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Evaluation of Effec...
Evaluation of Effects of Continuous Glucose Monitoring on Physical Activity Habits and Blood Lipid Levels in Persons With Type 1 Diabetes Managed With MDI: An Analysis Based on the GOLD Randomized Trial (GOLD 8)
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- Nyström, Thomas (författare)
- Karolinska Institute
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- Schwarz, Erik (författare)
- Örebro University
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- Dahlqvist, S. (författare)
- Gothenburg University,Göteborgs universitet,University of Gothenburg,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine
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- Wijkman, Magnus O. (författare)
- Linköping University
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- Ekelund, Magnus (författare)
- Lund University,Lunds universitet,Kliniska Vetenskaper, Helsingborg,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Clinical Sciences, Helsingborg,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine
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- Holmer, Helen (författare)
- Centralsjukhuset Kristianstad,Kristianstad Central Hospital,Department of Internal Medicine, Centralsjukhuset, Kristianstad, Sweden,Central Hospital Kristianstad
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- Bolinder, Jan (författare)
- Karolinska universitetssjukhuset,Karolinska University Hospital,Department of Medicine, Karolinska University Hospital Huddinge, Karolinska Institutet, Stockholm, Sweden
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- Hellman, Jarl (författare)
- Uppsala University,Uppsala universitet,Klinisk diabetologi och metabolism
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- Imberg, Henrik, 1991 (författare)
- Gothenburg University,Göteborgs universitet,Chalmers University of Technology,Institutionen för matematiska vetenskaper,Department of Mathematical Sciences
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- Hirsch, Irl B. (författare)
- School of Medicine, University of Washington, Seattle, WA, USA
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- Lind, Marcus, 1976 (författare)
- Gothenburg University,Göteborgs universitet,University of Gothenburg,Sahlgrenska University Hospital,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine
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(creator_code:org_t)
- 2022-06-08
- 2024
- Engelska.
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Ingår i: Journal of diabetes science and technology. - : SAGE Publications. - 1932-2968. ; 18:1, s. 89-98
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Abstract
Ämnesord
Stäng
- Background: People with type 1 diabetes generally view it easier to exercise when having continuous information of the glucose levels. We evaluated whether patients with type 1 diabetes managed with multiple daily insulin injections (MDI) exercised more after initiating continuous glucose monitoring (CGM) and whether the improved glycemic control and well-being associated with CGM translates into improved blood lipids and markers of inflammation. Method: The GOLD trial was a randomized cross-over trial over 16 months where patients used either CGM or capillary self-monitoring of blood glucose (SMBG) over six months, with a four-month wash-out period between the two treatment periods. We compared grade of physical activity, blood lipids, apolipoproteins, and high-sensitivity C-reactive protein (hsCRP) levels during CGM and SMBG. Results: There were 116 patients with information of physical activity estimated by the International Physical Activity Questionnaire (IPAQ) during both CGM and SMBG. No changes were found during CGM or SMBG, IPAQ scores 3305 versus 3878 (P =.16). In 136 participants with information of blood lipid levels with no change in lipid-lowering medication during the two treatment periods, HbA1c differed by 4.2 mmol/mol (NGSP 0.39%) between SMBG and CGM treatment (P <.001). No significant changes existed in low-density lipoprotein, high-density lipoprotein, triglycerides, total cholesterol, apolipoprotein A1, apolipoprotein B1, or hsCRP, during CGM and SMBG. Conclusion: Although many patients experience it easier to perform physical activity when monitoring glucose levels with CGM, it does not influence the amount of physical activity in persons with type 1 diabetes. Blood lipids, apolipoprotein, and hsCRP levels were similar during CGM and SMBG.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Sjukgymnastik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Physiotherapy (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Allmänmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- General Practice (hsv//eng)
Nyckelord
- hypoglycemia
- low-grade inflammation
- blood lipids
- continuous glucose monitoring
- physical activity
- Internal Medicine
- Medicin
- blood lipids
- continuous glucose monitoring
- hypoglycemia
- low-grade inflammation
- physical activity
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
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Nyström, Thomas
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Schwarz, Erik
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Dahlqvist, S.
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Wijkman, Magnus ...
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Ekelund, Magnus
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Holmer, Helen
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visa fler...
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Bolinder, Jan
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Hellman, Jarl
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Imberg, Henrik, ...
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Hirsch, Irl B.
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Lind, Marcus, 19 ...
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Hälsovetenskap
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och Sjukgymnastik
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Endokrinologi oc ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Allmänmedicin
- Artiklar i publikationen
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Journal of diabe ...
- Av lärosätet
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Chalmers tekniska högskola
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Uppsala universitet
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Lunds universitet
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Göteborgs universitet