Biomechanical, histological and ultrastructural analyses of laser micro- and nano-structured titanium implant after 6 months in rabbit.

• Short-term, experimental studies of partly laser-modified implants with nano-scale surface topographical features have recently shown a considerable increase in the biomechanical anchorage to bone. The aim of this study is to evaluate the biomechanical and bone-bonding ability of partly laser-modified implants compared with machined implants after a healing period of 6 months in a rabbit model. The results showed a 170% increase in removal torque. Histology and scanning electron microscopy demonstrated osseointegration for both implant types, but also revealed a different fracture pattern at the interface and in the bone. Transmission electron microscopy and chemical analysis showed coalescence between mineralized tissue and the nano-structured surface of the laser modified implant. Taken together, the results indicate that nano-structured surfaces promote in vivo long-term bone bonding and interface strength.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Medicinsk bioteknologi -- Biomaterialvetenskap (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Medical Biotechnology -- Biomaterials Science (hsv//eng)

Keyword

Animals

Coated Materials

Biocompatible

chemistry

metabolism

Female

Femur

anatomy & histology

metabolism

Implants

Experimental

Lasers

Materials Testing

Microscopy

Electron

Osseointegration

Rabbits

Stress

Mechanical

Surface Properties

Tibia

anatomy & histology

metabolism

Titanium

chemistry

metabolism

Publication and Content Type

ref (subject category)

art (subject category)