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- Andersen, PatriciaAalborg University Hospital (författare)
The impact of peripheral artery disease on major adverse cardiovascular events following myocardial infarction
- Artikel/kapitelEngelska2021
Förlag, utgivningsår, omfång ...
- Elsevier BV,2021
Nummerbeteckningar
- LIBRIS-ID:oai:lup.lub.lu.se:42b9776e-977d-479e-ac4f-a493c519f30a
- https://lup.lub.lu.se/record/42b9776e-977d-479e-ac4f-a493c519f30aURI
- https://doi.org/10.1016/j.ijcard.2021.08.053DOI
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- Språk:engelska
- Sammanfattning på:engelska
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- Aims: Peripheral artery disease (PAD) constitute a high-risk with adverse clinical outcomes. We aimed to investigate the cardiovascular outcomes following myocardial infarction (MI). Methods and results: This nationwide, Danish register-based follow-up study includes all patients experiencing an MI between 2000 and 2017. Patients with and without PAD were compared. Multivariable logistic regression was used to derive relative risks of 1-year major adverse cardiovascular events (MACE; all-cause mortality, reinfarction, stroke or heart failure). Individual components, cardiovascular mortality, and bleeding, standardized to age, sex and comorbidity distributions of all patients were assessed. MI patients with PAD (n = 5083, 2.9%) were older and more comorbid compared to patients without PAD (n = 174,673). After standardization, PAD was associated with higher 1-year relative risks of MACE (RR 1.21 [95% CI 1.17;1.25]), all-cause (RR 1.29 [95% CI 1.24;1.35]) and cardiovascular mortality (RR 1.3 [95% CI 1.24;1.36]), reinfarction (RR 1.17 [95% CI 1.11;1.22]), stroke (RR 1.12 [95% CI 0.92;1.32]), heart failure (RR 1.22 [95% CI 1.12;1.32]), and bleeding episodes (RR 1.25 [95% CI 1.04,1.46]). Similar results were seen in 30-day survivors after adjustment for antithrombotic post-discharge medication for MACE (RR 1.25 [95% CI 1.20,1.31]), all-cause mortality (RR 1.47 [95% CI 1.37,1.57], cardiovascular mortality (RR 1.49 [95% CI 1.37,1.61]), reinfarction (RR 1.17 [95% CI 1.08,1.12]) and heart failure (RR 1.22 [95% CI 1.12,1.32]). Conclusion: Comparing to patients without PAD, patients with PAD had increased 1-year relative risk of MACE, all-cause mortality, reinfarction, stroke, heart failure, cardiovascular mortality and bleeding following MI. The low prevalence of PAD is suggestive of considerable under-diagnosing.
Ämnesord och genrebeteckningar
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Kardiologi hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine Cardiac and Cardiovascular Systems hsv//eng
- Major adverse cardiovascular events
- Myocardial infarction
- Peripheral artery disease
Biuppslag (personer, institutioner, konferenser, titlar ...)
- Kragholm, KristianAalborg University Hospital (författare)
- Torp-Pedersen, ChristianAalborg University Hospital,Hillerod Hospital (författare)
- Jensen, Svend EggertAalborg University,Aalborg University Hospital (författare)
- Attar, RubinaLund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital,Aalborg University Hospital(Swepub:lu)ru0472at (författare)
- Aalborg University HospitalHillerod Hospital (creator_code:org_t)
Sammanhörande titlar
- Ingår i:International Journal of Cardiology: Elsevier BV345, s. 131-1370167-5273
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- International Journal of Cardiology (Sök värdpublikationen i LIBRIS)
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