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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005089naa a2200433 4500
001oai:DiVA.org:umu-228567
003SwePub
008240820s2024 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-2285672 URI
0247 a https://doi.org/10.1016/j.amjcard.2024.07.0102 DOI
040 a (SwePub)umu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a for2 swepub-publicationtype
1001 a Bajraktari, Ganiu Umeå universitet,Institutionen för folkhälsa och klinisk medicin,Clinic of Cardiology, University Clinical Centre of Kosova, Kosovo, Prishtina; Medical Faculty, University of Prishtina, Kosovo, Prishtina4 aut0 (Swepub:umu)gaba0006
2451 0a One-month dual antiplatelet therapy reduces major bleeding compared with longer-term treatment without excess stent thrombosis :b a systematic review and meta-analysis of randomized clinical trials
264 1b Elsevier,c 2024
338 a electronic2 rdacarrier
520 a Dual antiplatelet therapy (DAPT) remains the gold standard in patients who underwent percutaneous coronary intervention (PCI). This meta-analysis aims to evaluate the clinical safety of 1-month DAPT followed by aspirin or a P2Y12 receptor inhibitor after PCI with drug-eluting stents (DES). We searched PubMed, MEDLINE, Embase, Scopus, Google Scholar, Cochrane Central Registry, and ClinicalTrials.gov databases and identified 5 randomized controlled trials with 29,831 patients who underwent PCI with DES and compared 1-month versus >1-month DAPT. The primary end point was major bleeding, and the co-primary end point was stent thrombosis. The secondary end point included all-cause mortality, cardiovascular death, myocardial infarction, stroke, and major adverse cardiovascular or cerebrovascular events. Compared with >1-month DAPT, the 1-month DAPT was associated with a lower rate of major bleeding (odds ratio [OR] 0.66, 95% confidence interval [CI] 0.45 to 0.97, p = 0.03, I2 = 71%), whereas stent thrombosis had a similar rate in both study groups (OR 1.08, 95% CI 0.81 to 1.44, p = 0.60, I2 = 0.0%). The study groups had similar risks for all-cause mortality (OR 0.89, 95% CI 0.77 to 1.04, p = 0.14, I2 = 0.0%), cardiovascular death (OR 0.84, 95% CI 0.59 to 1.19, p = 0.32, I2 = 0.0%), myocardial infarction (OR 1.04, 95% CI 0.89 to 1.21, p = 0.62, I2 = 0.0%), and stroke (OR 0.82, 95% CI 0.64 to 1.05, p = 0.11, I2 = 6%). The risk of major adverse cardiovascular or cerebrovascular events was lower (OR 0.86, 95% CI 0.76 to 0.97, p = 0.02, I2 = 25%) in the 1-month DAPT compared with >1-month DAPT. In conclusion, in patients who underwent PCI with DES, 1-month DAPT followed by aspirin or a P2Y12 receptor inhibitor reduced major bleeding with no risk of increased thrombotic risk compared with longer-term DAPT.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng
653 a acute coronary syndrome
653 a dual antiplatelet therapy
653 a percutaneous coronary intervention
653 a stable coronary artery disease
7001 a Bytyci, Ibadeteu Umeå universitet,Institutionen för folkhälsa och klinisk medicin,Clinic of Cardiology, University Clinical Centre of Kosova, Kosovo, Prishtina; Medical Faculty, University of Prishtina, Kosovo, Prishtina4 aut0 (Swepub:umu)ibby0002
7001 a Abdyli, Gencu Clinic of Cardiology, University Clinical Centre of Kosova, Kosovo, Prishtina; Medical Faculty, University of Prishtina, Kosovo, Prishtina4 aut
7001 a Ibrahimi, Pranverau Umeå universitet,Institutionen för folkhälsa och klinisk medicin,Clinic of Cardiology, University Clinical Centre of Kosova, Kosovo, Prishtina4 aut0 (Swepub:umu)prib0001
7001 a Bajraktari, Artanu Umeå universitet,Institutionen för folkhälsa och klinisk medicin,Clinic of Cardiology, University Clinical Centre of Kosova, Kosovo, Prishtina4 aut0 (Swepub:umu)arba0019
7001 a Karahoda, Ronau Department of Pharmacology and Toxicology, Faculty of Pharmacy in Hradec Králové, Charles University, Prague, Czech Republic4 aut
7001 a Elezi, Shpendu Clinic of Cardiology, University Clinical Centre of Kosova, Kosovo, Prishtina; Medical Faculty, University of Prishtina, Kosovo, Prishtina4 aut
7001 a Henein, Michael Y.u Umeå universitet,Institutionen för folkhälsa och klinisk medicin4 aut0 (Swepub:umu)mihe0015
7102 a Umeå universitetb Institutionen för folkhälsa och klinisk medicin4 org
7730 t American Journal of Cardiologyd : Elsevierg 227, s. 91-97q 227<91-97x 0002-9149x 1879-1913
8564 u https://doi.org/10.1016/j.amjcard.2024.07.010y Fulltext
8564 u https://umu.diva-portal.org/smash/get/diva2:1890764/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-228567
8564 8u https://doi.org/10.1016/j.amjcard.2024.07.010

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Bajraktari, Gani
Bytyci, Ibadete
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Karahoda, Rona
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MEDICAL AND HEALTH SCIENCES
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