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  • Chang, KekeDepartment of Electrical Engineering, Henan Agricultural University, Zhengzhou, China (författare)

Considerations on Circuit Design and Data Acquisition of a Portable Surface Plasmon Resonance Biosensing System

  • Artikel/kapitelEngelska2015

Förlag, utgivningsår, omfång ...

  • 2015-08-19
  • MDPI AG,2015
  • printrdacarrier

Nummerbeteckningar

  • LIBRIS-ID:oai:DiVA.org:hig-20199
  • https://urn.kb.se/resolve?urn=urn:nbn:se:hig:diva-20199URI
  • https://doi.org/10.3390/s150820511DOI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

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Klassifikation

  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • Funding Agency:Grant Number National Natural Science Foundation of China  Grant no: U1304305 State Key Laboratory of Wheat and Maize Crop Science Grant no: SKL2014ZH-06 Henan Province Science and Technology Cooperation Program Grant no: 132106000073 
  • The aim of this study was to develop a circuit for an inexpensive portable biosensing system based on surface plasmon resonance spectroscopy. This portable biosensing system designed for field use is characterized by a special structure which consists of a microfluidic cell incorporating a right angle prism functionalized with a biomolecular identification membrane, a laser line generator and a data acquisition circuit board. The data structure, data memory capacity and a line charge-coupled device (CCD) array with a driving circuit for collecting the photoelectric signals are intensively focused on and the high performance analog-to-digital (A/D) converter is comprehensively evaluated. The interface circuit and the photoelectric signal amplifier circuit are first studied to obtain the weak signals from the line CCD array in this experiment. Quantitative measurements for validating the sensitivity of the biosensing system were implemented using ethanol solutions of various concentrations indicated by volume fractions of 5%, 8%, 15%, 20%, 25%, and 30%, respectively, without a biomembrane immobilized on the surface of the SPR sensor. The experiments demonstrated that it is possible to detect a change in the refractive index of an ethanol solution with a sensitivity of 4.99838 × 10(5) ΔRU/RI in terms of the changes in delta response unit with refractive index using this SPR biosensing system, whereby the theoretical limit of detection of 3.3537 × 10(-5) refractive index unit (RIU) and a high linearity at the correlation coefficient of 0.98065. The results obtained from a series of tests confirmed the practicality of this cost-effective portable SPR biosensing system.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Chen, RuipengDepartment of Electrical Engineering, Henan Agricultural University, Zhengzhou, China (författare)
  • Wang, ShunDepartment of Electrical Engineering, Henan Agricultural University, Zhengzhou, China (författare)
  • Li, JianweiDepartment of Electrical Engineering, Henan Agricultural University, Zhengzhou, China (författare)
  • Hu, XinranSchool of Human Nutrition and Dietetics, McGill University, Canada. (författare)
  • Liang, Hao (författare)
  • Cao, BaiqiongDepartment of Electrical Engineering, Henan Agricultural University, Zhengzhou, China (författare)
  • Sun, XiaohuiDepartment of Electrical Engineering, Henan Agricultural University, Zhengzhou, China (författare)
  • Ma, LiuzhengDepartment of Electrical Engineering, Henan Agricultural University, Zhengzhou, China (författare)
  • Zhu, JuanhuaDepartment of Electrical Engineering, Henan Agricultural University, Zhengzhou, China (författare)
  • Jiang, MinCollege of life sciences, Henan Agricultural University, Zhengzhou, China (författare)
  • Hu, JiandongDepartment of Electrical Engineering, Henan Agricultural University, Zhengzhou, China; State key laboratory of wheat and maize crop science, Zhengzhou, China (författare)
  • Department of Electrical Engineering, Henan Agricultural University, Zhengzhou, ChinaSchool of Human Nutrition and Dietetics, McGill University, Canada. (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Sensors: MDPI AG15:8, s. 20511-205231424-8220

Internetlänk

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  • Sensors (Sök värdpublikationen i LIBRIS)

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