Genetic dissection of complex traits / edited by D.C. Rao, C. Charles Gu.

• 1. An overview of the genetic dissection of complex traits / D. C. Rao -- 2. Familial resemblance and heritability / Treva K. Rice -- 3. Linkage and association: basic concepts / Ingrid B. Borecki and Michael A. Province -- 4. Definition of phenotype / 5. Genotyping platforms for mass-throughput genotyping with SNPs, including human genome-wide scans / Karen Maresso and Ulrich Broeckel -- 6. Genotyping errors and their impact on genetic analysis / Michael B. Miller, Karen Schwander, and D. C. Rhao -- 7. Model-based methods for linkage analysis / John P. Rice, Nancy L. Saccone, and Jonathan Corbett -- 8. Contemporary model-free methods for linkage analysis / Laura Almasy and John Blangero -- 9. DNA sequence-based phenotypic association analysis / Nicholas J. Schork, Jennifer Wessel, and Nathalie Malo --. 
• 10. Family-based methods for linkage and association analysis / Nan M. Laird and Christoph Lange -- 11. Searching for additional disease loci in a genomic region / Glenys Thomson, Lisa F. Barcellos, and Ana M. Valdes -- 12. Methods for handling multiple testing / Treva K. Rice, Nicholas J. Schork, and D. C. Rao -- 13. Meta-analysis methods / Thomas A. Trikalinos, Georgia Salanti, Eias Zintzaras, and John P. A. Ioannidis -- 14. Haplotype-association analysis / Nianjun Liu, Kui Zhang, and Hongyu Zhao -- 15. Characterization LD structures and the utility of HapMap in genetic association studies / C. Charles Gu, Kai Yu, and D. C. Rao -- 16. Associations among multiple markers and complex disease: models, algorithms, and applications / Themistocles L. Assimes, Adam B. Olshen, Balasubramanian Narasimhan, and Richard A. Olshen --. 
• 17. Study designs for genome-wide association studies / Peter Kraft and David G. Cox -- 18. Ethical, legal, and social implications of biobanks for genetics research / Susanne B. Haga and Laura M. Beskow -- 19. Admixture mapping and the role of population structure for localizing disease genes / Xiaofeng Zhu, Hua Tang, and Neil Risch -- 20. Integrating global gene expression analysis and genetics / Clarles R. Farber and Aldons J. Lusis -- 21. A systems biology approach to drug discovery / Jun Zhu, Bin Zhang, and Eric E. Schadt -- 22. The promise of composite likelihood methods for addressing computationally intensive challenges / Na Li -- 23 Comparative genomics for detecting human disease genes / Carol Moreno, Jozef Lazar, Howard J. Jacob, and Anne E. Kwitek -- 24. From genetics to mechanism of disease liability / Andreas Rohrwasser, Paul Lott, Robert B. Weiss, and Jean-Marc Lalouel -- 25. Into the Post-HapMap era / Newton E. Morton.

Ämnesord

Medical genetics  (LCSH)

Genetic epidemiology  (LCSH)

Syndromes  -- Genetic aspects (LCSH)

Publikations- och innehållstyp

QH431.A1 (LCC)

RB155 (NAL)

616.042 (DDC)

Vaa (kssb/8 (machine generated))