Sökning: onr:"swepub:oai:lup.lub.lu.se:e94933e6-b01a-43de-a6f8-96018ba5c03b" > Fruit and vegetable...
Fältnamn | Indikatorer | Metadata |
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000 | 06534naa a2201021 4500 | |
001 | oai:lup.lub.lu.se:e94933e6-b01a-43de-a6f8-96018ba5c03b | |
003 | SwePub | |
008 | 160404s2010 | |||||||||||000 ||eng| | |
009 | oai:DiVA.org:umu-34540 | |
024 | 7 | a https://lup.lub.lu.se/record/15954832 URI |
024 | 7 | a https://doi.org/10.1093/jnci/djq0722 DOI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-345402 URI |
040 | a (SwePub)lud (SwePub)umu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a art2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a Boffetta, Paolo4 aut |
245 | 1 0 | a Fruit and vegetable intake and overall cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC). |
264 | c 2010-04-21 | |
264 | 1 | b Oxford University Press (OUP),c 2010 |
520 | a BACKGROUND: It is widely believed that cancer can be prevented by high intake of fruits and vegetables. However, inconsistent results from many studies have not been able to conclusively establish an inverse association between fruit and vegetable intake and overall cancer risk. METHODS: We conducted a prospective analysis of the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort to assess relationships between intake of total fruits, total vegetables, and total fruits and vegetables combined and cancer risk during 1992-2000. Detailed information on the dietary habit and lifestyle variables of the cohort was obtained. Cancer incidence and mortality data were ascertained, and hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated using multivariable Cox regression models. Analyses were also conducted for cancers associated with tobacco and alcohol after stratification for tobacco smoking and alcohol drinking. RESULTS: Of the initial 142 605 men and 335 873 women included in the study, 9604 men and 21 000 women were identified with cancer after a median follow-up of 8.7 years. The crude cancer incidence rates were 7.9 per 1000 person-years in men and 7.1 per 1000 person-years in women. Associations between reduced cancer risk and increased intake of total fruits and vegetables combined and total vegetables for the entire cohort were similar (200 g/d increased intake of fruits and vegetables combined, HR = 0.97, 95% CI = 0.96 to 0.99; 100 g/d increased intake of total vegetables, HR = 0.98, 95% CI = 0.97 to 0.99); intake of fruits showed a weaker inverse association (100 g/d increased intake of total fruits, HR = 0.99, 95% CI = 0.98 to 1.00). The reduced risk of cancer associated with high vegetable intake was restricted to women (HR = 0.98, 95% CI = 0.97 to 0.99). Stratification by alcohol intake suggested a stronger reduction in risk in heavy drinkers and was confined to cancers caused by smoking and alcohol. CONCLUSIONS: A very small inverse association between intake of total fruits and vegetables and cancer risk was observed in this study. Given the small magnitude of the observed associations, caution should be applied in their interpretation. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng |
653 | a Neoplasms: epidemiology | |
653 | a Alcohol Drinking: adverse effects | |
653 | a Europe: epidemiology | |
653 | a Neoplasms: prevention & control | |
653 | a Neoplasms: etiology | |
700 | 1 | a Couto, Elisabeth4 aut |
700 | 1 | a Wichmann, Janine4 aut |
700 | 1 | a Ferrari, Pietro4 aut |
700 | 1 | a Trichopoulos, Dimitrios4 aut |
700 | 1 | a Bueno-de-Mesquita, H Bas4 aut |
700 | 1 | a van Duijnhoven, Fränzel J B4 aut |
700 | 1 | a Büchner, Frederike L4 aut |
700 | 1 | a Key, Tim4 aut |
700 | 1 | a Boeing, Heiner4 aut |
700 | 1 | a Nöthlings, Ute4 aut |
700 | 1 | a Linseisen, Jakob4 aut |
700 | 1 | a Gonzalez, Carlos A4 aut |
700 | 1 | a Overvad, Kim4 aut |
700 | 1 | a Nielsen, Michael R S4 aut |
700 | 1 | a Tjønneland, Anne4 aut |
700 | 1 | a Olsen, Anja4 aut |
700 | 1 | a Clavel-Chapelon, Françoise4 aut |
700 | 1 | a Boutron-Ruault, Marie-Christine4 aut |
700 | 1 | a Morois, Sophie4 aut |
700 | 1 | a Lagiou, Pagona4 aut |
700 | 1 | a Naska, Androniki4 aut |
700 | 1 | a Benetou, Vassiliki4 aut |
700 | 1 | a Kaaks, Rudolf4 aut |
700 | 1 | a Rohrmann, Sabine4 aut |
700 | 1 | a Panico, Salvatore4 aut |
700 | 1 | a Sieri, Sabina4 aut |
700 | 1 | a Vineis, Paolo4 aut |
700 | 1 | a Palli, Domenico4 aut |
700 | 1 | a van Gils, Carla H4 aut |
700 | 1 | a Peeters, Petra H4 aut |
700 | 1 | a Lund, Eiliv4 aut |
700 | 1 | a Brustad, Magritt4 aut |
700 | 1 | a Engeset, Dagrun4 aut |
700 | 1 | a Huerta, José María4 aut |
700 | 1 | a Rodríguez, Laudina4 aut |
700 | 1 | a Sánchez, Maria-José4 aut |
700 | 1 | a Dorronsoro, Miren4 aut |
700 | 1 | a Barricarte, Aurelio4 aut |
700 | 1 | a Hallmans, Göran,d 1947-u Umeå universitet,Näringsforskning4 aut0 (Swepub:umu)goha0001 |
700 | 1 | a Johansson, Ingegerdu Umeå universitet,Näringsforskning,Kariologi4 aut0 (Swepub:umu)injo0003 |
700 | 1 | a Manjer, Jonasu Lund University,Lunds universitet,Kirurgi,Forskargrupper vid Lunds universitet,Surgery,Lund University Research Groups4 aut0 (Swepub:lu)smi-jma |
700 | 1 | a Sonestedt, Emilyu Lund University,Lunds universitet,Institutionen för kliniska vetenskaper, Malmö,Medicinska fakulteten,Department of Clinical Sciences, Malmö,Faculty of Medicine4 aut0 (Swepub:lu)medf-eso |
700 | 1 | a Allen, Naomi E4 aut |
700 | 1 | a Bingham, Sheila4 aut |
700 | 1 | a Khaw, Kay-Tee4 aut |
700 | 1 | a Slimani, Nadia4 aut |
700 | 1 | a Jenab, Mazda4 aut |
700 | 1 | a Mouw, Traci4 aut |
700 | 1 | a Norat, Teresa4 aut |
700 | 1 | a Riboli, Elio4 aut |
700 | 1 | a Trichopoulou, Antonia4 aut |
710 | 2 | a Umeå universitetb Näringsforskning4 org |
773 | 0 | t Journal of the National Cancer Instituted : Oxford University Press (OUP)g 102:8, s. 529-537q 102:8<529-537x 1460-2105x 0027-8874 |
856 | 4 | u http://www.ncbi.nlm.nih.gov/pubmed/20371762?dopt=Abstracty FULLTEXT |
856 | 4 | u http://dx.doi.org/10.1093/jnci/djq072y FULLTEXT |
856 | 4 | u https://academic.oup.com/jnci/article-pdf/102/8/529/17310951/djq072.pdf |
856 | 4 8 | u https://lup.lub.lu.se/record/1595483 |
856 | 4 8 | u https://doi.org/10.1093/jnci/djq072 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-34540 |
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