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IGEMS : The Consortium on Interplay of Genes and Environment Across Multiple Studies - An Update

Pedersen, Nancy L. (författare)
Karolinska Institutet
Gatz, Margaret (författare)
Center for Economic and Social Research, University of Southern California, Los Angeles, CA, United States
Finch, Brian K. (författare)
Center for Economic and Social Research, University of Southern California, Los Angeles, CA, United States
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Finkel, Deborah (författare)
Department of Psychology, Indiana University Southeast, New Albany, IN, United States
Butler, David A. (författare)
Office of Military and Veterans Health, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine, Washington, DC, United States
Dahl Aslan, Anna, 1975- (författare)
Karolinska Institutet,Jönköping University,HHJ, Institutet för gerontologi,HHJ. ARN-J (Aging Research Network - Jönköping),Institute of Gerontology and Aging Research Network – Jönköping (ARN-J) ; School of Health and Welfare, Jönköping University, Sweden
Franz, Carol E. (författare)
Department of Psychiatry, University of California San Diego, San diego, CA, United States
Kaprio, Jaakko (författare)
Department of Public Health,Faculty of Medicine, Institute for Molecular Medicine FIMM, HiLIFE, University of Helsinki, Helsinki, Finland
Lapham, Susan (författare)
Research and Evaluation, American Institutes for Research, Washington, DC, United States
McGue, Matt (författare)
Karolinska Institutet
Mosing, Miriam A. (författare)
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden ; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden
Neiderhiser, Jenae (författare)
Department of Psychology, Penn State University, University Park, PA, United States
Nygaard, Marianne (författare)
Danish Twin Registry, University of Southern Denmark, Odense C, Denmark
Panizzon, Matthew (författare)
Department of Psychiatry, University of California San Diego, San diego, CA, United States
Prescott, Carol A. (författare)
Department of Psychology, University of Southern California, Los Angeles, CA, United States
Reynolds, Chandra A. (författare)
Department of Psychology, University of California-Riverside, Riverside, CA, United States
Sachdev, Perminder (författare)
Centre for Healthy Brain Ageing (CHeBA), University of New South Wales, Sydney, NSW, Australia
Whitfield, Keith E. (författare)
Department of Psychology, Wayne State University, Detroit, MI, United States
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 (creator_code:org_t)
2019-09-23
2019
Engelska.
Ingår i: Twin Research and Human Genetics. - : Cambridge University Press. - 1832-4274 .- 1839-2628. ; 22:6, s. 809-816
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • The Interplay of Genes and Environment across Multiple Studies (IGEMS) is a consortium of 18 twin studies from 5 different countries (Sweden, Denmark, Finland, United States, and Australia) established to explore the nature of gene-environment (GE) interplay in functioning across the adult lifespan. Fifteen of the studies are longitudinal, with follow-up as long as 59 years after baseline. The combined data from over 76,000 participants aged 14-103 at intake (including over 10,000 monozygotic and over 17,000 dizygotic twin pairs) support two primary research emphases: (1) investigation of models of GE interplay of early life adversity, and social factors at micro and macro environmental levels and with diverse outcomes, including mortality, physical functioning and psychological functioning; and (2) improved understanding of risk and protective factors for dementia by incorporating unmeasured and measured genetic factors with a wide range of exposures measured in young adulthood, midlife and later life.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Medicinska och farmaceutiska grundvetenskaper -- Medicinsk genetik (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Basic Medicine -- Medical Genetics (hsv//eng)

Nyckelord

dementia
early life adversity
gene–environment interplay
health
socioeconomic status

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