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Psychosocial factor...
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Rosengren, Annika,1951
(författare)
Psychosocial factors and venous thromboembolism: a long-term follow-up study of Swedish men
- Artikel/kapitelEngelska2008
Förlag, utgivningsår, omfång ...
Nummerbeteckningar
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LIBRIS-ID:oai:gup.ub.gu.se/72347
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https://gup.ub.gu.se/publication/72347URI
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https://doi.org/10.1111/j.1538-7836.2007.02857.xDOI
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Klassifikation
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
Anmärkningar
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BACKGROUND: The link between psychosocial factors and coronary heart disease is well established, but although effects on coagulation and fibrinolysis variables may be implicated, no population-based study has sought to determine whether venous thromboembolism is similarly related to psychosocial factors. OBJECTIVE: To determine whether venous thromboembolism (deep vein thrombosis or pulmonary embolism) is related to psychosocial factors. PATIENTS/METHODS: A stress questionnaire was filled in by 6958 men at baseline from 1970 to 1973, participants in a cardiovascular intervention trial. Their occupation was used to determine socio-economic status. RESULTS: After a maximum follow-up of 28.8 years, 358 cases of deep vein thrombosis and/or pulmonary embolism were identified through the Swedish hospital discharge and cause-specific death registries. In comparison with men who, at baseline, had no or moderate stress, men with persistent stress had increased risk of pulmonary embolism [hazard ratio (HR)=1.80, 95% CI: 1.21-2.67]. After multivariable adjustment, the HR decreased slightly to 1.66 (95% CI: 1.12-2.48). When compared with manual workers, men with white-collar jobs at intermediate or high level and professionals showed an inverse relationship between occupational class and pulmonary embolism (multiple-adjusted HR=0.57, 95% CI: 0.39-0.83). Deep vein thrombosis was not significantly related to either stress or occupational class. CONCLUSION: Both persistent stress and low occupational class were independently related to future pulmonary embolism. The mechanisms are unknown, but effects on coagulation and fibrinolytic factors are likely.
Ämnesord och genrebeteckningar
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MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Kardiologi hsv//swe
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MEDICAL AND HEALTH SCIENCES Clinical Medicine Cardiac and Cardiovascular Systems hsv//eng
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Aged
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80 and over
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Alcoholism/epidemiology
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Body Mass Index
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Cardiovascular Diseases/mortality
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Confounding Factors (Epidemiology)
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Diabetes Mellitus/epidemiology
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Follow-Up Studies
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Humans
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Hyperlipidemias/epidemiology
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Hypertension/epidemiology
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Intervention Studies
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Leisure Activities
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Male
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Neoplasms/mortality
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Occupations/statistics & numerical data
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Proportional Hazards Models
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Pulmonary Embolism/*epidemiology/etiology/psychology
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Questionnaires
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Risk Factors
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Smoking/epidemiology
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Social Class
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Stress
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Psychological/*epidemiology
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Sweden/epidemiology
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Thrombophlebitis/*epidemiology/etiology/psychology
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Freden, M.
(författare)
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Hansson, Per-Olof,1958
(författare)
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Wilhelmsen, Lars,1932Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för akut och kardiovaskulär medicin,Institute of Medicine, Department of Emergeny and Cardiovascular Medicine(Swepub:gu)xwilhl
(författare)
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Wedel, H.
(författare)
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Eriksson, Henry,1946
(författare)
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Göteborgs universitetInstitutionen för medicin, avdelningen för akut och kardiovaskulär medicin
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Journal of Thrombosis and Haemostasis: Elsevier BV6:4, s. 558-641538-7836
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