Sökning: onr:"swepub:oai:lup.lub.lu.se:b0be8c33-2889-486b-b87d-2d49844c4146" > International Socie...
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000 | 04893naa a2200517 4500 | |
001 | oai:lup.lub.lu.se:b0be8c33-2889-486b-b87d-2d49844c4146 | |
003 | SwePub | |
008 | 210408s2022 | |||||||||||000 ||eng| | |
024 | 7 | a https://lup.lub.lu.se/record/b0be8c33-2889-486b-b87d-2d49844c41462 URI |
024 | 7 | a https://doi.org/10.1016/j.euf.2021.03.0172 DOI |
040 | a (SwePub)lu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a for2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a van der Kwast, Theou Princess Margaret Hospital University of Toronto4 aut |
245 | 1 0 | a International Society of Urological Pathology Expert Opinion on Grading of Urothelial Carcinoma |
264 | 1 | b Elsevier BV,c 2022 |
520 | a Context: Grading is the mainstay for treatment decisions for patients with non–muscle-invasive bladder cancer (NMIBC). Objective: To determine the requirements for an optimal grading system for NMIBC via expert opinion. Evidence acquisition: A multidisciplinary working group established by the International Society of Urological Pathology reviewed available clinical, histopathological, and molecular evidence for an optimal grading system for bladder cancer. Evidence synthesis: Bladder cancer grading is a continuum and five different grading systems based on historical grounds could be envisaged. Splitting of the World Health Organization (WHO) 2004 low-grade class for NMIBC lacks diagnostic reproducibility and molecular-genetic support, while showing little difference in progression rate. Subdividing the clinically heterogeneous WHO 2004 high-grade class for NMIBC into intermediate and high risk categories using the WHO 1973 grading is supported by both clinical and molecular-genetic findings. Grading criteria for the WHO 1973 scheme were detailed on the basis of literature findings and expert opinion. Conclusions: Splitting of the WHO 2004 high-grade category into WHO 1973 grade 2 and 3 subsets is recommended. Provision of more detailed histological criteria for the WHO 1973 grading might facilitate the general acceptance of a hybrid four-tiered grading system or—as a preferred option—a more reproducible three-tiered system distinguishing low-, intermediate (high)-, and high-grade NMIBC. Patient summary: Improvement of the current systems for grading bladder cancer may result in better informed treatment decisions for patients with bladder cancer. A three-tiered grading system for non–muscle invasive bladder cancer derived by splitting the heterogeneous World Health Organization (WHO) 2004 high-grade category into WHO 1973 grade 2 and 3 subsets is recommended, as this may result in more informed treatment decisions. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Urologi och njurmedicin0 (SwePub)302142 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Urology and Nephrology0 (SwePub)302142 hsv//eng |
653 | a Bladder cancer | |
653 | a Expert opinion | |
653 | a Grading system | |
653 | a Non-muscle invasive bladder cancer | |
653 | a Pathology | |
653 | a WHO 1973 | |
653 | a WHO 2004 | |
700 | 1 | a Liedberg, Fredriku Lund University,Lunds universitet,Urologi - blåscancer, Malmö,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Urology - urothelial cancer, Malmö,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Skåne University Hospital4 aut0 (Swepub:lu)urok-fli |
700 | 1 | a Black, Peter C.u University of British Columbia4 aut |
700 | 1 | a Kamat, Ashishu University of Texas MD Anderson Cancer Center4 aut |
700 | 1 | a van Rhijn, Bas W.G.u Antoni Van Leeuwenhoek Hospital4 aut |
700 | 1 | a Algaba, Ferranu Autonomous University of Barcelona4 aut |
700 | 1 | a Berman, David M.u Queen's University at Kingston4 aut |
700 | 1 | a Hartmann, Arndtu Friedrich-Alexander University Erlangen-Nürnberg4 aut |
700 | 1 | a Lopez-Beltran, Antoniou University of Córdoba, Spain4 aut |
700 | 1 | a Samaratunga, Hemamaliu University of Queensland,Aquesta Uropathology4 aut |
700 | 1 | a Varma, Muraliu University Hospital of Wales4 aut |
700 | 1 | a Cheng, Liangu Indiana University4 aut |
710 | 2 | a Princess Margaret Hospital University of Torontob Urologi - blåscancer, Malmö4 org |
773 | 0 | t European Urology Focusd : Elsevier BVg 8:2, s. 438-446q 8:2<438-446x 2405-4569 |
856 | 4 | u http://dx.doi.org/10.1016/j.euf.2021.03.017y FULLTEXT |
856 | 4 8 | u https://lup.lub.lu.se/record/b0be8c33-2889-486b-b87d-2d49844c4146 |
856 | 4 8 | u https://doi.org/10.1016/j.euf.2021.03.017 |
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