WFRF:(Arriola Larraitz)
Sökning: WFRF:(Arriola Larraitz) > HbA(1c) Measured in...
LIBRIS Formathandbok (Information om MARC21)
| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 04678naa a22007453a 4500 | |
| 001 | 22105723 | |
| 003 | SE-LIBR | |
| 005 | 20171212084419.0 | |
| 007 | cr|||||||||||| | |
| 008 | 171212s2012 sw |||| o |||| ||eng c | |
| 024 | 7 | a http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-573632 uri |
| 024 | 7 | a urn:nbn:se:umu:diva-573632 urn |
| 024 | 7 | a 10.1371/journal.pone.00388772 doi |
| 040 | a S | |
| 041 | 0 | a eng |
| 042 | 9 EPLK | |
| 100 | 1 | a Sluik, Diewertje4 aut |
| 245 | 1 0 | a HbA(1c) Measured in Stored Erythrocytes Is Positively Linearly Associated with Mortality in Individuals with Diabetes Mellitush [Elektronisk resurs] |
| 260 | c 2012 | |
| 500 | a Published | |
| 506 | 0 | a gratis |
| 520 | a Introduction: Observational studies have shown that glycated haemoglobin (HbA(1c)) is related to mortality, but the shape of the association is less clear. Furthermore, disease duration and medication may modify this association. This observational study explored the association between HbA(1c) measured in stored erythrocytes and mortality. Secondly, it was assessed whether disease duration and medication use influenced the estimates or were independently associated with mortality. Methods: Within the European Prospective Investigation into Cancer and Nutrition a cohort was analysed of 4,345 individuals with a confirmed diagnosis of diabetes at enrolment. HbA(1c) was measured in blood samples stored up to 19 years. Multivariable Cox proportional hazard regression models for all-cause mortality investigated HbA(1c) in quartiles as well as per 1% increment, diabetes medication in seven categories of insulin and oral hypoglycaemic agents, and disease duration in quartiles. Results: After a median follow-up of 9.3 years, 460 participants died. Higher HbA(1c) was associated with higher mortality: Hazard Ratio for 1%-increase was 1.11 (95% CI 1.06, 1.17). This association was linear (P-nonlinearity = 0.15) and persistent across categories of medication use, disease duration, and co-morbidities. Compared with metformin, other medication types were not associated with mortality. Longer disease duration was associated with mortality, but not after adjustment for HbA(1c) and medication. Conclusion: This prospective study showed that persons with lower HbA(1c) had better survival than those with higher HbA(1c). The association was linear and independent of disease duration, type of medication use, and presence of co-morbidities. Any improvement of HbA(1c) appears to be associated with reduced mortality risk. | |
| 650 | 7 | a Medical and Health Sciences2 hsv |
| 650 | 7 | a Clinical Medicine2 hsv |
| 650 | 7 | a Endocrinology and Diabetes2 hsv |
| 650 | 7 | a Medicin och hälsovetenskap2 hsv |
| 650 | 7 | a Klinisk medicin2 hsv |
| 650 | 7 | a Endokrinologi och diabetes2 hsv |
| 700 | 1 | a Boeing, Heiner4 aut |
| 700 | 1 | a Montonen, Jukka4 aut |
| 700 | 1 | a Kaaks, Rudolf4 aut |
| 700 | 1 | a Lukanova, Annekatrin4 aut |
| 700 | 1 | a Sandbaek, Annelli4 aut |
| 700 | 1 | a Overvad, Kim4 aut |
| 700 | 1 | a Arriola, Larraitz4 aut |
| 700 | 1 | a Ardanaz, Eva4 aut |
| 700 | 1 | a Saieva, Calogero4 aut |
| 700 | 1 | a Grioni, Sara4 aut |
| 700 | 1 | a Tumino, Rosario4 aut |
| 700 | 1 | a Sacerdote, Carlotta4 aut |
| 700 | 1 | a Mattiello, Amalia4 aut |
| 700 | 1 | a Spijkerman, Annemieke M. W.4 aut |
| 700 | 1 | a van der A, Daphne L.4 aut |
| 700 | 1 | a Beulens, Joline W. J.4 aut |
| 700 | 1 | a van Dieren, Susan4 aut |
| 700 | 1 | a Nilsson, Peter M.4 aut |
| 700 | 1 | a Groop, Leif C.4 aut |
| 700 | 1 | a Franks, Paul W.4 aut |
| 700 | 1 | a Rolandsson, Olov4 aut |
| 700 | 1 | a Bueno-de-Mesquita, Bas4 aut |
| 700 | 1 | a Noethlings, Ute4 aut |
| 710 | 1 2 | a Umeå universitetb Medicinska fakulteten4 pbl0 268483 |
| 710 | 1 2 | a Umeå universitetb Medicinska fakulteten4 pbl0 268483 |
| 710 | 1 2 | a Umeå universitetb Medicinska fakulteten4 pbl0 268483 |
| 772 | 1 8 | i channel recordw 18813935 |
| 773 | 0 8 | i Värdpublikationt PLoS ONEg 7:6, e38877x 1932-6203 |
| 856 | 4 0 | u http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-57363 |
| 856 | 4 0 | u http://dx.doi.org/10.1371/journal.pone.0038877 |
| 856 | 4 0 | u http://umu.diva-portal.org/smash/get/diva2:541420/FULLTEXT02 |
| 910 | 2 s | 6 710,710,710a Umeå universitet.b Medicinsk-odontologiska fakultetenu Umeå universitet.b Medicinska fakulteten |
| 910 | 2 s | 6 710,710,710a Medicinska fakulteten vid Umeå universitetu Umeå universitet.b Medicinska fakulteten |
| 841 | 5 APISa x ab 171212||0000|||||001||||||000000e 1 | |
| 024 | 7 | 5 APISa urn:nbn:se:umu:diva-573632 urn |
| 852 | 5 APISb APIS | |
| 856 | 4 0 | 5 APISu http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-57363 |
Hitta mer i SwePub
- Av författaren/redakt...
- Sluik, Diewertje
- Boeing, Heiner
- Montonen, Jukka
- Kaaks, Rudolf
- Lukanova, Anneka ...
- Sandbaek, Annell ...
- visa fler...
- Overvad, Kim
- Arriola, Larrait ...
- Ardanaz, Eva
- Saieva, Calogero
- Grioni, Sara
- Tumino, Rosario
- Sacerdote, Carlo ...
- Mattiello, Amali ...
- Spijkerman, Anne ...
- van der A, Daphn ...
- Beulens, Joline ...
- van Dieren, Susa ...
- Nilsson, Peter M ...
- Groop, Leif C.
- Franks, Paul W.
- Rolandsson, Olov
- Bueno-de-Mesquit ...
- Noethlings, Ute
- visa färre...
- Av lärosätet
- Swepub_uni:_t
Sök utanför SwePub
- Sök vidare i:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - Nationella bibliotekssystem
- LIBRIS.kb.se
