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Astatine-211 based radionuclide therapy: Current clinical trial landscape
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- Albertsson, Per, 1964 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för onkologi,Institute of Clinical Sciences, Department of Oncology
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- Bäck, Tom, 1964 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för medicinsk strålningsvetenskap,Institute of Clinical Sciences, Department of Medical Radiation Sciences
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- Bergmark, Karin, 1962 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för onkologi,Institute of Clinical Sciences, Department of Oncology
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- Smerud, K. (author)
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- (creator_code:org_t)
- 2023-01-06
- 2023
- English.
- In: Frontiers in Medicine. - : Frontiers Media SA. - 2296-858X. ; 9
- Journal article (peer-reviewed)
Abstract
Subject headings
Close
- Astatine-211 (At-211) has physical properties that make it one of the top candidates for use as a radiation source for alpha particle-based radionuclide therapy, also referred to as targeted alpha therapy (TAT). Here, we summarize the main results of the completed clinical trials, further describe ongoing trials, and discuss future prospects.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)
Keyword
- targeted alpha therapy
- alpha particle
- astatine-211
- radionuclide
- human
- clinical trial
- chimeric monoclonal-antibody
- growing ovarian-cancer
- long-term
- survival
- pretargeted radioimmunotherapy
- alpha-radioimmunotherapy
- nude-mice
- phase-i
- intraperitoneal radioimmunotherapy
- peritoneal
- carcinomatosis
- anti-cd45 antibody
- General & Internal Medicine
Publication and Content Type
- ref (subject category)
- art (subject category)
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- Palm, Stig, 1964
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- University of Gothenburg
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