Comparative histochemical distribution of nerve fibres storing noradrenaline and neuropeptide Y (NPY) in human ovary, fallopian tube, and uterus

• Nerves containing noradrenaline were studied by formaldehyde-induced fluorescence and neuropeptide Y (NPY) was visualised by immunohistochemistry in the human ovary, Fallopian tube and uterus. All structures were richly supplied with noradrenergic fibres closely associated with the vascular and non-vascular smooth musculature. NPY-containing nerve terminals were consistently fewer, particularly in the ovary. The best developed nerve supply was found in the tubal isthmus and uterine cervix. Vessels were usually innervated by plexuses of nerves, containing NPY as well as noradrenaline. The discrepancy between the number of the two types of histochemically distinguishable nerves suggests that, if noradrenaline and NPY are co-localised in one and the same nerve, this is not a constant phenomenon in the human female reproductive tract.

Keyword

Fallopian Tubes/innervation

Female

Fluorescent Antibody Technique

Humans

Nerve Fibers/metabolism

Nerve Tissue Proteins/metabolism

Neuropeptide Y

Norepinephrine/metabolism

Ovary/innervation

Tissue Distribution

Uterus/innervation

Publication and Content Type

art (subject category)

ref (subject category)