WFRF:(Salami Alireza)
Sökning: WFRF:(Salami Alireza) > Physical activity o...
LIBRIS Formathandbok (Information om MARC21)
| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 04359naa a22006733a 4500 | |
| 001 | 19660716 | |
| 003 | SE-LIBR | |
| 005 | 20160906175621.0 | |
| 007 | cr|||||||||||| | |
| 008 | 160906s2016 sw |||| o |||| ||eng c | |
| 024 | 7 | a http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1124472 uri |
| 024 | 7 | a urn:nbn:se:umu:diva-1124472 urn |
| 024 | 7 | a 10.1016/j.neuroimage.2015.12.0102 doi |
| 040 | a S | |
| 041 | 0 | a eng |
| 042 | 9 EPLK | |
| 100 | 1 | a Boraxbekk, Carl-Johand 1980-4 aut |
| 245 | 1 0 | a Physical activity over a decade modifies age-related decline in perfusion, gray matter volume, and functional connectivity of the posterior default mode networkh [Elektronisk resurs]b a multimodal approach |
| 260 | b Elsevierc 2016 | |
| 500 | a Published | |
| 500 | a | |
| 506 | 0 | a gratis |
| 520 | a One step toward healthy brain aging may be to entertain a physically active lifestyle. Studies investigating physical activity effects on brain integrity have, however, mainly been based on single brain markers, and few used a multimodal imaging approach. In the present study, we used cohort data from the Betula study to examine the relationships between scores reflecting current and accumulated physical activity and brain health. More specifically, we first examined if physical activity scores modulated negative effects of age on seven resting state networks previously identified by Salami, Pudas, and Nyberg (2014). The results revealed that one of the most age-sensitive RSN was positively altered by physical activity, namely, the posterior default-mode network involving the posterior cingulate cortex (PCC). Second, within this physical activity-sensitive RSN, we further analyzed the association between physical activity and gray matter (GM) volumes, white matter integrity, and cerebral perfusion using linear regression models. Regions within the identified DMN displayed larger GM volumes and stronger perfusion in relation to both current and 10-years accumulated scores of physical activity. No associations of physical activity and white matter integrity were observed. Collectively, our findings demonstrate strengthened PCC–cortical connectivity within the DMN, larger PCC GM volume, and higher PCC perfusion as a function of physical activity. In turn, these findings may provide insights into the mechanisms of how long-term regular exercise can contribute to healthy brain aging. | |
| 650 | 7 | a Medical and Health Sciences2 hsv |
| 650 | 7 | a Basic Medicine2 hsv |
| 650 | 7 | a Neurosciences2 hsv |
| 650 | 7 | a Medicin och hälsovetenskap2 hsv |
| 650 | 7 | a Medicinska grundvetenskaper2 hsv |
| 650 | 7 | a Neurovetenskaper2 hsv |
| 650 | 7 | a Medical and Health Sciences2 hsv |
| 650 | 7 | a Clinical Medicine2 hsv |
| 650 | 7 | a Radiology, Nuclear Medicine and Medical Imaging2 hsv |
| 650 | 7 | a Medicin och hälsovetenskap2 hsv |
| 650 | 7 | a Klinisk medicin2 hsv |
| 650 | 7 | a Radiologi och bildbehandling2 hsv |
| 653 | 0 | a Physical activity |
| 653 | 0 | a Resting state networks |
| 653 | 0 | a fMRI |
| 653 | 0 | a DMN |
| 653 | 0 | a Perfusion |
| 700 | 1 | a Salami, Alireza4 aut |
| 700 | 1 | a Wåhlin, Anders4 aut |
| 700 | 1 | a Nyberg, Lars4 aut |
| 710 | 1 | a Umeå universitetb Samhällsvetenskapliga fakulteten4 pbl |
| 710 | 1 | a Umeå universitetb Medicinska fakulteten4 pbl0 268483 |
| 710 | 1 | a Umeå universitetb Medicinska fakulteten4 pbl0 268483 |
| 710 | 1 | a Umeå universitetb Medicinska fakulteten4 pbl0 268483 |
| 710 | 1 | a Umeå universitetb Medicinska fakulteten4 pbl0 268483 |
| 772 | 1 8 | i channel recordw 18813935 |
| 773 | 0 | i Värdpublikationt NeuroImageg 131, 133-141x 1053-8119 |
| 856 | 4 0 | u http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-112447 |
| 856 | 4 0 | u http://dx.doi.org/10.1016/j.neuroimage.2015.12.010 |
| 856 | 4 0 | u http://umu.diva-portal.org/smash/get/diva2:877742/FULLTEXT01 |
| 910 | 2 s | 6 710,710,710,710a Umeå universitet.b Medicinsk-odontologiska fakultetenu Umeå universitet.b Medicinska fakulteten |
| 910 | 2 s | 6 710,710,710,710a Medicinska fakulteten vid Umeå universitetu Umeå universitet.b Medicinska fakulteten |
| 841 | 5 APISa x ab 160906||0000|||||001||||||000000e 1 | |
| 024 | 7 | 5 APISa urn:nbn:se:umu:diva-1124472 urn |
| 852 | 5 APISb APIS | |
| 856 | 4 0 | 5 APISu http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-112447 |
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