id:"swepub:oai:DiVA.org:du-22659"
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- Wändell, PerKarolinska Institutet (author)
Warfarin treatment and risk of stroke among primary care patients with atrial fibrillation
- Article/chapterEnglish2016
Publisher, publication year, extent ...
- 2016-08-18
- Informa UK Limited,2016
- printrdacarrier
Numbers
- LIBRIS-ID:oai:DiVA.org:du-22659
- https://urn.kb.se/resolve?urn=urn:nbn:se:du-22659URI
- https://doi.org/10.1080/14017431.2016.1215519DOI
- https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-313436URI
- https://lup.lub.lu.se/record/209cae9e-8063-41e0-bd6c-058c487b31aaURI
- http://kipublications.ki.se/Default.aspx?queryparsed=id:134844939URI
Supplementary language notes
- Language:English
- Summary in:English
Part of subdatabase
- SwePubSwePub
Classification
Notes
- Objective Our aim was to study the risk of a first ischemic stroke in patients with atrial fibrillation (AF) treated in primary health care. Design The study population included all adults (n = 11,517), 45 years and older diagnosed with AF, from 75 primary care centres in Sweden between 2001 and 2007. Ischemic stroke was defined as a hospital care event of stroke between 2001 and 2010. Association between incident stroke and warfarin treatment was explored using Cox regression analysis, with hazard ratios (HRs), and 95% confidence intervals (95% CIs). Adjustment was made for age, socioeconomic factors and co-morbidity. Results Persistent treatment with warfarin was present among 34.7% of women and 40.9% among men. Persistent warfarin treatment, compared to no persistent treatment, was associated with a stroke preventing effect with fully adjusted HRs of 0.25 (95% CI 0. 0.26-0.45) in women, and 0.25 (95% CI 0.28-0.43) in men. A CHA2DS2-VASc score of at least two among women, and three among men, was associated with a stroke risk exceeding 18% during a mean follow-up of 5.4 years. Risk of haemorrhagic stroke was not increased. Conclusions Warfarin is effective in preventing stroke in AF patients in primary health care.
Subject headings and genre
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine hsv//eng
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Neurologi hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine Neurology hsv//eng
- Atrial fibrillation
- ischaemic stroke
- gender
- follow-up
- co-morbidity
- anticoagulant
- Hälsa och välfärd
- Health and Welfare
- anticoagulant
- Atrial fibrillation
- co-morbidity
- follow-up
- gender
- ischaemic stroke
Added entries (persons, corporate bodies, meetings, titles ...)
- Carlsson, Axel C.Karolinska Institutet,Uppsala universitet,Kardiovaskulär epidemiologi,Karolinska Inst, Div Family Med, Dept Neurobiol Care Sci & Soc, Huddinge, Sweden(Swepub:uu)axeca883 (author)
- Holzmann, Martin JKarolinska Institutet (author)
- Ärnlöv, Johan,1970-Högskolan Dalarna,Medicinsk vetenskap,Uppsala universitet,Kardiovaskulär epidemiologi,Dalarna Univ, Sch Hlth & Social Studies, Falun, Sweden.(Swepub:uu)johaarnl (author)
- Johansson, Sven ErikLund University,Lunds universitet,Allmänmedicin och klinisk epidemiologi,Forskargrupper vid Lunds universitet,Family Medicine and Clinical Epidemiology,Lund University Research Groups(Swepub:lu)med-skj (author)
- Sundquist, JanLund University,Lunds universitet,Allmänmedicin och klinisk epidemiologi,Forskargrupper vid Lunds universitet,Family Medicine and Clinical Epidemiology,Lund University Research Groups(Swepub:lu)med-jsu (author)
- Sundquist, KristinaLund University,Lunds universitet,Allmänmedicin, kardiovaskulär epidemiologi och levnadsvanor,Forskargrupper vid Lunds universitet,Family Medicine, Cardiovascular Epidemiology and Lifestyle,Lund University Research Groups(Swepub:lu)med-ksq (author)
- Karolinska InstitutetKardiovaskulär epidemiologi (creator_code:org_t)
Related titles
- In:Scandinavian Cardiovascular Journal: Informa UK Limited50:5-6, s. 311-3161401-74311651-2006
Internet link
- https://europepmc.org/articles/pmc5152680?pdf=render
- http://dx.doi.org/10.1080/14017431.2016.1215519FULLTEXT
- https://urn.kb.se/resolve?urn=urn:nbn:se:du-22659
- https://doi.org/10.1080/14017431.2016.1215519
- https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-313436
- https://lup.lub.lu.se/record/209cae9e-8063-41e0-bd6c-058c487b31aa
- http://kipublications.ki.se/Default.aspx?queryparsed=id:134844939
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