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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00009512naa a2200685 4500
001oai:lup.lub.lu.se:241f0297-6889-4d09-bc6d-05ec8368af9c
003SwePub
008201104s2020 | |||||||||||000 ||eng|
009oai:gup.ub.gu.se/296977
024a https://lup.lub.lu.se/record/241f0297-6889-4d09-bc6d-05ec8368af9c2 URI
024a https://doi.org/10.1186/s12872-020-01721-92 DOI
024a https://gup.ub.gu.se/publication/2969772 URI
040 a (SwePub)lud (SwePub)gu
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
100a Blennow Nordström, Eriku Lund University,Lunds universitet,Neurologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Centrum för hjärtstopp,Forskargrupper vid Lunds universitet,Brain Injury After Cardiac Arrest,Neurology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Center for cardiac arrest,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)er0251bl
2451 0a Neuropsychological outcome after cardiac arrest : A prospective case control sub-study of the Targeted hypothermia versus targeted normothermia after out-of-hospital cardiac arrest trial (TTM2)
264 c 2020-10-07
264 1b Springer Science and Business Media LLC,c 2020
520 a Background: This study is designed to provide detailed knowledge on cognitive impairment after out-of-hospital cardiac arrest (OHCA) and its relation to associated factors, and to validate the neurocognitive screening of the Targeted Hypothermia versus Targeted Normothermia after Out-of-Hospital Cardiac Arrest trial (TTM2-trial), assessing effectiveness of targeted temperature management after OHCA. Methods: This longitudinal multi-center clinical study is a sub-study of the TTM2-trial, in which a comprehensive neuropsychological examination is performed in addition to the main TTM2-trial neurocognitive screening. Approximately 7 and 24 months after OHCA, survivors at selected study sites are invited to a standardized assessment, including performance-based tests of cognition and questionnaires of emotional problems, fatigue, executive function and insomnia. At 1:1 ratio, a matched control group from a cohort of acute myocardial infarction (MI) patients is recruited to perform the same assessment. We aim to include 100 patients per group. Potential differences between the OHCA patients and the MI controls at 7 and 24 months will be analyzed with a linear regression, using composite z-scores per cognitive domain (verbal, visual/constructive, working memory, episodic memory, processing speed, executive functions) as primary outcome measures. Results from OHCA survivors on the main TTM2-trial neurocognitive screening battery will be compared with neuropsychological test results at 7 months, using sensitivity and specificity analyses. Discussion: In this study we collect detailed information on cognitive impairment after OHCA and compare this to a control group of patients with acute MI. The validation of the TTM2 neurocognitive screening battery could justify its inclusion in routine follow-up. Our results may have a potential to impact on the design of future follow-up strategies and interventions after OHCA. Trial registration: ClinicalTrials.gov, NCT03543371. Registered 1 June 2018
650 7a SAMHÄLLSVETENSKAPx Psykologix Tillämpad psykologi0 (SwePub)501022 hsv//swe
650 7a SOCIAL SCIENCESx Psychologyx Applied Psychology0 (SwePub)501022 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Neurologi0 (SwePub)302072 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Neurology0 (SwePub)302072 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Anestesi och intensivvård0 (SwePub)302012 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Anesthesiology and Intensive Care0 (SwePub)302012 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng
653 a Cardiac arrest
653 a Cognitive dysfunction
653 a Cognitive screening
653 a Neuropsychological tests
653 a Outcome
700a Lilja, Giselau Lund University,Lunds universitet,Neurologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Centrum för hjärtstopp,Forskargrupper vid Lunds universitet,Brain Injury After Cardiac Arrest,Neurology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Center for cardiac arrest,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)med-gal
700a Vestberg, Susannau Lund University,Lunds universitet,Psykiatri, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Institutionen för psykologi,Samhällsvetenskapliga institutioner och centrumbildningar,Samhällsvetenskapliga fakulteten,Psychiatry (Lund),Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Department of Psychology,Departments of Administrative, Economic and Social Sciences,Faculty of Social Sciences4 aut0 (Swepub:lu)psyk-vsu
700a Ullén, Susannu Skåne University Hospital4 aut0 (Swepub:lu)su7040ul
700a Friberg, Hansu Lund University,Lunds universitet,Anestesiologi och intensivvård,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Centrum för hjärtstopp,Forskargrupper vid Lunds universitet,SWECRIT,Anesthesiology and Intensive Care,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Center for cardiac arrest,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)efor-hfr
700a Nielsen, Niklasu Lund University,Lunds universitet,Anestesiologi och intensivvård,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Kliniska Vetenskaper, Helsingborg,Institutionen för kliniska vetenskaper, Lund,Centrum för hjärtstopp,Forskargrupper vid Lunds universitet,SEBRA Sepsis and Bacterial Resistance Alliance,Anesthesiology and Intensive Care,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Clinical Sciences, Helsingborg,Department of Clinical Sciences, Lund,Center for cardiac arrest,Lund University Research Groups,Helsingborg Hospital4 aut0 (Swepub:lu)med-nni
700a Heimburg, Katarinau Lund University,Lunds universitet,Neurologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Brain Injury After Cardiac Arrest,Forskargrupper vid Lunds universitet,Neurology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)ka7876he
700a Evald, Larsu Regionshospitalet Hammel Neurocenter4 aut
700a Mion, Marcou Basildon and Thurrock University Hospitals4 aut
700a Segerström, Magnusu Sahlgrenska University Hospital4 aut
700a Grejs, Anders M.u Aarhus University Hospital4 aut
700a Keeble, Thomasu Basildon and Thurrock University Hospitals4 aut
700a Kirkegaard, Hansu Aarhus University Hospital4 aut
700a Ljung, Hannau Lund University,Lunds universitet,Kliniska Vetenskaper, Helsingborg,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Epilepsicentrum,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Clinical Sciences, Helsingborg,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Epilepsy Center,Section IV,Department of Clinical Sciences, Lund,Skåne University Hospital4 aut0 (Swepub:lu)med-hlj
700a Rose, Sofiau Cardiff and Vale University Health Board4 aut
700a Wise, Matthew P.u Cardiff University4 aut
700a Rylander, Christian,d 1960u Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för anestesiologi och intensivvård,Institute of Clinical Sciences, Department of Anesthesiology and Intensive care4 aut0 (Swepub:gu)xrylch
700a Undén, Johanu Lund University,Lunds universitet,Anestesiologi och intensivvård,Forskargrupper vid Lunds universitet,Anaesthesiology and Intensive Care Medicine,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)neur-jun
700a Cronberg, Tobiasu Lund University,Lunds universitet,Neurologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Centrum för hjärtstopp,Forskargrupper vid Lunds universitet,Brain Injury After Cardiac Arrest,Neurology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Center for cardiac arrest,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)efor-tcr
710a Neurologi, Lundb Sektion IV4 org
773t BMC Cardiovascular Disordersd : Springer Science and Business Media LLCg 20:1q 20:1x 1471-2261
856u http://dx.doi.org/10.1186/s12872-020-01721-9x freey FULLTEXT
856u https://bmccardiovascdisord.biomedcentral.com/track/pdf/10.1186/s12872-020-01721-9
8564 8u https://lup.lub.lu.se/record/241f0297-6889-4d09-bc6d-05ec8368af9c
8564 8u https://doi.org/10.1186/s12872-020-01721-9
8564 8u https://gup.ub.gu.se/publication/296977

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