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Effects of reduced ...
Effects of reduced sedentary time on cardiometabolic health in adults with metabolic syndrome : A three-month randomized controlled trial
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- Garthwaite, Taru (author)
- University Of Turku, Turku, Finland
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- Sjöros, Tanja (author)
- University Of Turku, Turku, Finland
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- Laine, Saara (author)
- University Of Turku, Turku, Finland
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- Vähä-Ypyä, Henri (author)
- Ukk Institute For Health Promotion Research, Tampere, Finland
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- Löyttyniemi, Eliisa (author)
- University Of Turku, Turku, Finland
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- Sievänen, Harri (author)
- Ukk Institute For Health Promotion Research, Tampere, Finland
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- Houttu, Noora (author)
- University Of Turku, Turku, Finland
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- Laitinen, Kirsi (author)
- University Of Turku, Turku, Finland
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- Kalliokoski, Kari (author)
- University Of Turku, Turku, Finland
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- Vasankari, Tommi (author)
- Ukk Institute For Health Promotion Research, Tampere, Finland; University Of Tampere, Tampere, Finland
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- Knuuti, Juhani (author)
- University Of Turku, Turku, Finland
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- Heinonen, Ilkka, 1982- (author)
- Högskolan i Halmstad,Akademin för företagande, innovation och hållbarhet,University Of Turku, Turku, Finland
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(creator_code:org_t)
- Chatswood : Elsevier Ltd, 2022
- 2022
- English.
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In: Journal of Science and Medicine in Sport. - Chatswood : Elsevier Ltd. - 1440-2440 .- 1878-1861. ; 25:7, s. 579-585
- Related links:
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
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- Objectives: To investigate if reducing sedentary behavior improves cardiometabolic biomarkers in adults with metabolic syndrome. Design: Randomized controlled trial. Methods: Sixty-four sedentary middle-aged adults with metabolic syndrome were randomized into intervention (INT; n = 33) and control (CON; n = 31) groups. INT was guided to limit sedentary behavior by 1 h/day through increased standing and light-intensity physical activity. CON was instructed to maintain usual habits. Sedentary behavior, breaks in sedentary behavior, standing, and physical activity were measured with hip-worn accelerometers for three months. Fasting blood sampling and measurements of anthropometrics, body composition, and blood pressure were performed at baseline and at three months. Linear mixed models were used for statistical analyses. Results: INT reduced sedentary behavior by 50 (95% CI: 24, 73) min/day by increasing light-intensity and moderate-to-vigorous physical activity (19 [8, 30] and 24 [14, 34] min/day, respectively). Standing increased also, but non-significantly (6 [−11, 23] min/day). CON maintained baseline activity levels. Significant intervention effects favoring INT occurred in fasting insulin (INT: 83.4 [68.7, 101.2] vs. CON: 102.0 [83.3, 125.0] pmol/l at three months), insulin resistance (HOMA-IR; 3.2 [2.6, 3.9] vs. 4.0 [3.2, 4.9]), HbA1c (37 [36, 38] vs. 38 [37, 39] mmol/mol), and liver enzyme alanine aminotransferase (28 [24, 33] vs. 33 [28, 38] U/l). Conclusions: Reducing sedentary behavior by 50 min/day and increasing light-intensity and moderate-to-vigorous activity showed benefits in several cardiometabolic biomarkers in adults with metabolic syndrome. Replacing some of the daily sedentary behavior with light-intensity and moderate-to-vigorous physical activity may help in cardiometabolic disease prevention in risk populations. © 2022 The Authors
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Näringslära (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Nutrition and Dietetics (hsv//eng)
Keyword
- Cardiovascular risk factors
- Metabolic syndrome
- Physical activity
- Sedentary behavior
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Garthwaite, Taru
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Sjöros, Tanja
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Laine, Saara
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Vähä-Ypyä, Henri
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Löyttyniemi, Eli ...
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Sievänen, Harri
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Houttu, Noora
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Laitinen, Kirsi
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Kalliokoski, Kar ...
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Vasankari, Tommi
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Knuuti, Juhani
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Heinonen, Ilkka, ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Health Sciences
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and Nutrition and Di ...
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Journal of Scien ...
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Halmstad University