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  • Wallin, EwaUppsala universitet,Anestesiologi och intensivvård,Department of Surgical Sciences - Anaestesiology & Intensive Care, Uppsala University, Uppsala Sweden (författare)

Characteristics of jugular bulb oxygen saturation in patients after cardiac arrest: A prospective study

  • Artikel/kapitelEngelska2018

Förlag, utgivningsår, omfång ...

  • 2018-05-24
  • Wiley,2018
  • printrdacarrier

Nummerbeteckningar

  • LIBRIS-ID:oai:DiVA.org:hig-26622
  • https://urn.kb.se/resolve?urn=urn:nbn:se:hig:diva-26622URI
  • https://doi.org/10.1111/aas.13162DOI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-364137URI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • Funding: Department of Surgical Sciences-Anaesthesiology & Intensive Care, Uppsala University, Sweden
  • BACKGROUND:Using cerebral oxygen venous saturation post-cardiac arrest (CA) is limited because of a small sample size and prior to establishment of target temperature management (TTM). We aimed to describe variations in jugular bulb oxygen saturation during intensive care in relation to neurological outcome at 6 months post- CA in cases where TTM 33°C was applied.METHOD:Prospective observational study in patients over 18 years, comatose immediately after resuscitation from CA. Patients were treated with TTM 33°C M and received a jugular bulb catheter within the first 26 hours post-CA. Neurological outcome was assessed at 6 months using the Cerebral Performance Categories (CPC) and dichotomized into good (CPC 1-2) and poor outcome (CPC 3-5).RESULTS:Seventy-five patients were included and 37 (49%) patients survived with a good outcome at 6 months post-CA. No differences were found between patients with good outcome and poor outcome in jugular bulb oxygen saturation. Higher values were seen in differences in oxygen content between central venous oxygen saturation and jugular bulb oxygen saturation in patients with good outcome compared to patients with poor outcome at 6 hours (12 [8-21] vs 5 [-0.3 to 11]% P = .001) post-CA. Oxygen extraction fraction from the brain illustrated lower values in patients with poor outcome compared to patients with good outcome at 96 hours (14 [9-23] vs 31 [25-34]% P = .008).CONCLUSIONS:Oxygen delivery and extraction differed in patients with a good outcome compared to those with a poor outcome at single time points. Based on the present findings, the usefulness of jugular bulb oxygen saturation for prognostic purposes is uncertain in patients treated with TTM 33°C post-CA.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Larsson, Ing-Marie,1963-Uppsala universitet,Anestesiologi och intensivvård,Department of Surgical Sciences - Anaestesiology & Intensive Care, Uppsala University, Uppsala Sweden(Swepub:uu)ingla697 (författare)
  • Nordmark-Grass, JohannaUppsala universitet,Anestesiologi och intensivvård,Department of Surgical Sciences - Anaestesiology & Intensive Care, Uppsala University, Uppsala Sweden(Swepub:uu)jonor764 (författare)
  • Rosenqvist, IvanUppsala universitet,Anestesiologi och intensivvård,Department of Surgical Sciences - Anaestesiology & Intensive Care, Uppsala University, Uppsala Sweden (författare)
  • Kristofferzon, Marja-Leena,1950-Uppsala universitet,Högskolan i Gävle,Medicin- och vårdvetenskap,Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden,Vårdvetenskap,Faculty of Health and Occupational Studies, Department of Health and Caring Sciences, University of Gävle, Gävle, Sweden(Swepub:uu)markr777 (författare)
  • Rubertsson, StenUppsala universitet,Anestesiologi och intensivvård,Department of Surgical Sciences - Anaestesiology & Intensive Care, Uppsala University, Uppsala Sweden(Swepub:uu)stenrube (författare)
  • Uppsala universitetAnestesiologi och intensivvård (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Acta Anaesthesiologica Scandinavica: Wiley62:9, s. 1237-12450001-51721399-6576

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