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Sesame oil and vita...
Sesame oil and vitamin E co-administration may improve cardiometabolic risk factors in patients with metabolic syndrome: a randomized clinical trial
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- Farajbakhsh, Ali (författare)
- Shiraz University of Medical Sciences
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- Mazloomi, Seyed Mohammad (författare)
- Shiraz University of Medical Sciences
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- Mazidi, Mohsen, 1989 (författare)
- Chalmers tekniska högskola,Chalmers University of Technology
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- Rezaie, Peyman (författare)
- University of Adelaide
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- Akbarzadeh, Marzieh (författare)
- Shiraz University of Medical Sciences
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- Ahmad, Saeedeh Poor (författare)
- Shiraz University of Medical Sciences
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Ferns, G. A. (författare)
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- Ofori-Asenso, Richard (författare)
- Monash University
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- Babajafari, Siavash (författare)
- Shiraz University of Medical Sciences
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(creator_code:org_t)
- 2019-05-14
- 2019
- Engelska.
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Ingår i: European Journal of Clinical Nutrition. - : Springer Science and Business Media LLC. - 0954-3007 .- 1476-5640. ; 73:10, s. 1403-1411
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https://research.cha...
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https://doi.org/10.1...
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Abstract
Ämnesord
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- Objectives: Metabolic syndrome (MetS) represents a clustering of metabolic abnormalities that are associated with an increased risk of type 2 diabetes and cardiovascular disease. We aimed to evaluate the effects of sesame oil enriched with vitamin E (vit E), sesame oil alone and sunflower oil on lipid profile, fasting blood glucose (FBG), malondialdehyde (MDA), high-sensitivity C-reactive protein (Hs-CRP), homeostatic model assessment (HOMA-IR), and blood pressure (BP) in patients with MetS. Subjects: Overall, 75 individuals with MetS (aged 30–70 years) participated in this randomized, single-blind controlled trial. Patients were randomly allocated to: (1) Group A (n = 25): sesame oil (30 ml/day) enriched with vit E (400 mg/day), (2) Group B (n = 25): sesame oil (30 ml/day), (3) Group C (n = 25): sunflower oil (30 ml/day). Anthropometric data, dietary intake, blood pressure, and biochemical markers, including fasting serum lipids, FBG, serum insulin, MDA, and hs-CRP were measured at baseline and at week 8. Results: In individuals in the sesame oil enriched with vit E group (Group A), there were significant reductions in serum total cholesterol (TC), triglycerides (TG), FBG, HOMA-IR, MDA, hs-CRP, high-density lipoprotein (HDL-C) systolic and diastolic BP (for all the comparison p < 0.02). Similarly, in Group B (taking sesame oil alone), TC, TG, FBG, HOMA-IR, MDA, systolic and diastolic BP were significantly improved (for all the comparison p < 0.025), while there were no significant changes in serum HDL (baseline = 35.9 ± 7.2 mg/dL vs. 36.4 ± 6.2 mg/dL, p = 0.432) and hs-CRP (baseline = 4.38 ± 1.34 mg/dL vs. week 8 = 3.96 ± 1.7 mg/dL, p = 0.057) in second group. No significant changes in any of the studied clinical and anthropometric data were found in Group C (on sunflower oil). Conclusion: Sesame oil (±vit E) was shown to beneficially affect several cardiometabolic indices (including lipids, FBG, BP, HOMA-IR, and MDA) in patients with MetS.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Annan klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Other Clinical Medicine (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- sesamum
- insulin
- triacylglycerol
- biochemical marker
- sesame oil
- high density lipoprotein cholesterol
- glucose
- C reactive protein
- alpha tocopherol
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Farajbakhsh, Ali
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Mazloomi, Seyed ...
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Mazidi, Mohsen, ...
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Rezaie, Peyman
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Akbarzadeh, Marz ...
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Ahmad, Saeedeh P ...
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visa fler...
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Ferns, G. A.
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Ofori-Asenso, Ri ...
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Babajafari, Siav ...
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visa färre...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Annan klinisk me ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Kardiologi
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Chalmers tekniska högskola