The genetic component to diabetes / Nancy J. Cox.

• Contents: Diabetes mellitus: definition, classification and its use as a model for genetic studies of complex disorders -- Genetic forms of diabetes mellitus: monogenic and polygenic -- Identification of diabetes genes -- Monogenic forms of diabetes: human HNF-1-alpha/MODY3 gene -- Polygenic forms of diabetes -- HLA and ISN in type 1 diabetes -- Genes for type 2 diabetes and linkage mapping -- TCF7L2 in type 2 diabetes -- Genome wide association studies and gene loci implicated in these studies -- Allelic variation in human gene expression -- Ancestral susceptibility models.

Ämnesord

Genetics, Population.  (MeSH)