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Importance of hospi...
Importance of hospital and clinical factors for early mortality in Takotsubo syndrome: Insights from the Swedish Coronary Angiography and Angioplasty Registry.
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- Gudmundsson, Thorsteinn (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Univ Gothenburg, Sweden
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- Redfors, Björn (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Univ Gothenburg, Sweden
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- Råmunddal, Truls, 1973 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Univ Gothenburg, Sweden
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- Angerås, Oskar, 1976 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Univ Gothenburg, Sweden
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- Petursson, Petur, 1973 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Univ Gothenburg, Sweden
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- Rawshani, Araz, 1986 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Univ Gothenburg, Sweden
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- Hagström, Henrik (author)
- Umea Univ Hosp, Sweden
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- Alfredsson, Joakim (author)
- Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Kardiologiska kliniken US
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- Ekenbäck, Christina (author)
- Danderyd Hosp, Sweden
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- Henareh, Loghman (author)
- Karolinska Univ Hosp, Sweden
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- Skoglund, Kristofer, 1976 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Univ Gothenburg, Sweden
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- Ljungman, Charlotta, 1977 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Univ Gothenburg, Sweden
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- Mohammad, Moman (author)
- Skane Univ Hosp, Sweden
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- Jernberg, Tomas (author)
- Karolinska Institutet
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- Fröbert, Ole (author)
- Orebro Univ Hosp, Sweden
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- Erlinge, David (author)
- Skane Univ Hosp, Sweden
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- Omerovic, Elmir, 1968 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Univ Gothenburg, Sweden
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(creator_code:org_t)
- BMC, 2024
- 2024
- English.
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In: BMC Cardiovascular Disorders. - : BMC. - 1471-2261. ; 24:1
- Related links:
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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http://kipublication...
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Abstract
Subject headings
Close
- Takotsubo syndrome (TTS) is an acute heart failure syndrome with symptoms similar to acute myocardial infarction. TTS is often triggered by acute emotional or physical stress and is a significant cause of morbidity and mortality. Predictors of mortality in patients with TS are not well understood, and there is a need to identify high-risk patients and tailor treatment accordingly. This study aimed to assess the importance of various clinical factors in predicting 30-day mortality in TTS patients using a machine learning algorithm.We analyzed data from the nationwide Swedish Coronary Angiography and Angioplasty Registry (SCAAR) for all patients with TTS in Sweden between 2015 and 2022. Gradient boosting was used to assess the relative importance of variables in predicting 30-day mortality in TTS patients.Of 3,180 patients hospitalized with TTS, 76.0% were women. The median age was 71.0 years (interquartile range 62-77). The crude all-cause mortality rate was 3.2% at 30 days. Machine learning algorithms by gradient boosting identified treating hospitals as the most important predictor of 30-day mortality. This factor was followed in significance by the clinical indication for angiography, creatinine level, Killip class, and age. Other less important factors included weight, height, and certain medical conditions such as hyperlipidemia and smoking status.Using machine learning with gradient boosting, we analyzed all Swedish patients diagnosed with TTS over seven years and found that the treating hospital was the most significant predictor of 30-day mortality.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Keyword
- Humans
- Female
- Sweden
- epidemiology
- Male
- Registries
- Aged
- Takotsubo Cardiomyopathy
- mortality
- diagnostic imaging
- therapy
- diagnosis
- physiopathology
- Risk Factors
- Middle Aged
- Coronary Angiography
- Time Factors
- Risk Assessment
- Machine Learning
- Prognosis
- Predictive Value of Tests
- Aged
- 80 and over
- Hospitals
- Takotsubo syndrome; 30-day mortality; Machine learning; Predictors of mortality; Swedish Coronary Angiography and Angioplasty Registry (SCAAR); Gradient boosting
Publication and Content Type
- ref (subject category)
- art (subject category)
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Gudmundsson, Tho ...
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Redfors, Björn
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Råmunddal, Truls ...
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Angerås, Oskar, ...
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Petursson, Petur ...
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Rawshani, Araz, ...
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Hagström, Henrik
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Alfredsson, Joak ...
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Ekenbäck, Christ ...
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Henareh, Loghman
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Skoglund, Kristo ...
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Ljungman, Charlo ...
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Mohammad, Moman
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Jernberg, Tomas
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Fröbert, Ole
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Erlinge, David
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Omerovic, Elmir, ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Cardiac and Card ...
- Articles in the publication
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BMC Cardiovascul ...
- By the university
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University of Gothenburg
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Linköping University
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Karolinska Institutet