Sökning: onr:"swepub:oai:lup.lub.lu.se:9737163f-4baf-4db0-9ed7-507f53fe30bf" > Lymphomyeloid Contr...
Fältnamn | Indikatorer | Metadata |
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000 | 06510naa a2200685 4500 | |
001 | oai:lup.lub.lu.se:9737163f-4baf-4db0-9ed7-507f53fe30bf | |
003 | SwePub | |
008 | 160401s2013 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:128061315 | |
024 | 7 | a https://lup.lub.lu.se/record/40655472 URI |
024 | 7 | a https://doi.org/10.1016/j.stem.2013.08.0122 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1280613152 URI |
040 | a (SwePub)lud (SwePub)ki | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a art2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a Böiers, Charlottau Lund University,Lunds universitet,Avdelningen för molekylärmedicin och genterapi,Institutionen för laboratoriemedicin,Medicinska fakulteten,Stamcellscentrum (SCC),Avdelningen för stamcellsforskning,Utvecklingslymfopoes och leukemi,Forskargrupper vid Lunds universitet,Division of Molecular Medicine and Gene Therapy,Department of Laboratory Medicine,Faculty of Medicine,Stem Cell Center,Division of stem cell research,Developmental lymphopoiesis and leukemia,Lund University Research Groups4 aut0 (Swepub:lu)mig-cbo |
245 | 1 0 | a Lymphomyeloid Contribution of an Immune-Restricted Progenitor Emerging Prior to Definitive Hematopoietic Stem Cells. |
264 | 1 | b Elsevier BV,c 2013 |
520 | a In jawed vertebrates, development of an adaptive immune-system is essential for protection of the born organism against otherwise life-threatening pathogens. Myeloid cells of the innate immune system are formed early in development, whereas lymphopoiesis has been suggested to initiate much later, following emergence of definitive hematopoietic stem cells (HSCs). Herein, we demonstrate that the embryonic lymphoid commitment process initiates earlier than previously appreciated, prior to emergence of definitive HSCs, through establishment of a previously unrecognized entirely immune-restricted and lymphoid-primed progenitor. Notably, this immune-restricted progenitor appears to first emerge in the yolk sac and contributes physiologically to the establishment of lymphoid and some myeloid components of the immune-system, establishing the lymphomyeloid lineage restriction process as an early and physiologically important lineage-commitment step in mammalian hematopoiesis. | |
650 | 7 | a NATURVETENSKAPx Biologix Cellbiologi0 (SwePub)106042 hsv//swe |
650 | 7 | a NATURAL SCIENCESx Biological Sciencesx Cell Biology0 (SwePub)106042 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinsk bioteknologix Medicinsk bioteknologi0 (SwePub)304012 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Medical Biotechnologyx Medical Biotechnology0 (SwePub)304012 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Hematologi0 (SwePub)302022 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Hematology0 (SwePub)302022 hsv//eng |
700 | 1 | a Carrelha, Joana4 aut |
700 | 1 | a Lutteropp, Michael4 aut |
700 | 1 | a Luc, Sidinhu Lund University,Lunds universitet,Stamcellscentrum (SCC),Avdelningen för stamcellsforskning,Institutionen för laboratoriemedicin,Medicinska fakulteten,Stem Cell Center,Division of stem cell research,Department of Laboratory Medicine,Faculty of Medicine4 aut0 (Swepub:lu)med-sil |
700 | 1 | a Green, Joanna C A4 aut |
700 | 1 | a Azzoni, Emanuele4 aut |
700 | 1 | a Woll, Petter S4 aut |
700 | 1 | a Mead, Adam J4 aut |
700 | 1 | a Hultquist, Anneu Lund University,Lunds universitet,Stamcellscentrum (SCC),Avdelningen för stamcellsforskning,Institutionen för laboratoriemedicin,Medicinska fakulteten,Stem Cell Center,Division of stem cell research,Department of Laboratory Medicine,Faculty of Medicine4 aut0 (Swepub:lu)stem-ahu |
700 | 1 | a Swiers, Gemma4 aut |
700 | 1 | a Perdiguero, Elisa Gomez4 aut |
700 | 1 | a Macaulay, Iain C4 aut |
700 | 1 | a Melchiori, Luca4 aut |
700 | 1 | a Luis, Tiago C4 aut |
700 | 1 | a Kharazi, Shabnamu Lund University,Lunds universitet,Stamcellscentrum (SCC),Avdelningen för stamcellsforskning,Institutionen för laboratoriemedicin,Medicinska fakulteten,Stem Cell Center,Division of stem cell research,Department of Laboratory Medicine,Faculty of Medicine4 aut0 (Swepub:lu)med-ksh |
700 | 1 | a Bouriez-Jones, Tiphaine4 aut |
700 | 1 | a Deng, Qiaolinu Karolinska Institutet4 aut |
700 | 1 | a Pontén, Annicau Lund University,Lunds universitet,Stamcellscentrum (SCC),Avdelningen för stamcellsforskning,Institutionen för laboratoriemedicin,Medicinska fakulteten,Stem Cell Center,Division of stem cell research,Department of Laboratory Medicine,Faculty of Medicine4 aut0 (Swepub:lu)med-anp |
700 | 1 | a Atkinson, Deborah4 aut |
700 | 1 | a Jensen, Christinau Lund University,Lunds universitet,Stamcellscentrum (SCC),Avdelningen för stamcellsforskning,Institutionen för laboratoriemedicin,Medicinska fakulteten,Stem Cell Center,Division of stem cell research,Department of Laboratory Medicine,Faculty of Medicine4 aut0 (Swepub:lu)stem-cje |
700 | 1 | a Sitnicka Quinn, Ewau Lund University,Lunds universitet,Stamcellscentrum (SCC),Avdelningen för stamcellsforskning,Institutionen för laboratoriemedicin,Medicinska fakulteten,Stem Cell Center,Division of stem cell research,Department of Laboratory Medicine,Faculty of Medicine4 aut0 (Swepub:lu)molm-esi |
700 | 1 | a Geissmann, Frederic4 aut |
700 | 1 | a Godin, Isabelle4 aut |
700 | 1 | a Sandberg, Rickardu Karolinska Institutet4 aut |
700 | 1 | a de Bruijn, Marella F T R4 aut |
700 | 1 | a Jacobsen, Sten Eirik Wu Karolinska Institutet,Lund University,Lunds universitet,Stamcellscentrum (SCC),Avdelningen för stamcellsforskning,Institutionen för laboratoriemedicin,Medicinska fakulteten,Stem Cell Center,Division of stem cell research,Department of Laboratory Medicine,Faculty of Medicine4 aut0 (Swepub:lu)stem-sja |
710 | 2 | a Avdelningen för molekylärmedicin och genterapib Institutionen för laboratoriemedicin4 org |
773 | 0 | t Cell Stem Celld : Elsevier BVg 13:5, s. 535-548q 13:5<535-548x 1934-5909x 1875-9777 |
856 | 4 | u http://www.ncbi.nlm.nih.gov/pubmed/24054998?dopt=Abstracty FULLTEXT |
856 | 4 | u http://dx.doi.org/10.1016/j.stem.2013.08.012y FULLTEXT |
856 | 4 | u http://www.cell.com/article/S1934590913003755/pdf |
856 | 4 8 | u https://lup.lub.lu.se/record/4065547 |
856 | 4 8 | u https://doi.org/10.1016/j.stem.2013.08.012 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:128061315 |
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