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Imaging in gynecolo...
Imaging in gynecological disease (23) : clinical and ultrasound characteristics of ovarian carcinosarcoma
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- Ciccarone, F. (författare)
- Policlinico Universitario Agostino Gemelli
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- Biscione, A. (författare)
- Policlinico Universitario Agostino Gemelli
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- Moro, F. (författare)
- Policlinico Universitario Agostino Gemelli
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visa fler...
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- Fischerova, D. (författare)
- Charles University in Prague
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Savelli, L. (författare)
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- Munaretto, M. (författare)
- St. Orsola-Malpighi University Hospital
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- Jokubkiene, L. (författare)
- Lund University,Lunds universitet,Urogynekologi och reproduktionsfarmakologi,Forskargrupper vid Lunds universitet,Urogynaecology and Reproductive Pharmacology,Lund University Research Groups,Skåne University Hospital
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- Sladkevicius, P. (författare)
- Lund University,Lunds universitet,Obstetrisk, gynekologisk och prenatal ultraljudsdiagnostik,Forskargrupper vid Lunds universitet,Obstetric, Gynaecological and Prenatal Ultrasound Research,Lund University Research Groups,Skåne University Hospital
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- Chiappa, V. (författare)
- Istituto Nazionale dei Tumori
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- Fruscio, R. (författare)
- University of Milano-Bicocca
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- Franchi, D. (författare)
- European Institute of Oncology
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- Epstein, E. (författare)
- Karolinska Institutet
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- Timmerman, D. (författare)
- University Hospitals Leuven,Catholic University of Leuven
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- Froyman, W. (författare)
- Catholic University of Leuven,University Hospitals Leuven
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- Valentin, L. (författare)
- Lund University,Lunds universitet,Obstetrisk, gynekologisk och prenatal ultraljudsdiagnostik,Forskargrupper vid Lunds universitet,Obstetric, Gynaecological and Prenatal Ultrasound Research,Lund University Research Groups,Skåne University Hospital
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- Scambia, G. (författare)
- Catholic University of the Sacred Heart, Rome,Policlinico Universitario Agostino Gemelli
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- Testa, A. C. (författare)
- Policlinico Universitario Agostino Gemelli,Catholic University of the Sacred Heart, Rome
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(creator_code:org_t)
- 2022-02
- 2022
- Engelska 7 s.
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Ingår i: Ultrasound in Obstetrics and Gynecology. - : Wiley. - 0960-7692 .- 1469-0705. ; 59:2, s. 241-247
- Relaterad länk:
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http://dx.doi.org/10...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
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- Objective: To describe the clinical and ultrasound characteristics of ovarian carcinosarcoma. Methods: This was a retrospective multicenter study. Patients with a histological diagnosis of ovarian carcinosarcoma, who had undergone preoperative ultrasound examination between 2010 and 2019, were identified from the International Ovarian Tumor Analysis (IOTA) database. Additional patients who were examined outside of the IOTA study were identified from the databases of the participating centers. The masses were described using the terms and definitions of the IOTA group. Additionally, two experienced ultrasound examiners reviewed all available images to identify typical ultrasound features using pattern recognition. Results: Ninety-one patients with ovarian carcinosarcoma who had undergone ultrasound examination were identified, of whom 24 were examined within the IOTA studies and 67 were examined outside of the IOTA studies. Median age at diagnosis was 66 (range, 33–91) years and 84/91 (92.3%) patients were postmenopausal. Most patients (67/91, 73.6%) were symptomatic, with the most common complaint being pain (51/91, 56.0%). Most tumors (67/91, 73.6%) were International Federation of Gynecology and Obstetrics (FIGO) Stage III or IV. Bilateral lesions were observed on ultrasound in 46/91 (50.5%) patients. Ascites was present in 38/91 (41.8%) patients. The median largest tumor diameter was 100 (range, 18–260) mm. All ovarian carcinosarcomas contained solid components, and most were described as solid (66/91, 72.5%) or multilocular-solid (22/91, 24.2%). The median diameter of the largest solid component was 77.5 (range, 11–238) mm. Moderate or rich vascularization was found in 78/91 (85.7%) cases. Retrospective analysis of ultrasound images and videoclips using pattern recognition in 73 cases revealed that all tumors had irregular margins and inhomogeneous echogenicity of the solid components. Forty-seven of 73 (64.4%) masses appeared as a solid tumor with cystic areas. Cooked appearance of the solid tissue was identified in 28/73 (38.4%) tumors. No pathognomonic ultrasound sign of ovarian carcinosarcoma was found. Conclusions: Ovarian carcinosarcomas are usually diagnosed in postmenopausal women and at an advanced stage. The most common ultrasound appearance is a large solid tumor with irregular margins, inhomogeneous echogenicity of the solid tissue and cystic areas. The second most common pattern is a large multilocular-solid mass with inhomogeneous echogenicity of the solid tissue.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)
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- art (ämneskategori)
- ref (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Ciccarone, F.
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Biscione, A.
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Moro, F.
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Fischerova, D.
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Savelli, L.
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Munaretto, M.
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visa fler...
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Jokubkiene, L.
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Sladkevicius, P.
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Chiappa, V.
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Fruscio, R.
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Franchi, D.
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Epstein, E.
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Timmerman, D.
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Froyman, W.
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Valentin, L.
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Scambia, G.
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Testa, A. C.
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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Ultrasound in Ob ...
- Av lärosätet
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Lunds universitet
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Karolinska Institutet