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Neoehrlichia mikure...
Neoehrlichia mikurensis & nbsp;Causing Thrombosis and Relapsing Fever in a Lymphoma Patient Receiving Rituximab
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- Sjöwall, Johanna (författare)
- Linköpings universitet,Avdelningen för inflammation och infektion,Medicinska fakulteten,Region Östergötland, Infektionskliniken i Östergötland
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- Kling, Kristian (författare)
- Region Östergötland, Medicinkliniken ViN
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- Ochoa-Figueroa, Miguel (författare)
- Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Centrum för medicinsk bildvetenskap och visualisering, CMIV,Region Östergötland, Fysiologiska kliniken US
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- Zachrisson, Helene (författare)
- Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Fysiologiska kliniken US
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- Wennerås, Christine, 1963 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för infektionssjukdomar,Institute of Biomedicine, Department of Infectious Medicine,Sahlgrens Univ Hosp, Sweden; Univ Gothenburg, Sweden
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(creator_code:org_t)
- 2021-10-12
- 2021
- Engelska.
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Ingår i: Microorganisms. - : MDPI AG. - 2076-2607. ; 9:10
- Relaterad länk:
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https://www.mdpi.com...
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https://liu.diva-por... (primary) (Raw object)
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https://gup.ub.gu.se...
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https://doi.org/10.3...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- Neoehrlichia (N.) mikurensis, an intracellular tick-borne bacterium not detected by routine blood culture, is prevalent in ticks in Scandinavia, Central Europe and Northern Asia, and may cause long-standing fever, nightly sweats, migrating pain, skin rashes and thromboembolism, especially in patients treated with rituximab. The multiple symptoms may raise suspicion of both infection, inflammation and malignancy, and lead in most cases to extensive medical investigations across many medical specialist areas and a delay of diagnosis. We describe a complex, albeit typical, case of neoehrlichiosis in a middle-aged splenectomised male patient with a malignant lymphoma, receiving treatment with rituximab. The multifaceted clinical picture associated with this tick-borne disease is addressed, and longitudinal clinical and laboratory data, as well as imaging, are provided. Longstanding relapsing fever in combination with thrombosis in superficial and deep veins in an immunocompromised patient living in a tick-endemic region should raise the suspicion of the emerging tick-borne disease neoehrlichiosis. Given the varied clinical presentation and the risk of delay in diagnosis and treatment, we believe it is important to raise clinicians' awareness of this emerging infection, which is successfully treated with doxycycline.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Infektionsmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Infectious Medicine (hsv//eng)
- NATURVETENSKAP -- Biologi -- Mikrobiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Microbiology (hsv//eng)
Nyckelord
- Neoehrlichia mikurensis
- tick-borne disease
- fever
- thrombosis
- rituximab
- splenectomy
- malignant lymphoma
- mikurensis
- infections
- Microbiology
- Neoehrlichia mikurensis; tick-borne disease; fever; thrombosis; rituximab; splenectomy; malignant lymphoma
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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