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Efficacy and safety...
Efficacy and safety of oral misoprostol versus transvaginal balloon catheter for labor induction: An observational study within the SWEdish Postterm Induction Study (SWEPIS)
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- Alkmark, Mårten, 1973 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för obstetrik och gynekologi,Institute of Clinical Sciences, Department of Obstetrics and Gynecology,Univ Gothenburg, Ctr Perinatal Med & Hlth, Inst Clin Sci, Dept Obstet & Gynecol, Gothenburg, Sweden; Reg Västra Götaland, Dept Obstet & Gynecol, Sahlgrenska Univ Hosp, Gothenburg, Sweden
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- Carlsson, Ylva, 1975 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för obstetrik och gynekologi,Institute of Clinical Sciences, Department of Obstetrics and Gynecology,Univ Gothenburg, Ctr Perinatal Med & Hlth, Inst Clin Sci, Dept Obstet & Gynecol, Gothenburg, Sweden; Reg Västra Götaland, Dept Obstet & Gynecol, Sahlgrenska Univ Hosp, Gothenburg, Sweden
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- Wendel, S. B. (författare)
- Karolinska Inst, Danderyd Hosp, Dept Clin Sci, Stockholm, Sweden,Karolinska Inst, Karolinska Univ Hosp, Dept Womens & Childrens Hlth, Stockholm, Sweden
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- Elden, Helen, 1959 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för vårdvetenskap och hälsa,Institute of Health and Care Sciences,Reg Västra Götaland, Dept Obstet & Gynecol, Sahlgrenska Univ Hosp, Gothenburg, Sweden; Univ Gothenburg, Sahlgrenska Acad, Inst Hlth & Care Sci, Gothenburg, Sweden
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- Fadl, H. (författare)
- Örebro Univ, Fac Med & Hlth, Dept Obstet & Gynecol, Örebro, Sweden
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- Jonsson, Maria, 1966- (författare)
- Uppsala universitet,Klinisk obstetrik
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- Ladfors, Lars, 1951 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för obstetrik och gynekologi,Institute of Clinical Sciences, Department of Obstetrics and Gynecology,Univ Gothenburg, Ctr Perinatal Med & Hlth, Inst Clin Sci, Dept Obstet & Gynecol, Gothenburg, Sweden; Reg Västra Götaland, Dept Obstet & Gynecol, Sahlgrenska Univ Hosp, Gothenburg, Sweden
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Saltvedt, S. (författare)
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- Sengpiel, Verena, 1977 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för obstetrik och gynekologi,Institute of Clinical Sciences, Department of Obstetrics and Gynecology,Univ Gothenburg, Ctr Perinatal Med & Hlth, Inst Clin Sci, Dept Obstet & Gynecol, Gothenburg, Sweden; Reg Västra Götaland, Dept Obstet & Gynecol, Sahlgrenska Univ Hosp, Gothenburg, Sweden
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- Wessberg, A. (författare)
- Reg Västra Götaland, Dept Obstet & Gynecol, Sahlgrenska Univ Hosp, Gothenburg, Sweden
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- Wikström, Anna-Karin, 1965- (författare)
- Uppsala universitet,Klinisk obstetrik
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- Hagberg, Henrik, 1955 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för obstetrik och gynekologi,Institute of Clinical Sciences, Department of Obstetrics and Gynecology,Univ Gothenburg, Ctr Perinatal Med & Hlth, Inst Clin Sci, Dept Obstet & Gynecol, Gothenburg, Sweden; Reg Västra Götaland, Dept Obstet & Gynecol, Sahlgrenska Univ Hosp, Gothenburg, Sweden
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- Wennerholm, Ulla-Britt, 1948 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för obstetrik och gynekologi,Institute of Clinical Sciences, Department of Obstetrics and Gynecology,Univ Gothenburg, Ctr Perinatal Med & Hlth, Inst Clin Sci, Dept Obstet & Gynecol, Gothenburg, Sweden; Reg Västra Götaland, Dept Obstet & Gynecol, Sahlgrenska Univ Hosp, Gothenburg, Sweden
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(creator_code:org_t)
- 2021-05-02
- 2021
- Engelska.
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Ingår i: Acta Obstetricia et Gynecologica Scandinavica. - : Wiley. - 0001-6349 .- 1600-0412. ; 100:8, s. 1463-1477
- Relaterad länk:
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https://onlinelibrar...
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https://doi.org/10.1...
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https://uu.diva-port... (primary) (Raw object)
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- Introduction Induction of labor is increasing. A common indication for induction of labor is late term and postterm pregnancy at 41 weeks or more. We aimed to evaluate if there are any differences regarding efficacy, safety, and women's childbirth experience between oral misoprostol and transvaginal balloon catheter for cervical ripening in women with a low-risk singleton pregnancy and induction of labor at 41(+0) to 42(+0 to 1) weeks of gestation. Material and methods In this observational study, based on data from the Swedish Postterm Induction Study (SWEPIS), a multicenter randomized controlled trial, a total of 1213 women with a low-risk singleton pregnancy at 41 to 42 weeks of gestation were induced with oral misoprostol (n = 744) or transvaginal balloon catheter (n = 469) at 15 Swedish delivery hospitals. The primary efficacy outcome was vaginal delivery within 24 h and primary safety outcomes were neonatal and maternal composite adverse outcomes. Secondary outcomes included time to vaginal delivery and mode of delivery. Women's childbirth experience was assessed with the Childbirth Experience Questionnaire (CEQ 2.0) and visual analog scale. We present crude and adjusted mean differences and relative risks (RR) with 95% CI. Adjustment was performed for a propensity score based on delivery hospital and baseline characteristics including Bishop score. Results Vaginal delivery within 24 h was significantly lower in the misoprostol group compared with the balloon catheter group (46.5% [346/744] versus 62.7% [294/469]; adjusted RR 0.76 95% CI 0.640.89]). Primary neonatal and maternal safety outcomes did not differ between groups (neonatal composite 3.5% [36/744] vs 3.2% [15/469]; adjusted RR 0.77 [95% CI 0.31-1.89]; maternal composite 2.3% [17/744] versus 1.9% [9/469]; adjusted RR 1.70 [95% CI 0.58-4.97]). Adjusted mean time to vaginal delivery was increased by 3.8 h (95% CI 1.3-6.2 h) in the misoprostol group. Non-operative vaginal delivery and cesarean delivery rates did not differ. Women's childbirth experience was positive overall and similar in both groups. Conclusion Induction of labor with oral misoprostol compared with a transvaginal balloon catheter was associated with a lower probability of vaginal delivery within 24 h and a longer time to vaginal delivery. However, primary safety outcomes, non-operative vaginal delivery, and women's childbirth experience were similar in both groups. Therefore, both methods can be recommended in women with low-risk postdate pregnancies.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Reproduktionsmedicin och gynekologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Obstetrics, Gynaecology and Reproductive Medicine (hsv//eng)
Nyckelord
- humans
- labor induction
- misoprostol
- mothers
- psychology
- pregnancy
- outcome
- pregnancy prolonged
- randomized controlled-trial
- foley catheter
- expectant management
- womens experiences
- multicenter
- pregnancy
- childbirth
- gestation
- register
- outcomes
- Obstetrics & Gynecology
- humans
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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- Av författaren/redakt...
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Alkmark, Mårten, ...
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Carlsson, Ylva, ...
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Wendel, S. B.
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Elden, Helen, 19 ...
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Fadl, H.
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Jonsson, Maria, ...
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Ladfors, Lars, 1 ...
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Saltvedt, S.
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Sengpiel, Verena ...
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Wessberg, A.
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Wikström, Anna-K ...
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Hagberg, Henrik, ...
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Wennerholm, Ulla ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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Acta Obstetricia ...
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Göteborgs universitet
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Uppsala universitet