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Virulence factors o...
Virulence factors of Staphylococcus aureus strains causing infective endocarditis--a comparison with strains from skin infections.
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- Hogevik, Harriet (author)
- Uppsala universitet,Gothenburg University,Göteborgs universitet,Institutionen för invärtesmedicin, Avdelningen för infektionssjukdomar,Institute of Internal Medicine, Dept of Infectious Diseases,Institutionen för medicinsk och fysiologisk kemi
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Söderquist, B (author)
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Tung, H S (author)
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- Olaison, Lars, 1949 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för invärtesmedicin, Avdelningen för infektionssjukdomar,Institute of Internal Medicine, Dept of Infectious Diseases
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- Westberg, A (author)
- Uppsala universitet,Institutionen för medicinsk och fysiologisk kemi
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- Rydén, C (author)
- Uppsala universitet,Infektionssjukdomar,Friman, infektion
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Tarkowski, A (author)
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- Andersson, Rune, 1951 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för invärtesmedicin, Avdelningen för infektionssjukdomar,Institute of Internal Medicine, Dept of Infectious Diseases
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(creator_code:org_t)
- Wiley, 1998
- 1998
- English.
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In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. - : Wiley. - 0903-4641 .- 0903-465X .- 1600-5503 .- 1600-0463. ; 106:9, s. 901-8
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Abstract
Subject headings
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- The objective was to study potential bacterial virulence factors in S. aureus endocarditis. S. aureus strains isolated from patients with well-classified episodes of infective endocarditis (IE) (n=26) were compared with control S. aureus strains from consecutive patients with skin infections (n=30). The potential virulence factors studied were Staphylococcal enterotoxin A-D (SEA, SEB, SEC, SED) and toxic shock syndrome toxin-1 (TSST-1) production and binding capacity to the extracellular matrix proteins: fibronectin, collagen type I, collagen type II and bone sialoprotein (BSP). None of the potential virulence factors studied was more prevalent among the IE strains. BSP binding was more often found in the control group with skin infections. Endocarditis patients with previous damage of the heart valves were more often infected by strains not producing any enterotoxin. No correlation was found between the potential bacterial virulence factors studied and IE. Concerning the toxins known to act as superantigens (SEA-E and TSST-1), the tendencies in this and other studies indicate that a larger study group might identify them as pathogenic factors in a subgroup of staphylococcal endocarditis.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Infektionsmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Infectious Medicine (hsv//eng)
Keyword
- Adolescent
- Adult
- Aged
- Aged
- 80 and over
- Bacterial Toxins
- Child
- Preschool
- Collagen
- metabolism
- Endocarditis
- Bacterial
- microbiology
- Enterotoxins
- analysis
- Female
- Fibronectins
- metabolism
- Humans
- Infant
- Integrin-Binding Sialoprotein
- Male
- Middle Aged
- Sialoglycoproteins
- metabolism
- Skin
- microbiology
- Staphylococcal Infections
- microbiology
- Staphylococcal Skin Infections
- microbiology
- Staphylococcus aureus
- chemistry
- metabolism
- pathogenicity
- Superantigens
- Virulence
- infective endocarditis
- MEDICINE
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Hogevik, Harriet
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Söderquist, B
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Tung, H S
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Olaison, Lars, 1 ...
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Westberg, A
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Rydén, C
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show more...
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Tarkowski, A
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Andersson, Rune, ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Infectious Medic ...
- Articles in the publication
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APMIS : acta pat ...
- By the university
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University of Gothenburg
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Uppsala University