Sökning: onr:"swepub:oai:lup.lub.lu.se:1b6c1b53-7c3e-4e1e-bfa5-da409ba6e3eb" > Brain energy metabo...
Fältnamn | Indikatorer | Metadata |
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000 | 04488naa a2200625 4500 | |
001 | oai:lup.lub.lu.se:1b6c1b53-7c3e-4e1e-bfa5-da409ba6e3eb | |
003 | SwePub | |
008 | 240208| | |||||||||||000 ||eng| | |
024 | 7 | a https://lup.lub.lu.se/record/1b6c1b53-7c3e-4e1e-bfa5-da409ba6e3eb2 URI |
024 | 7 | a https://doi.org/10.1111/jnc.160322 DOI |
040 | a (SwePub)lu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a art2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a Rae, Caroline D.u University of New South Wales4 aut |
245 | 1 0 | a Brain energy metabolism : A roadmap for future research |
520 | a Although we have learned much about how the brain fuels its functions over the last decades, there remains much still to discover in an organ that is so complex. This article lays out major gaps in our knowledge of interrelationships between brain metabolism and brain function, including biochemical, cellular, and subcellular aspects of functional metabolism and its imaging in adult brain, as well as during development, aging, and disease. The focus is on unknowns in metabolism of major brain substrates and associated transporters, the roles of insulin and of lipid droplets, the emerging role of metabolism in microglia, mysteries about the major brain cofactor and signaling molecule NAD+, as well as unsolved problems underlying brain metabolism in pathologies such as traumatic brain injury, epilepsy, and metabolic downregulation during hibernation. It describes our current level of understanding of these facets of brain energy metabolism as well as a roadmap for future research. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Neurovetenskaper0 (SwePub)301052 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Neurosciences0 (SwePub)301052 hsv//eng |
653 | a acetate | |
653 | a aerobic glycolysis | |
653 | a GLUT4 | |
653 | a insulin | |
653 | a noradrenaline | |
700 | 1 | a Baur, Joseph A.u University of Pennsylvania4 aut |
700 | 1 | a Borges, Karinu University of Queensland4 aut |
700 | 1 | a Dienel, Geraldu University of New Mexico School of Medicine4 aut |
700 | 1 | a Díaz-García, Carlos Manlio4 aut |
700 | 1 | a Douglass, Starlette R.u University at Albany, SUNY4 aut |
700 | 1 | a Drew, Kellyu University of Alaska Fairbanks4 aut |
700 | 1 | a Duarte, João M Nu Lund University,Lunds universitet,Diabetes och hjärnans funktion,Forskargrupper vid Lunds universitet,WCMM- Wallenberg center för molekylär medicinsk forskning,Medicinska fakulteten,LU profilområde: Proaktivt åldrande,Lunds universitets profilområden,Diabetes and Brain Function,Lund University Research Groups,WCMM-Wallenberg Centre for Molecular Medicine,Faculty of Medicine,LU Profile Area: Proactive Ageing,Lund University Profile areas4 aut0 (Swepub:lu)jo2654du |
700 | 1 | a Duran, Jordiu Ramon Llull University,Institute for Bioengineering of Catalonia (IBEC)4 aut |
700 | 1 | a Kann, Oliveru Heidelberg University4 aut |
700 | 1 | a Kristian, Tiboru University of Maryland School of Medicine4 aut |
700 | 1 | a Lee-Liu, Dasfne4 aut |
700 | 1 | a Lindquist, Britta E.u University of California, San Francisco4 aut |
700 | 1 | a McNay, Ewan C.u University at Albany, SUNY4 aut |
700 | 1 | a Robinson, Michael B.u The Children's Hospital of Philadelphia4 aut |
700 | 1 | a Rothman, Douglas L.u Yale University4 aut |
700 | 1 | a Rowlands, Benjamin D.u University of Sydney4 aut |
700 | 1 | a Ryan, Timothy A.u Weill Cornell Medical College4 aut |
700 | 1 | a Scafidi, Josephu Johns Hopkins University School of Medicine4 aut |
700 | 1 | a Scafidi, Susannau Johns Hopkins University School of Medicine4 aut |
700 | 1 | a Shuttleworth, C. Williamu University of New Mexico School of Medicine4 aut |
700 | 1 | a Swanson, Raymond A.u University of California, San Francisco4 aut |
700 | 1 | a Uruk, Gökhanu University of California, San Francisco4 aut |
700 | 1 | a Vardjan, Nina4 aut |
700 | 1 | a Zorec, Robert4 aut |
700 | 1 | a McKenna, Mary C.u University of Maryland School of Medicine4 aut |
710 | 2 | a University of New South Walesb University of Pennsylvania4 org |
773 | 0 | t Journal of Neurochemistryx 0022-3042 |
856 | 4 | u http://dx.doi.org/10.1111/jnc.16032x freey FULLTEXT |
856 | 4 8 | u https://lup.lub.lu.se/record/1b6c1b53-7c3e-4e1e-bfa5-da409ba6e3eb |
856 | 4 8 | u https://doi.org/10.1111/jnc.16032 |
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