SwePub
Sök i LIBRIS databas

  Extended search

WFRF:(Nizankowska Mogilnicka Ewa)
 

Search: WFRF:(Nizankowska Mogilnicka Ewa) > Dietary Intake of F...

Dietary Intake of Flavonoids and Ventilatory Function in European Adults A GA²LEN Study

Garcia-Larsen, Vanessa (author)
Thawer, Narjis (author)
Charles, David (author)
show more...
Cassidy, Aedin (author)
van Zele, Thibaut (author)
Thilsing, Trine (author)
Ahlström, Matti (author)
Haahtela, Tari (author)
Keil, Thomas (author)
Matricardi, Paolo M (author)
Brożek, Grzegorz (author)
Kowalski, Marek L (author)
Makowska, Joanna (author)
Niżankowska-Mogilnicka, Ewa (author)
Rymarczyk, Barbara (author)
Loureiro, Carlos (author)
Todo Bom, Ana (author)
Bachert, Claus (author)
Forsberg, Bertil (author)
Janson, Christer (author)
Torén, Kjell (author)
Potts, James F (author)
Burney, Peter Gj (author)
show less...
 (publisher)
MDPI AG 2018
2018
English.
In: Nutrients. - 2072-6643. ; 10:1
  • swepub:Mat__t
Abstract Subject headings
Close  
  • BACKGROUND: Flavonoids exert anti-inflammatory properties and modulate oxidative stress in vitro, suggesting a protective effect on lung function, but epidemiological studies examining this association are scarce. METHODS: A stratified random sample was drawn from the GA²LEN screening survey, in which 55,000 adults aged 15 to 75 answered a questionnaire on respiratory symptoms. Post-bronchodilator spirometry was obtained from 2850 subjects. Forced vital capacity (FVC), the ratio between the forced exhaled volume in 1 second (FEV₁) and FVC (FEV₁/FVC), FVC below lower limit of normal (FVC < LLN), and FEV₁/FVC < LLN were calculated. Intake of the six main subclasses of flavonoids was estimated using the GA²LEN Food Frequency Questionnaire. Adjusted associations between outcomes and each subclass of flavonoids were examined with multivariate regressions. Simes' procedure was used to test for multiple comparisons. RESULTS: A total of 2599 subjects had valid lung function and dietary data. A lower prevalence of FVC < LLN (airway restriction) was observed in those with higher total flavonoid (adjusted odds ratio (aOR), higher vs. lowest quintile intake 0.58; 95% Confidence Interval (CI) 0.36, 0.94), and pro-anthocyanidin intakes (aOR 0.47; 95% CI 0.27, 0.81). A higher FEV₁/FVC was associated with higher intakes of total flavonoids and pro-anthocyanidins (adjusted correlation coefficient (a β-coeff 0.33; 0.10, 0.57 and a β-coeff 0.44; 95% CI 0.19, 0.69, respectively). After Simes' procedure, the statistical significance of each of these associations was attenuated but remained below 0.05, with the exception of total flavonoids and airway restriction. CONCLUSIONS: This population-based study in European adults provides cross-sectional evidence of a positive association of total flavonoid intake and pro-anthocyanidins and ventilatory function, and a negative association with spirometric restriction in European adults.

Subject headings

Medical and Health Sciences  (hsv)
Health Sciences  (hsv)
Nutrition and Dietetics  (hsv)
Medicin och hälsovetenskap  (hsv)
Hälsovetenskaper  (hsv)
Näringslära  (hsv)

Keyword

flavonoids
pro-anthocyanidins
lung function
GA2LEN

Find in a library

  • Nutrients (Search for host publication in LIBRIS)

To the university's database

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Close

Copy and save the link in order to return to this view