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Brain diffusion MRI...
Brain diffusion MRI with multiplexed sensitivity encoding for reduced distortion in a pediatric patient population
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- Johansson, Jens (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för radiologi,Institute of Clinical Sciences, Department of Radiology
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- Lagerstrand, Kerstin M (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper,Institute of Clinical Sciences
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Ivarsson, L. (författare)
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Svensson, P. A. (författare)
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- Hebelka, Hanna, 1977 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för radiologi,Institute of Clinical Sciences, Department of Radiology
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- Maier, Stephan E, 1959 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för radiologi,Institute of Clinical Sciences, Department of Radiology
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(creator_code:org_t)
- Elsevier BV, 2022
- 2022
- Engelska.
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Ingår i: Magnetic Resonance Imaging. - : Elsevier BV. - 0730-725X. ; 87, s. 97-103
- Relaterad länk:
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https://doi.org/10.1...
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Background: Diffusion-weighted imaging (DWI) is a valuable tool for routine imaging of the pediatric brain. However, the commonly used single-shot (ss) echo-planar imaging (EPI) DWI sequence is prone to geometric distortions and T2*-blurring. This study aimed to investigate in a pediatric population the benefits of using multiplexed sensitivity-encoding (MUSE) without and with reversed polarity gradients (RPG) instead. Methods: This retrospective study compared image quality, geometric distortions, and diffusion values between three different approaches for DWI (ssEPI, MUSE, and RPG-MUSE) in 14 patients (median age = 4 (0.6–15) years, 11 males). Distortion levels were quantified and compared in two brain regions, i.e., the brain stem and the temporal lobes, using the Dice Coefficient and the Hausdorff Distance, with T2-weighted images as reference. Expected geometrical distortion was further evaluated by comparing the effective echo spacing between the DWI sequences. Apparent diffusion coefficient (ADC) values were determined in the genu of the corpus callosum and the optic nerves. Two raters graded overall image quality and image distortions on a Likert scale. Results: Distortion levels assessed with Dice coefficient and Hausdorff distance were significantly lower for MUSE (p < 0.05) and RPG-MUSE (p < 0.01) compared to ssEPI. No significant difference in ADC values was observed between methods. The RPG-MUSE method was graded by one rater as significantly higher in overall image quality than ssEPI (p < 0.05) and by both raters as significantly lower in levels of image distortions than both MUSE (p < 0.05) and ssEPI (p < 0.05). These results were in agreement with the reduced effective echo spacing was that was attained with MUSE and RPG-MUSE. Conclusion: For imaging of the pediatric brain, MUSE and even more so RPG-MUSE offers both improved geometric fidelity and image quality compared to ssEPI. © 2022 The Authors
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)
Nyckelord
- Diffusion-weighted imaging
- Echo-planar imaging
- Geometric distortion
- Multiplexed sensitivity-encoding
- Pediatric brain
- Reverse polarity gradients
- apparent diffusion coefficient
- article
- brain region
- brain stem
- child
- clinical article
- controlled study
- diffusion weighted imaging
- echo planar imaging
- genu (corpus callosum)
- human
- image quality
- intermethod comparison
- Likert scale
- male
- optic nerve
- pediatric patient
- preschool child
- quantitative analysis
- retrospective study
- temporal lobe
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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