Segmentation-based Deep Learning Fundus Image Analysis

• Diabetic retinopathy is the most common cause of new cases of blindness in people of working age. Early diagnosis is the key to slowing the progression of the disease, thus preventing blindness. Retinal fundus images form an important basis for judging these retinal diseases. To the best of our knowledge, no prior studies have scrutinized the predictive power of the different compositions of retinal images using deep learning. This paper is to investigate whether there exists specific region that could assist in better prediction of the retinopathy disease, meaning to find the best region in fundus images that can boost the prediction power of models for retinopathy classification. To this end, with image segmentation techniques, the fundus image is divided into three different segments, namely, the optic disc, the blood vessels, and the other regions (regions other than blood vessels and optic disk). These regions are then contrasted against the performance of original fundus images. The convolutional neural network as well as transfer deep learning with the state-of-the-art pre-trained models (i.e., AlexNet, GoogleNet, Resnet50, VGG19) are deployed. We report the average of ten runs for each model. Different machine learning evaluation metrics are used. The other regions' segment reveals more predictive power than the original fundus image especially when using AlexNet/Resnet50.

Subject headings

TEKNIK OCH TEKNOLOGIER  -- Medicinteknik -- Medicinsk bildbehandling (hsv//swe)

ENGINEERING AND TECHNOLOGY  -- Medical Engineering -- Medical Image Processing (hsv//eng)

TEKNIK OCH TEKNOLOGIER  -- Elektroteknik och elektronik -- Signalbehandling (hsv//swe)

ENGINEERING AND TECHNOLOGY  -- Electrical Engineering, Electronic Engineering, Information Engineering -- Signal Processing (hsv//eng)

TEKNIK OCH TEKNOLOGIER  -- Elektroteknik och elektronik -- Datorsystem (hsv//swe)

ENGINEERING AND TECHNOLOGY  -- Electrical Engineering, Electronic Engineering, Information Engineering -- Computer Systems (hsv//eng)

Keyword

AlexNet

Deep Learning

Fundus Image

Image Segmentation

Retinopathy

Publication and Content Type

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