident CVD. Compared with participants with birth weights of 2.5–4.0 kg, the HRs (95% CIs) of CVD among those with low birth weights was 1.08 (1.00–1.16) in men and 1.23 (1.16–1.31) in women. The association between having a birth weight <2.5 kg and CVD risk in men was more prominent for those aged <50 years than for those of older age (P for interaction = 0.026). Lower birth weight and non-ideal cardiovascular health metrics were jointly related to an increased risk of CVD. Participants with birth weights <2.5 kg and ICVHMs score 0–1 had the highest risk of incident CVD (HR [95% CI]: 3.93 [3.01–5.13] in men; 4.24 [3.33–5.40] in women). The joint effect (HR [95% CI]: 1.36 [1.17–1.58]) could be decomposed into 24.7% (95% CI: 15.0%–34.4%) for a lower birth weight, 64.7% (95% CI: 56.7%–72.6%) for a lower ICVHM score, and 10.6% (95% CI: 2.7%–18.6%) for their additive interaction in women.Conclusions: Birth weight and ICVHMs were jointly related to CVD risk. Attaining a normal birth weight and ideal ICVHMs may reduce the risk of CVD, and a simultaneous improvement of both prenatal and postnatal factors could further prevent additional cases in women.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- Birth weight
- Health metrics
- Cardiovascular disease
- Adult
- Stroke
- Coronary heart disease
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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