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- Forslund, OlaLund University,Lunds universitet,Avdelningen för medicinsk mikrobiologi,Institutionen för laboratoriemedicin,Medicinska fakulteten,Division of Medical Microbiology,Department of Laboratory Medicine,Faculty of Medicine (author)
Mycoplasma genitalium and macrolide resistance-associated mutations in the Skåne Region of Southern Sweden 2015
- Article/chapterEnglish2017
Publisher, publication year, extent ...
- Medical Journals Sweden AB,2017
- 4 s.
Numbers
- LIBRIS-ID:oai:lup.lub.lu.se:852345de-f457-4bda-ac26-5a24cb41af04
- https://lup.lub.lu.se/record/852345de-f457-4bda-ac26-5a24cb41af04URI
- https://doi.org/10.2340/00015555-2746DOI
Supplementary language notes
- Language:English
- Summary in:English
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Notes
- Mycoplasma genitalium is a sexually transmitted infection ordinarily treated with azithromycin. Emerging resistance to macrolide is linked to mutations in the 23S rRNA gene. We analysed the frequency of such mutations of M. genitalium isolates from patients that were symptomatic, and from sexual partners of symptomatic individuals, from October to December of 2015, in the Skåne Region of Sweden. Mutations were analysed by the use of DNA sequencing. Overall, 11.9% (145/1,311) and 17.0% (116/704) of females and males were positive for M. genitalium, respectively. Macrolide resistant mutations were detected in 13% (31/239) of M. genitalium isolates from first-test patient samples. Twenty-one (8.8%) and 10 (4.2%) of the isolates had point mutations of the 23S-gene at position 2072 and 2071, respectively. Two different M. genitalium isolates were detected simultaneously in two cases. In summary, we found a relatively low rate of macrolide-resistant M. genitalium in the region of Southern Sweden.
Subject headings and genre
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Dermatologi och venereologi hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine Dermatology and Venereal Diseases hsv//eng
- Azithromycin
- Macrolide
- Mycoplasma genitalium
- Resistance
Added entries (persons, corporate bodies, meetings, titles ...)
- Hjelm, MaxLund University (author)
- El-Ali, RaghdLund University (author)
- Johnsson, AnnikaSkåne University Hospital(Swepub:lu)derm-ajo (author)
- Bjartling, CarinaSkåne University Hospital(Swepub:lu)obst-cbj (author)
- Avdelningen för medicinsk mikrobiologiInstitutionen för laboratoriemedicin (creator_code:org_t)
Related titles
- In:Acta Dermato-Venereologica: Medical Journals Sweden AB97:10, s. 1235-12380001-5555
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