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Proteome
Proteome
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- Westergren-Thorsson, G. (author)
- Lund University,Lunds universitet,Lungbiologi,Forskargrupper vid Lunds universitet,WCMM- Wallenberg center för molekylär medicinsk forskning,Medicinska fakulteten,Lung Biology,Lund University Research Groups,WCMM-Wallenberg Centre for Molecular Medicine,Faculty of Medicine
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- Marko-Varga, G. (author)
- Lund University,Lunds universitet,Avdelningen för Biomedicinsk teknik,Institutionen för biomedicinsk teknik,Institutioner vid LTH,Lunds Tekniska Högskola,Clinical Protein Science and Imaging,Forskargrupper vid Lunds universitet,Department of Biomedical Engineering,Departments at LTH,Faculty of Engineering, LTH,Lund University Research Groups
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- Malmström, J. (author)
- University of Washington, Seattle
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- Larsen, K. (author)
- Lund University,Lunds universitet,Lungbiologi,Forskargrupper vid Lunds universitet,Lung Biology,Lund University Research Groups
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(creator_code:org_t)
- 2006
- 2006
- English.
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In: Encyclopedia of Respiratory Medicine : Volume 1-4 - Volume 1-4. - 9780123708793 - 9780123708793 ; 1-4, s. 527-532
- Related links:
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Abstract
Subject headings
Close
- Proteomics can be defined as the studies of protein properties on a large scale to obtain a global view of biological processes at the protein level. Essentially, proteomics requires protein separation and identification, and in many cases quantification. The cornerstones in proteomics are protein/peptide separation by gel electrophoresis and/or different chromatographic techniques, and identification by mass spectrometry followed by bioinformatic and biological interpretation of data. By combining these different separation techniques and mass spectrometry it is now possible to identify low abundant proteins with 10-1000 copies per cell. Today, substantial research efforts in proteome studies of the lung are focused on obtaining new diagnostic markers, as well as fingerprinting disease mechanisms.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)
Keyword
- Bioinformatics
- Broncheoalveolar lavage
- Fibroblasts
- Gel electrophoresis
- Gene ontology
- Lung
- Mass spectrometry
- Peptides
- Protein
- Proteome
Publication and Content Type
- kap (subject category)
- vet (subject category)
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