Search: id:"swepub:oai:DiVA.org:du-22659" >
Warfarin treatment ...
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Wändell, PerKarolinska Institutet
(author)
Warfarin treatment and risk of stroke among primary care patients with atrial fibrillation
- Article/chapterEnglish2016
Publisher, publication year, extent ...
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2016-08-18
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Informa UK Limited,2016
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printrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:du-22659
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https://urn.kb.se/resolve?urn=urn:nbn:se:du-22659URI
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https://doi.org/10.1080/14017431.2016.1215519DOI
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-313436URI
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https://lup.lub.lu.se/record/209cae9e-8063-41e0-bd6c-058c487b31aaURI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:134844939URI
Supplementary language notes
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Language:English
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Summary in:English
Part of subdatabase
Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Objective Our aim was to study the risk of a first ischemic stroke in patients with atrial fibrillation (AF) treated in primary health care. Design The study population included all adults (n = 11,517), 45 years and older diagnosed with AF, from 75 primary care centres in Sweden between 2001 and 2007. Ischemic stroke was defined as a hospital care event of stroke between 2001 and 2010. Association between incident stroke and warfarin treatment was explored using Cox regression analysis, with hazard ratios (HRs), and 95% confidence intervals (95% CIs). Adjustment was made for age, socioeconomic factors and co-morbidity. Results Persistent treatment with warfarin was present among 34.7% of women and 40.9% among men. Persistent warfarin treatment, compared to no persistent treatment, was associated with a stroke preventing effect with fully adjusted HRs of 0.25 (95% CI 0. 0.26-0.45) in women, and 0.25 (95% CI 0.28-0.43) in men. A CHA2DS2-VASc score of at least two among women, and three among men, was associated with a stroke risk exceeding 18% during a mean follow-up of 5.4 years. Risk of haemorrhagic stroke was not increased. Conclusions Warfarin is effective in preventing stroke in AF patients in primary health care.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
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Carlsson, Axel C.Karolinska Institutet,Uppsala universitet,Kardiovaskulär epidemiologi,Karolinska Inst, Div Family Med, Dept Neurobiol Care Sci & Soc, Huddinge, Sweden(Swepub:uu)axeca883
(author)
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Holzmann, Martin JKarolinska Institutet
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Ärnlöv, Johan,1970-Högskolan Dalarna,Medicinsk vetenskap,Uppsala universitet,Kardiovaskulär epidemiologi,Dalarna Univ, Sch Hlth & Social Studies, Falun, Sweden.(Swepub:uu)johaarnl
(author)
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Johansson, Sven ErikLund University,Lunds universitet,Allmänmedicin och klinisk epidemiologi,Forskargrupper vid Lunds universitet,Family Medicine and Clinical Epidemiology,Lund University Research Groups(Swepub:lu)med-skj
(author)
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Sundquist, JanLund University,Lunds universitet,Allmänmedicin och klinisk epidemiologi,Forskargrupper vid Lunds universitet,Family Medicine and Clinical Epidemiology,Lund University Research Groups(Swepub:lu)med-jsu
(author)
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Sundquist, KristinaLund University,Lunds universitet,Allmänmedicin, kardiovaskulär epidemiologi och levnadsvanor,Forskargrupper vid Lunds universitet,Family Medicine, Cardiovascular Epidemiology and Lifestyle,Lund University Research Groups(Swepub:lu)med-ksq
(author)
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Karolinska InstitutetKardiovaskulär epidemiologi
(creator_code:org_t)
Related titles
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In:Scandinavian Cardiovascular Journal: Informa UK Limited50:5-6, s. 311-3161401-74311651-2006
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