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Measurable residual...
Measurable residual disease testing for personalized treatment of acute myeloid leukemia
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- Ehinger, Mats (författare)
- Lund University,Lunds universitet,Tumörmikromiljö,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Tumor microenvironment,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital
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- Pettersson, Louise (författare)
- Lund University,Lunds universitet,Tumörmikromiljö,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Tumor microenvironment,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine,Halmstad County Hospital
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(creator_code:org_t)
- 2019-03-28
- 2019
- Engelska.
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Ingår i: APMIS. - : Wiley. - 0903-4641 .- 1600-0463. ; 127:5, s. 337-351
- Relaterad länk:
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Abstract
Ämnesord
Stäng
- This review summarizes – with the practicing hematologist in mind – the methods used to determine measurable residual disease (MRD) in everyday practice with some future perspectives, and the current knowledge about the prognostic impact of MRD on outcome in acute myeloid leukemia (AML), excluding acute promyelocytic leukemia. Possible implications for choice of MRD method, timing of MRD monitoring, and guidance of therapy are discussed in general and in some detail for certain types of leukemia with specific molecular markers to monitor, including core binding factor (CBF)-leukemias and NPM1-mutated leukemias.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Hematologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Hematology (hsv//eng)
Nyckelord
- Acute myeloid leukemia
- CBF leukemia
- CBFB-MYH11
- flow cytometry
- inv(16)
- measurable residual disease
- multicolor flow cytometry
- NPM1
- personalized treatment
- RUNX1-RUNX1T1
- t(16;16)
- t(8;21)
Publikations- och innehållstyp
- for (ämneskategori)
- ref (ämneskategori)
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