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Intake of individua...
Intake of individual fatty acids and risk of prostate cancer in the European prospective investigation into cancer and nutrition
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- Perez-Cornago, Aurora (författare)
- University of Oxford
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- Huybrechts, Inge (författare)
- International Agency for Research on Cancer, World Health Organization
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- Appleby, Paul N. (författare)
- University of Oxford
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- Schmidt, Julie A. (författare)
- University of Oxford
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- Crowe, Francesca L. (författare)
- University of Birmingham
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- Overvad, Kim (författare)
- Aarhus University
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- Tjønneland, Anne (författare)
- Danish Cancer Society
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- Kühn, Tilman (författare)
- German Cancer Research Centre
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- Katzke, Verena (författare)
- German Cancer Research Centre
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- Trichopoulou, Antonia (författare)
- Hellenic Health Foundation, Athens
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- Karakatsani, Anna (författare)
- National and Kapodistrian University of Athens,Hellenic Health Foundation, Athens
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- Peppa, Eleni (författare)
- Hellenic Health Foundation, Athens
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- Grioni, Sara (författare)
- Istituto Nazionale dei Tumori
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- Palli, Domenico (författare)
- Institute for Cancer Research, Prevention and Clinical Network (ISPRO)
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- Sacerdote, Carlotta (författare)
- Citta' della Salute e della Scienza Hospital-University of Turin
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- Tumino, Rosario (författare)
- Civic and M.P Arezzo Hospital
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- Bueno-de-Mesquita, H. Bas (författare)
- University Medical Center Utrecht,National Institute for Public Health and the Environment (RIVM),Imperial College London,University of Malaya
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- Larrañaga, Nerea (författare)
- CIBER Epidemiology and Public Health (CIBERESP),Biodonostia Health Research Institute
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- Sánchez, Maria Jose (författare)
- University of Granada,CIBER Epidemiology and Public Health (CIBERESP)
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- Quirós, J. Ramón (författare)
- Public Health Directorate
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- Ardanaz, Eva (författare)
- CIBER Epidemiology and Public Health (CIBERESP),Health Research Institute of Navarra (IDISNA)
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- Chirlaque, María Dolores (författare)
- CIBER Epidemiology and Public Health (CIBERESP),Murcia Regional Health Council,University of Murcia
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- Agudo, Antonio (författare)
- L'Hospitalet de Llobregat, Barcelona,Catalan Institute of Oncology
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- Bjartell, Anders (författare)
- Lund University,Lunds universitet,Urologisk cancerforskning, Malmö,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Urological cancer, Malmö,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Skåne University Hospital
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- Wallström, Peter (författare)
- Lund University,Lunds universitet,Nutritionsepidemiologi,Forskargrupper vid Lunds universitet,Nutrition Epidemiology,Lund University Research Groups,Skåne University Hospital
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- Chajes, Veronique (författare)
- International Agency for Research on Cancer, World Health Organization
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- Tsilidis, Konstantinos K. (författare)
- University of Ioannina,Imperial College London
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- Aune, Dagfinn (författare)
- Bjørknes University College,Imperial College London,Oslo university hospital
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- Riboli, Elio (författare)
- Imperial College London
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- Travis, Ruth C. (författare)
- University of Oxford
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- Key, Timothy J. (författare)
- University of Oxford
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(creator_code:org_t)
- 2019-03-14
- 2020
- Engelska.
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Ingår i: International Journal of Cancer. - : Wiley. - 0020-7136 .- 1097-0215. ; 146:1, s. 44-57
- Relaterad länk:
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http://dx.doi.org/10... (free)
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https://onlinelibrar...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- The associations of individual dietary fatty acids with prostate cancer risk have not been examined comprehensively. We examined the prospective association of individual dietary fatty acids with prostate cancer risk overall, by tumor subtypes, and prostate cancer death. 142,239 men from the European Prospective Investigation into Cancer and Nutrition who were free from cancer at recruitment were included. Dietary intakes of individual fatty acids were estimated using center-specific validated dietary questionnaires at baseline and calibrated with 24-h recalls. Multivariable Cox regression models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs). After an average follow-up of 13.9 years, 7,036 prostate cancer cases and 936 prostate cancer deaths were ascertained. Intakes of individual fatty acids were not related to overall prostate cancer risk. There was evidence of heterogeneity in the association of some short chain saturated fatty acids with prostate cancer risk by tumor stage (p heterogeneity < 0.015), with a positive association with risk of advanced stage disease for butyric acid (4:0; HR 1SD = 1.08; 95%CI = 1.01–1.15; p-trend = 0.026). There were no associations with fatal prostate cancer, with the exception of a slightly higher risk for those who consumed more eicosenoic acid (22:1n-9c; HR 1SD = 1.05; 1.00–1.11; p-trend = 0.048) and eicosapentaenoic acid (20:5n-3c; HR 1SD = 1.07; 1.00–1.14; p-trend = 0.045). There was no evidence that dietary intakes of individual fatty acids were associated with overall prostate cancer risk. However, a higher intake of butyric acid might be associated with a higher risk of advanced, whereas intakes of eicosenoic and eicosapentaenoic acids might be positively associated with fatal prostate cancer risk.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Näringslära (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Nutrition and Dietetics (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Nyckelord
- individual fatty acids
- prospective
- prostate cancer
- tumor subtypes
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Perez-Cornago, A ...
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Huybrechts, Inge
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Appleby, Paul N.
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Schmidt, Julie A ...
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Crowe, Francesca ...
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Overvad, Kim
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visa fler...
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Tjønneland, Anne
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Kühn, Tilman
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Katzke, Verena
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Trichopoulou, An ...
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Karakatsani, Ann ...
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Peppa, Eleni
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Grioni, Sara
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Palli, Domenico
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Sacerdote, Carlo ...
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Tumino, Rosario
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Bueno-de-Mesquit ...
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Larrañaga, Nerea
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Sánchez, Maria J ...
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Quirós, J. Ramón
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Ardanaz, Eva
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Chirlaque, María ...
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Agudo, Antonio
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Bjartell, Anders
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Wallström, Peter
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Chajes, Veroniqu ...
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Tsilidis, Konsta ...
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Aune, Dagfinn
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Riboli, Elio
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Travis, Ruth C.
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Key, Timothy J.
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Hälsovetenskap
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och Folkhälsovetensk ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Hälsovetenskap
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och Näringslära
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Cancer och onkol ...
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Lunds universitet