The Model Muddle: In Search of Tumor Growth Laws

Gerlee, Philip,1980Gothenburg University,Göteborgs universitet,Institutionen för matematiska vetenskaper, matematik,Sahlgrenska Cancer Center,Department of Mathematical Sciences, Mathematics,University of Gothenburg,Chalmers tekniska högskola,Chalmers University of Technology (author)

In this article, we will trace the historical development of tumor growth laws, which in a quantitative fashion describe the increase in tumor mass/volume over time. These models are usually formulated in terms of differential equations that relate the growth rate of the tumor to its current state and range from the simple one-parameter exponential growth model to more advanced models that contain a large number of parameters. Understanding the assumptions and consequences of such models is important, as they often underpin more complex models of tumor growth. The conclusion of this brief survey is that although much improvement has occurred over the last century, more effort and new models are required if we are to understand the intricacies of tumor growth.

Göteborgs universitetInstitutionen för matematiska vetenskaper, matematik (creator_code:org_t)

In:Cancer Research: American Association for Cancer Research (AACR)73:8, s. 2407-24110008-54721538-7445

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Cancer and Oncol ...

By the university: University of Gothenburg; Chalmers University of Technology

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