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Sökning: onr:"swepub:oai:lup.lub.lu.se:04e51085-6ebc-4e82-9279-ab6ed59c12e7" > Glucocorticoid use ...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00006848naa a2200877 4500
001oai:lup.lub.lu.se:04e51085-6ebc-4e82-9279-ab6ed59c12e7
003SwePub
008180420s2018 | |||||||||||000 ||eng|
009oai:prod.swepub.kib.ki.se:137952894
0247 a https://lup.lub.lu.se/record/04e51085-6ebc-4e82-9279-ab6ed59c12e72 URI
0247 a https://doi.org/10.1093/rheumatology/kex4442 DOI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1379528942 URI
040 a (SwePub)lud (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
1001 a Little, Jayneu Christie NHS Foundation Trust,University of Manchester4 aut
2451 0a Glucocorticoid use and factors associated with variability in this use in the Systemic Lupus International Collaborating Clinics Inception Cohort
264 c 2018-01-18
264 1b Oxford University Press (OUP),c 2018
300 a 11 s.
520 a Objectives. To describe glucocorticoid (GC) use in the SLICC inception cohort and to explore factors associated with GC use. In particular we aimed to assess temporal trends in GC use and to what extent physician-related factors may influence use. Methods. Patients were recruited within 15 months of diagnosis of SLE from 33 centres between 1999 and 2011 and continue to be reviewed annually. Descriptive statistics were used to detail oral and parenteral GC use. Cross sectional and longitudinal analyses were performed to explore factors associated with GC use at enrolment and over time. Results. We studied 1700 patients with a mean (S.D.) follow-up duration of 7.26 (3.82) years. Over the entire study period, 1365 (81.3%) patients received oral GCs and 447 (26.3%) received parenteral GCs at some point. GC use was strongly associated with treatment centre, age, race/ethnicity, sex, disease duration and disease activity. There was no change in the proportion of patients on GCs or the average doses of GC used over time according to year of diagnosis. Conclusion. GCs remain a cornerstone in SLE management and there have been no significant changes in their use over the past 10-15 years. While patient and disease factors contribute to the variation in GC use, between-centre differences suggest that physician-related factors also contribute. Evidence-based treatment algorithms are needed to inform a more standardized approach to GC use in SLE.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Reumatologi och inflammation0 (SwePub)302102 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Rheumatology and Autoimmunity0 (SwePub)302102 hsv//eng
653 a Epidemiology
653 a Glucocorticoids
653 a Systemic lupus erythematosus
7001 a Parker, Benu Christie NHS Foundation Trust4 aut
7001 a Lunt, Marku University of Manchester4 aut
7001 a Hanly, John G.u Dalhousie University4 aut
7001 a Urowitz, Murray B.u University of Toronto4 aut
7001 a Clarke, Ann E.u University of Calgary4 aut
7001 a Romero-Diaz, Juanitau Instituto Nacional de Ciencias Médicas y Nutrición4 aut
7001 a Gordon, Carolineu University of Birmingham,City Hospital, Birmingham4 aut
7001 a Bae, Sang Cheolu Hanyang University4 aut
7001 a Bernatsky, Sashau McGill University Health Center4 aut
7001 a Wallace, Daniel J.u University of California, Los Angeles4 aut
7001 a Merrill, Joan T.u Oklahoma Medical Research Foundation4 aut
7001 a Buyon, Jillu New York University4 aut
7001 a Isenberg, David A.u University College London,NYU Hospital for Joint Diseases4 aut
7001 a Rahman, Anisuru University College London4 aut
7001 a Ginzler, Ellen M.u SUNY Downstate Health Sciences University,Feinstein Institute for Medical Research4 aut
7001 a Petri, Michelleu Johns Hopkins University School of Medicine4 aut
7001 a Dooley, Mary Anneu University of North Carolina4 aut
7001 a Fortin, Paulu Centre hospitalier universitaire de Québec4 aut
7001 a Gladman, Dafna D.u University of Toronto4 aut
7001 a Steinsson, Kristjanu National University Hospital of Iceland4 aut
7001 a Ramsey-Goldman, Rosalindu Northwestern University Feinberg School of Medicine4 aut
7001 a Khamashta, Munther A.u King's College London4 aut
7001 a Aranow, Cynthiau Feinstein Institute for Medical Research4 aut
7001 a Mackay, Megganu Feinstein Institute for Medical Research4 aut
7001 a Alarcón, Graciela S.u University of Alabama4 aut
7001 a Manzi, Susanu Allegheny Health Network4 aut
7001 a Nived, Olau Lund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)reum-oni
7001 a Jönsen, Andreasu Lund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)reum-ajo
7001 a Zoma, Asad A.u Hairmyres Hospital4 aut
7001 a van Vollenhoven, Ronald F.u Karolinska Institutet,Karolinska Institute4 aut
7001 a Ramos-Casals, Manuelu Hospital Clínic of Barcelona4 aut
7001 a Ruiz-Irastorza, Guillermou University of the Basque Country4 aut
7001 a Lim, Sung Samu Emory University4 aut
7001 a Kalunian, Kenneth C.u University of California, San Diego4 aut
7001 a Inanc, Muratu Istanbul University4 aut
7001 a Kamen, Diane L.u Medical University of South Carolina4 aut
7001 a Peschken, Christine A.u University of Manitoba4 aut
7001 a Jacobsen, Sorenu Copenhagen University Hospital4 aut
7001 a Askanase, Ancau NYU Hospital for Joint Diseases4 aut
7001 a Sanchez-Guerrero, Jorgeu University of Toronto4 aut
7001 a Bruce, Ian N.u University of Manchester,Christie NHS Foundation Trust4 aut
7102 a Christie NHS Foundation Trustb University of Manchester4 org
7730 t Rheumatology (United Kingdom)d : Oxford University Press (OUP)g 57:4, s. 677-687q 57:4<677-687x 1462-0324x 1462-0332
8564 u http://dx.doi.org/10.1093/rheumatology/kex444y FULLTEXT
8564 u https://academic.oup.com/rheumatology/article-pdf/57/4/677/25092262/kex444.pdf
8564 8u https://lup.lub.lu.se/record/04e51085-6ebc-4e82-9279-ab6ed59c12e7
8564 8u https://doi.org/10.1093/rheumatology/kex444
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:137952894

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