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High-Resolution Pro...
High-Resolution Protein Structure Determination by Serial Femtosecond Crystallography
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Boutet, S. (author)
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Lomb, L. (author)
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Williams, G. J. (author)
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show more...
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Barends, T. R. M. (author)
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Aquila, A. (author)
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Doak, R. B. (author)
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Weierstall, U. (author)
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Deponte, D. P. (author)
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Steinbrener, J. (author)
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Shoeman, R. L. (author)
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Seibert, M Marvin (author)
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Barty, A. (author)
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White, T. A. (author)
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Kassemeyer, S. (author)
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Kirian, R. A. (author)
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Seibert, M. M. (author)
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Montanez, P. A. (author)
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Kenney, C. (author)
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Herbst, R. (author)
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Hart, P. (author)
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Pines, J. (author)
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Haller, G. (author)
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Gruner, S. M. (author)
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Philipp, H. T. (author)
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Tate, M. W. (author)
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Hromalik, M. (author)
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Koerner, L. J. (author)
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van Bakel, N. (author)
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Morse, J. (author)
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Ghonsalves, W. (author)
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- Arnlund, David (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kemi och molekylärbiologi,Department of Chemistry and Molecular Biology
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Bogan, M. J. (author)
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- Caleman, Carl (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kemi och molekylärbiologi,Department of Chemistry and Molecular Biology
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Fromme, R. (author)
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Hampton, C. Y. (author)
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Hunter, M. S. (author)
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- Johansson, Linda C, 1983 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kemi och molekylärbiologi,Department of Chemistry and Molecular Biology
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- Katona, Gergely, 1975 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kemi och molekylärbiologi,Department of Chemistry and Molecular Biology
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Kupitz, C. (author)
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Liang, M. N. (author)
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Martin, A. V. (author)
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Nass, K. (author)
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Redecke, L. (author)
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Stellato, F. (author)
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- Timneanu, Nicusor (author)
- Uppsala universitet,Molekylär biofysik
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Wang, D. J. (author)
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Zatsepin, N. A. (author)
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Schafer, D. (author)
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Defever, J. (author)
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- Neutze, Richard, 1969 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kemi och molekylärbiologi,Department of Chemistry and Molecular Biology
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Fromme, P. (author)
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Spence, J. C. H. (author)
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Chapman, H. N. (author)
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Schlichting, I. (author)
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(creator_code:org_t)
- American Association for the Advancement of Science (AAAS), 2012
- 2012
- English.
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In: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 337:6092, s. 362-364
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https://gup.ub.gu.se... (primary) (free)
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http://bib-pubdb1.de...
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
Subject headings
Close
- Structure determination of proteins and other macromolecules has historically required the growth of high-quality crystals sufficiently large to diffract x-rays efficiently while withstanding radiation damage. We applied serial femtosecond crystallography (SFX) using an x-ray free-electron laser (XFEL) to obtain high-resolution structural information from microcrystals (less than 1 micrometer by 1 micrometer by 3 micrometers) of the well-characterized model protein lysozyme. The agreement with synchrotron data demonstrates the immediate relevance of SFX for analyzing the structure of the large group of difficult-to-crystallize molecules.
Subject headings
- NATURVETENSKAP -- Biologi -- Biokemi och molekylärbiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Biochemistry and Molecular Biology (hsv//eng)
- TEKNIK OCH TEKNOLOGIER -- Nanoteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Nano-technology (hsv//eng)
- NATURVETENSKAP -- Biologi -- Strukturbiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Structural Biology (hsv//eng)
Keyword
- diffraction data
- nanocrystallography
- lysozyme
- crystals
Publication and Content Type
- ref (subject category)
- art (subject category)
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Science
(Search for host publication in LIBRIS)
To the university's database
- By the author/editor
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Boutet, S.
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Lomb, L.
-
Williams, G. J.
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Barends, T. R. M ...
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Aquila, A.
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Doak, R. B.
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show more...
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Weierstall, U.
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Deponte, D. P.
-
Steinbrener, J.
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Shoeman, R. L.
-
Seibert, M Marvi ...
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Barty, A.
-
White, T. A.
-
Kassemeyer, S.
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Kirian, R. A.
-
Seibert, M. M.
-
Montanez, P. A.
-
Kenney, C.
-
Herbst, R.
-
Hart, P.
-
Pines, J.
-
Haller, G.
-
Gruner, S. M.
-
Philipp, H. T.
-
Tate, M. W.
-
Hromalik, M.
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Koerner, L. J.
-
van Bakel, N.
-
Morse, J.
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Ghonsalves, W.
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Arnlund, David
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Bogan, M. J.
-
Caleman, Carl
-
Fromme, R.
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Hampton, C. Y.
-
Hunter, M. S.
-
Johansson, Linda ...
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Katona, Gergely, ...
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Kupitz, C.
-
Liang, M. N.
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Martin, A. V.
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Nass, K.
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Redecke, L.
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Stellato, F.
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Timneanu, Nicuso ...
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Wang, D. J.
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Zatsepin, N. A.
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Schafer, D.
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Defever, J.
-
Neutze, Richard, ...
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Fromme, P.
-
Spence, J. C. H.
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Chapman, H. N.
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Schlichting, I.
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show less...
- About the subject
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Biological Scien ...
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and Biochemistry and ...
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- ENGINEERING AND TECHNOLOGY
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ENGINEERING AND ...
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and Nano technology
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Biological Scien ...
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and Structural Biolo ...
- Articles in the publication
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Science
- By the university
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University of Gothenburg
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Uppsala University