Sökning: WFRF:(Black Amanda) > Genome-wide associa...
Fältnamn | Indikatorer | Metadata |
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000 | 07299naa a22019093a 4500 | |
001 | 20879839 | |
003 | SE-LIBR | |
005 | 20170629204434.0 | |
007 | cr|||||||||||| | |
008 | 170629s2017 sw |||| o |||| ||eng c | |
024 | 7 | a http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1370382 uri |
024 | 7 | a urn:nbn:se:umu:diva-1370382 urn |
024 | 7 | a 10.1038/ncomms157242 doi |
040 | a S | |
041 | 0 | a eng |
042 | 9 EPLK | |
100 | 1 | a Scelo, Ghislaine4 aut |
245 | 1 0 | a Genome-wide association study identifies multiple risk loci for renal cell carcinomah [Elektronisk resurs] |
260 | b NATURE PUBLISHING GROUPc 2017 | |
500 | a Published | |
506 | 0 | a gratis |
520 | a Previous genome-wide association studies (GWAS) have identified six risk loci for renal cell carcinoma (RCC). We conducted a meta-analysis of two new scans of 5,198 cases and 7,331 controls together with four existing scans, totalling 10,784 cases and 20,406 controls of European ancestry. Twenty-four loci were tested in an additional 3,182 cases and 6,301 controls. We confirm the six known RCC risk loci and identify seven new loci at 1p32.3 (rs4381241, P = 3.1 x 10(-10)), 3p22.1 (rs67311347, P = 2.5 x 10(-8)), 3q26.2 (rs10936602, P = 8.8 x 10(-9)), 8p21.3 (rs2241261, P = 5.8 x 10(-9)), 10q24.33-q25.1 (rs11813268, P = 3.9 x 10(-8)), 11q22.3 (rs74911261, P = 2.1 x 10(-10)) and 14q24.2 (rs4903064, P = 2.2 x 10(-24)). Expression quantitative trait analyses suggest plausible candidate genes at these regions that may contribute to RCC susceptibility. | |
650 | 7 | a Medical and Health Sciences2 hsv |
650 | 7 | a Clinical Medicine2 hsv |
650 | 7 | a Urology and Nephrology2 hsv |
650 | 7 | a Medicin och hälsovetenskap2 hsv |
650 | 7 | a Klinisk medicin2 hsv |
650 | 7 | a Urologi och njurmedicin2 hsv |
700 | 1 | a Purdue, Mark P.4 aut |
700 | 1 | a Brown, Kevin M.4 aut |
700 | 1 | a Johansson, Mattias4 aut |
700 | 1 | a Wang, Zhaoming4 aut |
700 | 1 | a Eckel-Passow, Jeanette E.4 aut |
700 | 1 | a Ye, Yuanqing4 aut |
700 | 1 | a Hofmann, Jonathan N.4 aut |
700 | 1 | a Choi, Jiyeon4 aut |
700 | 1 | a Foll, Matthieu4 aut |
700 | 1 | a Gaborieau, Valerie4 aut |
700 | 1 | a Machiela, Mitchell J.4 aut |
700 | 1 | a Colli, Leandro M.4 aut |
700 | 1 | a Li, Peng4 aut |
700 | 1 | a Sampson, Joshua N.4 aut |
700 | 1 | a Abedi-Ardekani, Behnoush4 aut |
700 | 1 | a Besse, Celine4 aut |
700 | 1 | a Blanche, Helene4 aut |
700 | 1 | a Boland, Anne4 aut |
700 | 1 | a Burdette, Laurie4 aut |
700 | 1 | a Chabrier, Amelie4 aut |
700 | 1 | a Durand, Geoffroy4 aut |
700 | 1 | a Le Calvez-Kelm, Florence4 aut |
700 | 1 | a Prokhortchouk, Egor4 aut |
700 | 1 | a Robinot, Nivonirina4 aut |
700 | 1 | a Skryabin, Konstantin G.4 aut |
700 | 1 | a Wozniak, Magdalena B.4 aut |
700 | 1 | a Yeager, Meredith4 aut |
700 | 1 | a Basta-Jovanovic, Gordana4 aut |
700 | 1 | a Dzamic, Zoran4 aut |
700 | 1 | a Foretova, Lenka4 aut |
700 | 1 | a Holcatova, Ivana4 aut |
700 | 1 | a Janout, Vladimir4 aut |
700 | 1 | a Mates, Dana4 aut |
700 | 1 | a Mukeriya, Anush4 aut |
700 | 1 | a Rascu, Stefan4 aut |
700 | 1 | a Zaridze, David4 aut |
700 | 1 | a Bencko, Vladimir4 aut |
700 | 1 | a Cybulski, Cezary4 aut |
700 | 1 | a Fabianova, Eleonora4 aut |
700 | 1 | a Jinga, Viorel4 aut |
700 | 1 | a Lissowska, Jolanta4 aut |
700 | 1 | a Lubinski, Jan4 aut |
700 | 1 | a Navratilova, Marie4 aut |
700 | 1 | a Rudnai, Peter4 aut |
700 | 1 | a Szeszenia-Dabrowska, Neonila4 aut |
700 | 1 | a Benhamou, Simone4 aut |
700 | 1 | a Cancel-Tassin, Geraldine4 aut |
700 | 1 | a Cussenot, Olivier4 aut |
700 | 1 | a Baglietto, Laura4 aut |
700 | 1 | a Boeing, Heiner4 aut |
700 | 1 | a Khaw, Kay-Tee4 aut |
700 | 1 | a Weiderpass, Elisabete4 aut |
700 | 1 | a Ljungberg, Börje4 aut |
700 | 1 | a Sitaram, Raviprakash T.4 aut |
700 | 1 | a Bruinsma, Fiona4 aut |
700 | 1 | a Jordan, Susan J.4 aut |
700 | 1 | a Severi, Gianluca4 aut |
700 | 1 | a Winship, Ingrid4 aut |
700 | 1 | a Hveem, Kristian4 aut |
700 | 1 | a Vatten, Lars J.4 aut |
700 | 1 | a Fletcher, Tony4 aut |
700 | 1 | a Koppova, Kvetoslava4 aut |
700 | 1 | a Larsson, Susanna C.4 aut |
700 | 1 | a Wolk, Alicja4 aut |
700 | 1 | a Banks, Rosamonde E.4 aut |
700 | 1 | a Selby, Peter J.4 aut |
700 | 1 | a Easton, Douglas F.4 aut |
700 | 1 | a Pharoah, Paul4 aut |
700 | 1 | a Andreotti, Gabriella4 aut |
700 | 1 | a Freeman, Laura E. Beane4 aut |
700 | 1 | a Koutros, Stella4 aut |
700 | 1 | a Albanes, Demetrius4 aut |
700 | 1 | a Mannisto, Satu4 aut |
700 | 1 | a Weinstein, Stephanie4 aut |
700 | 1 | a Clark, Peter E.4 aut |
700 | 1 | a Edwards, Todd L.4 aut |
700 | 1 | a Lipworth, Loren4 aut |
700 | 1 | a Gapstur, Susan M.4 aut |
700 | 1 | a Stevens, Victoria L.4 aut |
700 | 1 | a Carol, Hallie4 aut |
700 | 1 | a Freedman, Matthew L.4 aut |
700 | 1 | a Pomerantz, Mark M.4 aut |
700 | 1 | a Cho, Eunyoung4 aut |
700 | 1 | a Kraft, Peter4 aut |
700 | 1 | a Preston, Mark A.4 aut |
700 | 1 | a Wilson, Kathryn M.4 aut |
700 | 1 | a Gaziano, J. Michael4 aut |
700 | 1 | a Sesso, Howard D.4 aut |
700 | 1 | a Black, Amanda4 aut |
700 | 1 | a Freedman, Neal D.4 aut |
700 | 1 | a Huang, Wen-Yi4 aut |
700 | 1 | a Anema, John G.4 aut |
700 | 1 | a Kahnoski, Richard J.4 aut |
700 | 1 | a Lane, Brian R.4 aut |
700 | 1 | a Noyes, Sabrina L.4 aut |
700 | 1 | a Petillo, David4 aut |
700 | 1 | a Teh, Bin Tean4 aut |
700 | 1 | a Peters, Ulrike4 aut |
700 | 1 | a White, Emily4 aut |
700 | 1 | a Anderson, Garnet L.4 aut |
700 | 1 | a Johnson, Lisa4 aut |
700 | 1 | a Luo, Juhua4 aut |
700 | 1 | a Buring, Julie4 aut |
700 | 1 | a Lee, I-Min4 aut |
700 | 1 | a Chow, Wong-Ho4 aut |
700 | 1 | a Moore, Lee E.4 aut |
700 | 1 | a Wood, Christopher4 aut |
700 | 1 | a Eisen, Timothy4 aut |
700 | 1 | a Henrion, Marc4 aut |
700 | 1 | a Larkin, James4 aut |
700 | 1 | a Barman, Poulami4 aut |
700 | 1 | a Leibovich, Bradley C.4 aut |
700 | 1 | a Choueiri, Toni K.4 aut |
700 | 1 | a Lathrop, G. Mark4 aut |
700 | 1 | a Rothman, Nathaniel4 aut |
700 | 1 | a Deleuze, Jean-Francois4 aut |
700 | 1 | a Mckay, James D.4 aut |
700 | 1 | a Parker, Alexander S.4 aut |
700 | 1 | a Wu, Xifeng4 aut |
700 | 1 | a Houlston, Richard S.4 aut |
700 | 1 | a Brennan, Paul4 aut |
700 | 1 | a Chanock, Stephen J.4 aut |
710 | 1 2 | a Umeå universitetb Medicinska fakulteten4 pbl0 268483 |
772 | 1 8 | i channel recordw 18813935 |
773 | 0 8 | i Värdpublikationt Nature Communicationsg 8x 2041-1723 |
856 | 4 0 | u http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-137038 |
856 | 4 0 | u http://dx.doi.org/10.1038/ncomms15724 |
856 | 4 0 | u http://umu.diva-portal.org/smash/get/diva2:1117165/FULLTEXT01 |
910 | 2 s | 6 710a Umeå universitet.b Medicinsk-odontologiska fakultetenu Umeå universitet.b Medicinska fakulteten |
910 | 2 s | 6 710a Medicinska fakulteten vid Umeå universitetu Umeå universitet.b Medicinska fakulteten |
841 | 5 APISa x ab 170629||0000|||||001||||||000000e 1 | |
024 | 7 | 5 APISa urn:nbn:se:umu:diva-1370382 urn |
852 | 5 APISb APIS | |
856 | 4 0 | 5 APISu http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-137038 |
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