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Impaired artery ela...
Impaired artery elasticity predicts cardiovascular morbidity and mortality- A longitudinal study in the Vara-Skövde Cohort.
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- Szaló, Gábor, 1982 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine,Univ Gothenburg, Sweden,Sahlgrenska Academy
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- Hellgren, Margareta, 1955 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine,Univ Gothenburg, Sweden; Skaraborg Inst, Sweden,Skaraborg Institute for Research and Development,Sahlgrenska Academy
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- Allison, Matthew (author)
- Univ Calif San Diego, CA USA,University of California, San Diego
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- Li, Ying (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine,Univ Gothenburg, Sweden,Sahlgrenska Academy
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- Råstam, Lennart (author)
- Lund University,Lunds universitet,Allmänmedicin och samhällsmedicin,Forskargrupper vid Lunds universitet,Family Medicine and Community Medicine,Lund University Research Groups
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- Rådholm, Karin (author)
- Linköping University,Linköpings universitet,Avdelningen för prevention, rehabilitering och nära vård,Medicinska fakulteten,Region Östergötland, Vårdcentralen Kärna
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- Bollano, Entela, 1970 (author)
- Sahlgrens Univ Hosp, Sweden,Sahlgrenska University Hospital
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- Duprez, Daniel A (author)
- Univ Minnesota, MN 55455 USA,University of Minnesota
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- Jacobs, David R (author)
- Univ Minnesota, MN USA,University of Minnesota
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- Lindblad, Ulf, 1950 (author)
- University of Gothenburg,Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine,Univ Gothenburg, Sweden,Sahlgrenska Academy
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- Daka, Bledar, 1976 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine,Univ Gothenburg, Sweden,Sahlgrenska Academy
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(creator_code:org_t)
- Springer Nature, 2023
- 2023
- English.
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In: Journal of human hypertension. - : Springer Nature. - 1476-5527 .- 0950-9240. ; 38, s. 140-5
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Abstract
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- It is still debated whether arterial elasticity provides prognostic information for cardiovascular risk beyond blood pressure measurements in a healthy population. To investigate the association between arterial elasticity obtained by radial artery pulse wave analysis and risk for cardiovascular diseases (CVD) in men and women. In 2002-2005, 2362 individuals (men=1186, 50.2%) not taking antihypertensive medication were included. C2 (small artery elasticity) was measured using the HDI/Pulse Wave CR2000. Data on acute myocardial infarction or stroke, fatal or non-fatal, was obtained between 2002-2019. Cox- regression was used to investigate associations between C2 and future CVD, adjusting for confounding factors such as age, sex, systolic blood pressure, heart rate, HOMA-IR (Homeostatic Model Assessment for Insulin Resistance), LDL- cholesterol, CRP (C-Reactive Protein), alcohol consumption, smoking and physical activity. At baseline, the mean age of 46±10.6 years and over the follow-up period, we observed 108 events 70 events in men [event rate: 5.9%], 38 in women [event rate: 3.2%]. In the fully adjusted model, and for each quartile decrease in C2, there was a significant increase in the risk for incident CVD by 36%. (HR=1.36, 95% CI: 1.01-1.82, p=0.041). The results were accentuated for all men (HR=1.74, 95% CI: 1.21-2.50, p=0.003) and women over the age of 50 years (HR=1.70, 95% CI: 0.69-4.20). We showed a strong and independent association between C2 and CVD in men. In women after menopause, similar tendencies and effect sizes were observed.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Allmänmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- General Practice (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Szaló, Gábor, 19 ...
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Hellgren, Margar ...
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Allison, Matthew
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Li, Ying
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Råstam, Lennart
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Rådholm, Karin
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show more...
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Bollano, Entela, ...
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Duprez, Daniel A
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Jacobs, David R
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Lindblad, Ulf, 1 ...
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Daka, Bledar, 19 ...
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and General Practice
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Cardiac and Card ...
- Articles in the publication
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Journal of human ...
- By the university
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University of Gothenburg
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Linköping University
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Lund University